Gene Information

Name : lysS (Hac_0368)
Accession : YP_664204.1
Strain : Helicobacter acinonychis Sheeba
Genome accession: NC_008229
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 313191 - 314696 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTTCTAACCAATACATCCAACAACGCATTCATAAAGCCAACAGCTTGAGAGAAGAAGGGAAAAACCCTTATAAAAA
TGGCTTGAAACGAAGCCTAACAAACGCCGCTTTTTTAGAAAAATACGCTTATGTTAAGGATTTAGAAGGGCCTAAAGACA
AAGAAAAATGCGAGAGTATTGTAGGGAGGGTCAAGCTCTTGCGTTTAATGGGTAAGGCATGTTTTATTAAAATTGAAGAT
GAAAGTGCGATTTTACAAGCCTATGTTTCACAAAATGAATTGAACGATGAATTTAAAAGCCTAAAAAAGCATTTAGAAGT
GGGCGATATTGTGTTGGTGAAAGGCTTTCCTTTTGCCACTAAAACCGGTGAATTAAGCATTCATGCCCTAGAATTCCACA
TTTTAAGCAAAACCATTGTCCCCTTACCTGAAAAGTTTCATGGATTAAGCGATATAGAATTGCGTTACCGCCAGCGTTAC
TTGGATTTGATAGTCAATCCTAGCGTTAAAGATGTGTTTAAAAAGCGCAGTTTGATTGTCTCTAGCGTGCGTAAATTCTT
TGAAATGGAAGGCTTTTTGGAAGTAGAAACTCCGATGATGCACCCCATTCCTGGCGGGGCGAACGCAAGGCCTTTTATCA
CTTATCATAACGCTTTGGAAATTGAAAGGTATTTAAGGATTGCCCCAGAATTATACCTTAAACGCTTGATTGTAGGGGGT
TTTGAAGCGGTGTTTGAAATCAATCGTAATTTTAGGAATGAAGGCATGGATCATAGCCATAACCCCGAATTTACGATGAT
TGAGTTTTATTGGGCGTATCACACTTATGAAGATTTGATTGAACTAAGCAAGAGGTTATTTGACTACTTGCTAAAGACTT
TAAATTTAGATTCAAAAATCATTTATAACGACATGGAAGTGGATTTCAATCAAACGAGCGTGATTTCCTATTTAGACGCT
TTAGAAACAATAGGGGGCATTAGCAAGGAGATTCTAGAAAAAGAAGACAAACTTTTAGCTTATTTGTTAGAGCAAGGTAT
CAAAGTAGAGCCTAATCTCACTCATGGTAAATTACTCGCTGAAGCGTTTGATCGTTTTGTAGAACACCAACTTATTCACC
CCACTTTTGTAACCGAATACCCTATTGAGATTAGCCCGCTAGCCAGACGCAACGATAGTAACCCTAATATTGCTGACAGG
TTTGAATTGTTTATTGCAGGAAAAGAAATCGCTAACGGCTTTAGCGAATTGAATGACCCCTTAGATCAATTAGAACGCTT
TAAAAATCAAGTAGCCGAAAAAGAAAAAGGCGATGAAGAAGCCCAATACATGGACGAAGATTATGTGTGGGCGTTAGCTC
ATGGAATGCCCCCCACTGCAGGGCAAGGCATAGGCATTGACAGATTAGTGATGCTACTCACTGGGGCTAAAAGTATTAAA
GATGTGATTTTATTCCCAGCGATGCGTCCTGTTAAAAACGATTTTAATATTGAGAGTGAAGAATAA

Protein sequence :
MFSNQYIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKDLEGPKDKEKCESIVGRVKLLRLMGKACFIKIED
ESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRY
LDLIVNPSVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGG
FEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDA
LETIGGISKEILEKEDKLLAYLLEQGIKVEPNLTHGKLLAEAFDRFVEHQLIHPTFVTEYPIEISPLARRNDSNPNIADR
FELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGIDRLVMLLTGAKSIK
DVILFPAMRPVKNDFNIESEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 9e-106 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_664204.1 lysyl-tRNA synthetase VFG1668 Protein 5e-106 50