Gene Information

Name : serS (Hac_1740)
Accession : YP_665435.1
Strain : Helicobacter acinonychis Sheeba
Genome accession: NC_008229
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1516019 - 1517266 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAGAAAACTTTTATTACAAGATTTTGATAAGGTGGCTCATTCTTTAAAAAAGCGTAACAGCGTGATAGATGA
TGGGTTGGAGCGTTTGCGCGAAATCATCACGCATTATAAAAAACAACTCATTGAGTTAGAAAGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGTATCAAAATGACTCAAAAAGTGGATGCAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAGTTGAATGAGCTTTCCAAAAGCGTGAGCGAGTTGGAGCAAAAAATTGATTTAAAGCTTTCAATAATCCCTAA
TCTAGTGGATGAAAAAACCCCTTTAGGCACAAGCGAAGAAGATAATATAGAAATTAAAAAAATCTTAACCCCAAGAGATT
TCACTTTCACGCCTAAAGAGCATTTTGAACTCGCTCAAAAAAATGGCTGGATTGATTTTGAAAGCGGCGTGAAACTCGCT
AAAAGCCGTTTTTCAGTTATTAGGGGTTTTGGGGCCAAAGTTTATCGCGCGCTCATTCATTTAATGTTAGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCTTTAGTGAATGAAAAAATGCTTTTTGGGACTGGGCAATTACCCAAAT
TCAAAGAAGATGTTTTTAAAATAGAAAATGAAAATTTGTATTTGATCCCCACCGCTGAAGTAACGCTCACCAATTTATAC
AACGACACGATCATCAGCGTTGAAAAACTCCCGATTAAAATGACCGCACACACGCCTTGTTTCAGGAGCGAAGCAGGGAG
TGCGGGAAAAGACACAAGGGGGATGATAAGACAACACCAATTTGATAAGGTGGAATTAGTGGCTATCACACACCCTAAAG
AAAGCGATGTCATGCAAGAGTATATGCTAGAGAGCGCGAGTGGGATCTTAAAGGCTTTGGAATTACCTCATCGGTTTGTG
CAATTATGCAGTGGGGATTTGGGTTTTAGTGCAAGTAATACGATAGATATTGAAGTGTGGTTGCCTGGGCAAAATTGTTA
TAGAGAAATCAGCTCGGTGTCTAACACGAGAGATTTTCAAGCCAGGCGGGCTAAAATCCGCTTCAAGGAAAATCAAAAAA
ACCAATTAGTGCACACTCTAAATGGCTCTTCTTTAGCGGTAGGAAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCACATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDRKLLLQDFDKVAHSLKKRNSVIDDGLERLREIITHYKKQLIELESLQAFQNKVSKEFGIKMTQKVDASDLKKELENN
KIKLNELSKSVSELEQKIDLKLSIIPNLVDEKTPLGTSEEDNIEIKKILTPRDFTFTPKEHFELAQKNGWIDFESGVKLA
KSRFSVIRGFGAKVYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIISVEKLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDVMQEYMLESASGILKALELPHRFV
QLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLVHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-78 47