Gene Information

Name : Meso_4212 (Meso_4212)
Accession : YP_665836.1
Strain :
Genome accession: NC_008242
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 106341 - 109409 bp
Length : 3069 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC cadmium-translocating P-type ATPase heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase-like hydrolase E1-E2 ATPase-associated region; KEGG: mag:amb1012 cation transpor

DNA sequence :
ATGAAAGTTGATGCCGCGGCGACGGGCACTGCCGGCTCACTCCGGTTCAAGGTCGACGGCCTTGATTGCCAAAACGAGGT
CCGCGCGCTTCGCACAGCGGTAGGTCCCGTTGTGGGCGGTGACGACAAACTGTCCTTCCACACCCAAGCGGGCGTTATGG
AGGTGCTGTCCGGGAACCCTTCGGAGCTCGATGCCATTCAGCGGGCGGTTGCTACGACTGGAATGCGAGCGCATCTTCTG
CCGGAGGAGGCAGCGCGGCAAGCCGCACCGACACTCCTGTTCCGGGTCGAGGGGCTCGACTGCAAGAACGAAGTCGCGGC
GCTCAAGCGCGAAATCGGCCCGCTGGTCGGCGGCGACGCTTGGCTAATGTTTGACGCGACGAAAGGGCTCATGACCGTGG
CCCCGCAGCGAAAGGCGACGGTCGACGATATAATCGGCCACGTGGCCCGGACCGGAATGCGGGCTTCACTCGTCGTGGAG
GGTGCAGCCGAGGCAATGCTCTTTCGGGTCCAGGGCCTCGACTGCAAGAACGAGGTGGCGGCGCTCACGCGGGAACTCAC
ACCGCTCGTCGGCGAAAGCAAACTCGCTTTTGACACCGCCGAAGGCACGATGACGGTGGCCCCCCAGAGCCGAGCGGCGG
CAGACCTGATCGCCCAAGCCGTGGCTCGAACGGGCATGCGCGCCGAACTATGGGCGCCGCAGGCGGCCTCACCCGCTCCA
GCCCAGCCCGCCGTGGTACATGAGGGTTCGGCGTGCGGCTGCGGCGCAGAGGTGCAAGAGGTCTTCAGCCCGCCGATCCC
GACCCACTTACCCGGTCAGGTCGTGTTTCGCATTCATGGCATGGATTGTGCCGACGAGATCGCGGCCTTGAAGCGGGAGG
TTGGGCCGCTCGTCGGGGAAGACAAGCTCGCTTTTGATCTCCTCAACGGCCGCATGTCGATCGACGTGACACCGGATTCC
GTGCTCGAAGCCCGTATCGAAAAGGCGGTGGCTCGCGCCGGCCTACGCGCGGAGCCGTGGATCGAAGGTGGCATTAGCGA
AGCCGCACAGATCGAAGAGCGCCGCAAGCGGGTGCAGTCGTGGCTGACAACCGCAAGCGGCGTGCTCACCGCGCTGGGCT
TCGCGGTCCACGCTTGGCTCGGGGGCGGCGTCATAGCGGCTTTCGAGGCAGGCGAACATGCCATGGGCACAACCCCGTTG
CCGAGCATGGTTCTCTACGCGGTCGCCGTGCTCTGTGCCGCGCGCTACGTCGGGCCCAAGGCTTGGCTCGCGGCGAAGCG
ACTTCGACCCGACATGAATCTGCTGATGGTGGTTGCGGTCGCGGGCGCGATCGGCATCGGCGCCTGGTTCGAGGCCGCCA
CCGTTTCGTTCTTTTTTGCATTGGCGCTGGCGCTCGAGGCCTGGAGCCTTGGTCGCGCGCGCCGGGCAGTTGCCGCCCTT
ATGGAACTCGCGCCGCCGACGGCACGCGTCAAACTTGAAGACGGCTCCGAGCGCGACGTGCCGGCGGCCGAGGTGCGAGT
CGGCGCGCGGATCATAATCCGGCCGGGAGACAAGGTGCCGCTCGACGGCCGGGTTGCCGCTGGCGAGAGTGAGGTCAACC
AGGCACCGATCACCGGTGAAAGCGTGCCGGTATTCAAGGCAGAAGGCGACGACGTCTTTGCCGGGACCATCAACGGTGAG
GGTGCAATCGAGGTCGTGACCACCAAAGCGGCGAATGACACGACGCTTGCCCAGATTATCCGCATGGTCGGTTCGGCGCA
GAGCCGACGCGCGCCCAGTGAGCAATGGGTGGAGAAATTCGCGCGCGTCTACACACCCGTCGTGATGGTACTCGCCGTTG
CGATTTTTCTCGCTCCGCCCTTGCTCTTTGGCGGTGCCTGGGACGTCTGGTTCTACCGGGCTCTCGTGCTCCTCGTGATC
GCTTGCCCCTGCGCGCTCGTGATTTCGACCCCGGTGACGATCGTCGCGGCACTCGCCGGCGCGGCAAAGCAGGGTGTCTT
GGTAAAGGGCGGCACCCATCTCGAGACGCCTGCGCACCTCAAGGCGATTGCCTTGGACAAGACGGGCACGCTCACCGAAG
GACGACCGCAGGTCGTCGAGATTGTGCCGCTTCGAGGGCGCAGCGAAACTGAGCTCCTCGGCTTGGCCGCCGCCCTGGAG
GCGCGCAGCGGACATCCGATCGCTCGCGCCATCCTGGCGAAAGCCGCCGAACTGAAAATCGCCGCCGAGCCTGCCGAGGC
TGTCCAAGCTATCACTGGCCGAGGGGTCAGCGGGCGCGTGGCCGGTCGCGAGATGTGGCTCGGCTCGCGCCGCTACCTTG
AGGAGCGCGGTGTCAATTCTGCTGAGGTTCTGCAGCGGGCAGATGCGCTTTCGAGCGCCGGTCGCACTATCGTCGCGGTC
GGCGATGGTCGGGACGTCTGGGGACTCGTTGCCGTCGCCGATGCGGTCAGGCCGGAGGCCAAGGACATTGTCACGGCGCT
GCACCGCGCCGGGATCGGACACGTTGTGATGCTCACTGGAGACAATCGCGCGACAGCCGAGGCGATTGCGAAGCAGACGG
GCATCGACGAGGTCCAGGCAGAACTTCTACCTGGCGACAAGGTGGCGGCGGTCGAGGATTTGGTGCGGCGCTACGGATCG
GTGGCGATGGTCGGCGACGGAGTCAATGACGCTCCCGCGATGGGGCGCGCCAATCTCGGCATCGCCATGGGTGCCATGGG
CAGCGACGCCGCCATTGAAACGGCCGATGTTGCCCTCATGTCAGACGATCTTTCGAAACTTCCTTGGCTGGTGCGCCATT
CGCGCGCGACGCTCGCCGTCATCCGACAAAACGTTGCCTTCTCGATCGCTGTGAAGCTCTTGTTCACAGCGCTGACGGTG
ATTGGTCTCGCATCGCTCTGGGGTGCTATCGCGGCGGACGTCGGCGCGTCTCTGCTGGTCGTTCTCAATGGCCTGCGCCT
GCTCAATCGTGGTCAGACCAGCAGTCAAAAGGGTGGCCCATCCAGCGGCCTTGGCGTTTCGCTGCACCGGCATCGGGCCT
CGACGATCACCGAGACGGTCCCGGCGTAG

