Gene Information

Name : hemC (Hac_1381)
Accession : YP_665114.1
Strain : Helicobacter acinonychis Sheeba
Genome accession: NC_008229
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1190670 - 1191590 bp
Length : 921 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
GTGGGAAAATTAGTGATTGGCTCTAGGGGGAGCGAATTGGCTTTATGGCAAGCGAATTATATTAAAGAACGCCTAAAAAA
AGAATGCTTTATAGAAAGCGAAATTCAAATCGTTAAAACCACAGGCGATAAGATTTTAGATGCACCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAAGAATTAGAAGAATTGCTTTTAAAAGGCACAATTGATTTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAAGGGTTAGATTTAGCATGCATTACCAAAAGAGCTGATGTGAGAGACACTTTTTTGAG
CACTAAATTCCCTGATTTGATGAGCTTGCCTAAAGGGGCAAAAGTAGGCACTACTTCTTTAAGGCGCTCCATGCAACTCA
AATGCAAACGAAAAGATCTAGACACAGAAAGTTTAAGGGGGAATGTCCAAACCCGTTTAAAAAAGCTTGAATCGGGCGAA
TTTGACGCTATCATTTTAGCTGAAGCCGGATTGTGCCGCCTAAACATTCAAGGGGCGAAATACCGCAAGGCTTTTAGCGT
GGAAGAAATGATTCCTAGCATGGGTCAAGGGGCTTTAGGGGTAGAAATGCTTAAAAGCCACAAGCATTTTACCGCACTTC
AAAAACTCAATGACGAAGAAAGCGCGTTTTGTTGCCATTTAGAAAGAGAGTTTATCAAAGGGCTTAATGGGGGGTGTCAA
ATCCCTGTGGGCGTGCATGCGAGTTTAATGGGTGAAAAAGTTAAAATCCAAGCCATTTTAGGCTTGCCTAATGGCGAAGA
AGTCATCGCTAAAGAAAAACAAGGGGATAAAAATAAGGCGTTTGATTCAGTTCAAGAGCTTTTAGAAGCCTTTTTGCAAA
GCGGAGCGAGAGAGATTTTAGAAAAGGTGCAATTGTTTTAA

Protein sequence : 
MGKLVIGSRGSELALWQANYIKERLKKECFIESEIQIVKTTGDKILDAPLNKIGGKGLFTKELEELLLKGTIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSTKFPDLMSLPKGAKVGTTSLRRSMQLKCKRKDLDTESLRGNVQTRLKKLESGE
FDAIILAEAGLCRLNIQGAKYRKAFSVEEMIPSMGQGALGVEMLKSHKHFTALQKLNDEESAFCCHLEREFIKGLNGGCQ
IPVGVHASLMGEKVKIQAILGLPNGEEVIAKEKQGDKNKAFDSVQELLEAFLQSGAREILEKVQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-43 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-43 46