Gene Information

Name : Meso_4346 (Meso_4346)
Accession : YP_665963.1
Strain :
Genome accession: NC_008242
Putative virulence/resistance : Virulence
Product : type IV secretion/conjugal transfer ATPase
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 246932 - 249313 bp
Length : 2382 bp
Strand : -
Note : TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE, TrbE, VirB component of type IV transporter system; KEGG: sme:SMa1315 VirB4 type IV secretion protein

DNA sequence :
TTGCCTAGTACCGCGACCGTCAGGAGCCGTGAGCTCGAACCCGAGACCTTCATCCCCTACGTCCGCCACATCGATGAACG
GGTGATCGCGCTTGACTCCCGTGCCCTGATGGTGGTCATCGCGCTCGAAGGCGTGTCGTTCGAGACGGCCGACACGCTGG
ACCTCAATGCGCTGCACCGGGACCTCAACACGCTCTACCGCAACATCGCGGATGAGCGGCTGGCGCTGTGGACGCATGTC
GTTCGGCGACGCGACAACGAGTATCCTGACGGCGAATTCGCGAACGCCTTCTCGCGCACGCTGAACGACAAGTACCGCAA
CCGCATGATCGGCGAGGACTTGTTCCGCAACGATCTGTATCTCAGCCTCGTATGGCACCCGGGCAAGGATGCAGCCGAGC
GGGTGGCAGCGTTCCTGTCGAGATTGCGCAAGGCGCGGCGACGCGGGGTGGAGCTTGATGTGGATGCCCTCAAGCGTCTC
GACGACACCATCGTCGACGTTACAGCCGGCCTGAAGCGTTTCGGCCCGCGCGTTCTCACCCTTCAAGAGCGCGACGGCCT
TGTCTTCTCGGAGCCGAGCGAAGTGCTGCACCAACTGGTGGGCGGCCGCCGTGAAGCCGTGCCGCTGACCGAGGGCCGCG
TTTCATCGGCAATTTATTCCGACCGCGTCATTGTCGGACGCGAGACGGTCGAGATCCGTCACGAAGGATCGAGCCGTTAT
GCAGGCATGTTCGGTTTCAAGGAATATCCGGCCCGCACGCGGCCCGGCATGTTCGATGGCTTGTTGACCGTCCCCTATGA
ACTGATCCTGACCCAGAGCTTCTCATTCCTGTCGAAGTCAGATGCGAAGACGGTGATGGGACGCAAGCAGAACCAGATGG
TCAGCGCCGGCGACAAGGCCGGGTCGCAGCTCGAGGAGCTCGATGATGCGCTGGACGATTTGGAATCCAACCGCTTCGTG
CTGGGTAACCATCACTTGACGCTTACGGTCTTCGCCGGAACGGTGAGGGAATTAACGGACAATCTGGCGAAGAGCCGAAC
CCATCTGACCAACGGCGGCGCGGTCGTTGCGCGCGAGGATCTCGGGCTGGAAGCGGCCTGGTGGGCGCAGCTTCCCGGCA
ACTTCCGCTATCGCGTCCGCTCCGGCGCGATCACCTCGAAGAATTTCGCGGCCTTTTCGCCGTTTCATTCCTATCCGGTC
GGTCAGCGCGACGGCAACGAATGGGGACCTGCCGTTGCCATGCTGAAGACGGCGTCGGGATCTCCGCTCTATTTCAATCT
TCACTATGGCGATCTCGGCAACACCTTCATCGGCGGACCTTCCGGCTCTGGCAAGACGGTGCTGCTCAACTTCATCCTGT
CGCAGGGCGAGAAGTTTGATGCCAATATTGTGTTTTTCGACAAGGACCGCGGCGCCGATCTTTTCGTGCGCGCCGCCGGC
GGCACATACCTGCCGCTAAAAAATGGCCGGCCGACCGGCTGTGCCCCGCTGAAGGGCATGGAACTGACGCCGGAGAACAA
AGTGTTTCTGGCGCAATGGGTGACCAAGCTTGTCGGCTCGAAAACGCGAGAACTCTCCGTCGCGGAAACCCGCGACATCG
CCAATGCCATCGATGGGCTCGCCGATCTGCCGGTAGAGCGGCGCACGATCGGCGCGCTGCGCACCTTTCTCAACAACACC
GATCCCGAAGGCATCGCATCTCGATTGCGCCGCTGGGAGAGGGGAGGGCCGCTCGGTTGGGTATTCGATAACGTCATTGA
GGACATTGGCCTTGGAGACTTCGGTGTTGGCGGCAAGTTCGTCGGCTATGACATGACCGACTTCCTCGACAATGAGGAAA
TCCGCACGCCGCTGATGGCCTATCTCTTCCACCGGGTCGAGCAGCTGATCGACGGCCGCCGCATCATCATCGTGATCGAT
GAGTTCTGGAAGGCGCTTGCCGACGAAGGCTTTCGCGATCTCGCCCAGAACAAGCTCAAGACCATCCGCAAACAGAATGG
GCTCATGCTGTTCGCCACGCAAAGCCCGCGCGATGCGATCAACTCTCCGATTGCGCACACCATCATCGAGCAGTGCCCCA
CCCAGGTCTTCATGCCCAACTCGCGTGGCAGTCGAGCCGACTACGTCGACGGCTTCAAGCTCACCGAACGGGAATATGAG
CTGATCGCACGGGAGCTCTCCAACGAGAGCCGCCGCTTCATCGTCAAGCAGGGTCATAACAGCGTCGTCGCCGAGCTCAA
TCTCGGCGGCTTCGACGACGAACTCGCCGTGCTCTCCGGTCGCACCGCCAACGTCGAACTTGCCGATACGATCCGGGCGG
AGACCGGCGACGATCCGGAAGCATGGCTTCCTCTCTTCCAGCAGCAAAGGAGTGCAGGCTGA