Protein sequence :
MKVDAAATGTAGSLRFKVDGLDCQNEVRALRTAVGPVVGGDDKLSFHTQAGVMEVLSGNPSELDAIQRAVATTGMRAHLL
PEEAARQAAPTLLFRVEGLDCKNEVAALKREIGPLVGGDAWLMFDATKGLMTVAPQRKATVDDIIGHVARTGMRASLVVE
GAAEAMLFRVQGLDCKNEVAALTRELTPLVGESKLAFDTAEGTMTVAPQSRAAADLIAQAVARTGMRAELWAPQAASPAP
AQPAVVHEGSACGCGAEVQEVFSPPIPTHLPGQVVFRIHGMDCADEIAALKREVGPLVGEDKLAFDLLNGRMSIDVTPDS
VLEARIEKAVARAGLRAEPWIEGGISEAAQIEERRKRVQSWLTTASGVLTALGFAVHAWLGGGVIAAFEAGEHAMGTTPL
PSMVLYAVAVLCAARYVGPKAWLAAKRLRPDMNLLMVVAVAGAIGIGAWFEAATVSFFFALALALEAWSLGRARRAVAAL
MELAPPTARVKLEDGSERDVPAAEVRVGARIIIRPGDKVPLDGRVAAGESEVNQAPITGESVPVFKAEGDDVFAGTINGE
GAIEVVTTKAANDTTLAQIIRMVGSAQSRRAPSEQWVEKFARVYTPVVMVLAVAIFLAPPLLFGGAWDVWFYRALVLLVI
ACPCALVISTPVTIVAALAGAAKQGVLVKGGTHLETPAHLKAIALDKTGTLTEGRPQVVEIVPLRGRSETELLGLAAALE
ARSGHPIARAILAKAAELKIAAEPAEAVQAITGRGVSGRVAGREMWLGSRRYLEERGVNSAEVLQRADALSSAGRTIVAV
GDGRDVWGLVAVADAVRPEAKDIVTALHRAGIGHVVMLTGDNRATAEAIAKQTGIDEVQAELLPGDKVAAVEDLVRRYGS
VAMVGDGVNDAPAMGRANLGIAMGAMGSDAAIETADVALMSDDLSKLPWLVRHSRATLAVIRQNVAFSIAVKLLFTALTV
IGLASLWGAIAADVGASLLVVLNGLRLLNRGQTSSQKGGPSSGLGVSLHRHRASTITETVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 9e-111 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-111 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Meso_4212 YP_665836.1 heavy metal translocating P-type ATPase BAC0298 Protein 8e-104 42