Gene Information

Name : iglC1 (FTF1357c)
Accession : YP_667441.1
Strain : Francisella tularensis FSC 198
Genome accession: NC_008245
Putative virulence/resistance : Virulence
Product : intracellular growth locus, subunit C
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1398479 - 1399114 bp
Length : 636 bp
Strand : -
Note : Similar to AAP58964.1 (Q7X3J5) IglC (23 kDa protein) from Francisella novicida (211 aa). BLAST Score = 405, Expect = e-112 Identities = 209/211 (99), Positives = 210/211 (99) Identical to FTF1712. It is part of the duplicated region 1374371..1408281 which

DNA sequence :
ATGATTATGAGTGAGATGATAACAAGACAACAGGTAACAAGTGGCGAGACCATTCATGTGAGAACTGATCCTACTGCATG
TATAGGATCTCATCCTAATTGTAGATTATTTATTGATTCTTTAACTATAGCTGGGGAGAAACTTGATAAAAATATCGTTG
CTATAGATGGTGGAGAGGATGTCACGAAAGCTGATTCGGCTACAGCTGCTGCTAGTGTAATACGTTTATCTATAACGCCA
GGCTCTATAAATCCAACAATAAGTATTACTCTTGGTGTTCTAATTAAATCAAATGTTAGAACTAAAATTGAAGAGAAAGT
TTCGAGTATATTACAAGCAAGTGCTACAGATATGAAAATTAAGTTAGGTAATTCTAATAAAAAACAAGAGTATAAAACTG
ATGAAGCATGGGGTATTATGATAGATCTATCTAATTTAGAGTTATATCCAATAAGTGCTAAGGCTTTTAGTATTAGTATA
GAGCCAACAGAACTTATGGGTGTTTCAAAAGATGGAATGAGATATCATATTATATCTATAGATGGTCTTACAACATCTCA
AGGAAGTTTGCCAGTATGTTGCGCAGCTAGCACAGATAAAGGAGTTGCTAAAATAGGATATATTGCAGCTGCATAG

Protein sequence :
MIMSEMITRQQVTSGETIHVRTDPTACIGSHPNCRLFIDSLTIAGEKLDKNIVAIDGGEDVTKADSATAAASVIRLSITP
GSINPTISITLGVLIKSNVRTKIEEKVSSILQASATDMKIKLGNSNKKQEYKTDEAWGIMIDLSNLELYPISAKAFSISI
EPTELMGVSKDGMRYHIISIDGLTTSQGSLPVCCAASTDKGVAKIGYIAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iglC2 YP_170617.1 intracellular growth locus subunit C Not tested FPI Protein 2e-94 100
iglC1 YP_170309.1 intracellular growth locus subunit C Not tested FPI Protein 2e-94 100
iglC AAP58964.1 IglC Not tested FPI Protein 7e-94 99
iglC1 YP_001891776.1 intracellular growth locus C protein Virulence FPI Protein 1e-92 99
iglC2 YP_001892271.1 intracellular growth locus protein C Virulence FPI Protein 1e-92 99
iglC1 YP_001121164.1 intracellular growth locus iglC Virulence FPI Protein 1e-93 99
iglC2 YP_001121567.1 intracellular growth locus iglC Virulence FPI Protein 1e-93 99