Gene Information

Name : fliI (Hac_0106)
Accession : YP_663960.1
Strain : Helicobacter acinonychis Sheeba
Genome accession: NC_008229
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 96012 - 97316 bp
Length : 1305 bp
Strand : -
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAACATTTTGATCTATCGCCTCGTTATGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGAATGGTTTTAACCCATCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCACTGAAT
GCGTGGGAATGGTGGTGGTGGTAGAAAAAGAACAATTTGGTTTCACGCCCTTTAATTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTACTGTTTTTAAAAGAGGGGTTGAATTTCCCTGTGGGGCATAATCTTTTAGGGCGGGTGCTTAACCCTTTAGG
GCAAGTAATTGACAATAAGGGGGCGTTGGATTATGAGCGATTGGCTCCAGTGATCACAACGCCTATAGCCCCCCTAAAAA
GGGGCTTGATTGATGAGATTTTTAGCGTGGGAGTGAAAAGCATTGATGGGCTTTTGACTTGCGGTAAGGGGCAAAAACTG
GGCATTTTTGCCGGCTCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGGTGCTTAGTGCCTATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACCTGCAAGGGGATTTAAGCTCTTGCG
TGTTGGTGGTCGCTACAAGCGATGATAGCCCTTTAATGCGAAAATACGGGGCGTTTTGCGCGATGAGCGTGGCAGAGTAT
TTTAAAAATCAAGGGCTAGATGTGTTGTTTATCATGGATTCAGTAACTCGTTTTGCTATGGCTCAAAGAGAAATTGGTTT
GGCTTTAGGCGAACCGCCCACCTCCAAAGGTTACCCTCCATCCGCGCTTTCCTTATTGCCTCAGTTAATGGAGAGAGCGG
GCAAAGAAGAGGGCAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTTGTAGAGGGCGATGATTTGAGTGATCCAATAGCC
GATCAAGCTAGGAGTATTTTAGATGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTATCCGCCTATCAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATTATCAGCGAGTCTCAAAACCTTTATGCAAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAGATGCTTATTCGCATCGGATCTTATCAAATGGGGAATGATAAAGAGCTTGATGAA
GCGATCAACAAAAAGGCTTTAATGGAGCAATTTTTAGTGCAAGATGAAAACGCCTTGCAGCCTTTTGAACAAAGTGCTAA
ACAATTAGAAGAAATCTTAAAATAA

Protein sequence :
MPLKSLKNRLNQHFDLSPRYGSVKKIMPNIVYANGFNPSVGDVVKIEKSDGTECVGMVVVVEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGHNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEIFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLVPIKVIALIGERGREIPEFIEKNLQGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEEGKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLYARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AINKKALMEQFLVQDENALQPFEQSAKQLEEILK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-73 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-77 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-77 46
escN AAC38383.1 EscN Virulence LEE Protein 1e-77 46
escN AAC31513.1 L0034 Virulence LEE Protein 8e-78 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-80 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-80 45
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-80 45
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-76 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-76 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-80 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-79 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-79 44
escN AAK26715.1 EscN Virulence LEE Protein 4e-76 44
escN AAL57542.1 EscN Virulence LEE Protein 4e-76 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-76 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-52 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-58 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-52 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-77 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-58 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-76 41
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-76 41
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-73 41
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-58 41
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 9e-59 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-53 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-53 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-53 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-53 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_663960.1 flagellum-specific ATP synthase VFG0390 Protein 3e-80 52
fliI YP_663960.1 flagellum-specific ATP synthase VFG0048 Protein 3e-79 51
fliI YP_663960.1 flagellum-specific ATP synthase VFG0192 Protein 5e-78 51
fliI YP_663960.1 flagellum-specific ATP synthase VFG2144 Protein 1e-77 47
fliI YP_663960.1 flagellum-specific ATP synthase VFG0812 Protein 5e-78 46
fliI YP_663960.1 flagellum-specific ATP synthase VFG0730 Protein 7e-78 46
fliI YP_663960.1 flagellum-specific ATP synthase VFG1254 Protein 7e-78 45
fliI YP_663960.1 flagellum-specific ATP synthase VFG2499 Protein 4e-73 43
fliI YP_663960.1 flagellum-specific ATP synthase VFG2331 Protein 2e-71 42
fliI YP_663960.1 flagellum-specific ATP synthase VFG1778 Protein 8e-56 42
fliI YP_663960.1 flagellum-specific ATP synthase VFG0555 Protein 5e-54 41