Protein sequence :
MPSTATVRSRELEPETFIPYVRHIDERVIALDSRALMVVIALEGVSFETADTLDLNALHRDLNTLYRNIADERLALWTHV
VRRRDNEYPDGEFANAFSRTLNDKYRNRMIGEDLFRNDLYLSLVWHPGKDAAERVAAFLSRLRKARRRGVELDVDALKRL
DDTIVDVTAGLKRFGPRVLTLQERDGLVFSEPSEVLHQLVGGRREAVPLTEGRVSSAIYSDRVIVGRETVEIRHEGSSRY
AGMFGFKEYPARTRPGMFDGLLTVPYELILTQSFSFLSKSDAKTVMGRKQNQMVSAGDKAGSQLEELDDALDDLESNRFV
LGNHHLTLTVFAGTVRELTDNLAKSRTHLTNGGAVVAREDLGLEAAWWAQLPGNFRYRVRSGAITSKNFAAFSPFHSYPV
GQRDGNEWGPAVAMLKTASGSPLYFNLHYGDLGNTFIGGPSGSGKTVLLNFILSQGEKFDANIVFFDKDRGADLFVRAAG
GTYLPLKNGRPTGCAPLKGMELTPENKVFLAQWVTKLVGSKTRELSVAETRDIANAIDGLADLPVERRTIGALRTFLNNT
DPEGIASRLRRWERGGPLGWVFDNVIEDIGLGDFGVGGKFVGYDMTDFLDNEEIRTPLMAYLFHRVEQLIDGRRIIIVID
EFWKALADEGFRDLAQNKLKTIRKQNGLMLFATQSPRDAINSPIAHTIIEQCPTQVFMPNSRGSRADYVDGFKLTEREYE
LIARELSNESRRFIVKQGHNSVVAELNLGGFDDELAVLSGRTANVELADTIRAETGDDPEAWLPLFQQQRSAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
virB4 YP_001610000.1 VirB4 protein Virulence Not named Protein 0.0 63
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 8e-138 41
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 1e-137 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Meso_4346 YP_665963.1 type IV secretion/conjugal transfer ATPase VFG2233 Protein 0.0 62
Meso_4346 YP_665963.1 type IV secretion/conjugal transfer ATPase VFG2259 Protein 2e-138 41