Gene Information

Name : guaA (Patl_3119)
Accession : YP_662679.1
Strain : Pseudoalteromonas atlantica T6c
Genome accession: NC_008228
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3758182 - 3759759 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAACAAACATTCACGACCAACGCATACTCATTCTCGACTTCGGCTCTCAGTACACTCAACTTATCGCTCGTAGAGT
GCGCGAAATAGGCGTGTACTGTGAATTATGGGCATGGGATGTAACCGAAGAGCAAATTCGTGAATTTAATCCAAACGGTA
TTATTTTATCAGGTGGACCCGAATCTGTTCATGCAAAAGACTCGCCGCGTGCGCCGCAATATGTCTTTGATGCGGGGGTC
CCCGTATTTGGTATTTGCTACGGCATGCAAACCATGGCCGAACAGTTAGGCGGTGCCGTGTTAGGCTCAGATATGCGAGA
GTTTGGTTATGCTCAAGTGGAAGTGGTTGAGCAAATGGCATTACTCAATAACATCGAAGATCATGTTAGCCCTAATGGTA
ACGCATTGCTTGATGTATGGATGAGTCACGGTGATAAAGTGGCGGCGGTACCGGACGGGTTTATCACAGCAGCGAAAACC
GATAGTTGCCCATTTGCCGCGATCGTACACCCCGAAAAGCAATTCTACGGTGTGCAGTTTCACCCAGAAGTGACGCACAC
TCGTCAGGGGCAGCGCATGTTGTCGCATTTCGTGTTAGATATTTGTCAGTGCGAAAAACTCTGGACGCCTGACGCAATCA
TCGAGGATGCGGTTGCGCGCATGAAGAAGCAAATCGGTGATGACGAAGTTATCTTAGGGTTGTCGGGTGGTGTTGACTCA
TCAGTTGTGGCGATGTTGCTACACCGCGCGATTGGCAAAAACCTCACCTGTGTATTTGTGGATAACGGCTTGTTACGTTT
AAACGAAGGCCAACAAGTCATGGACATGTTCGGCGATCATTTTGGACTTAATATTATCAAAATTGATGCAGAAGAGCGCT
TCTTATCTGCATTGGCCGGTACGGATGAGCCTGAAGCAAAACGTAAGATAATAGGCCGTGTGTTTGTTGAAGTGTTCGAT
GAAGAATCGAAAAAGCTGAAAAATGCTAAGTGGTTGGCACAAGGTACGATTTATCCTGATGTAATCGAGTCAGCTGGCTC
TGCTACCGGTAAAGCTCACGTGATTAAATCACACCATAACGTTGGTGGTTTACCAGACGATATGGCGATGGGCTTGGTTG
AGCCATTGCGTGAATTGTTTAAAGACGAAGTACGCAAAATCGGCTTAGAGCTGGGTTTGCCTTATGACATGTTGTATCGC
CACCCATTCCCGGGGCCGGGGTTAGGTGTTCGGGTGTTAGGTGAAGTGAAAAAAGAATACTGTGACTTGTTGCGCCGCGC
TGATGCCATCTTTATCGATGAGCTACATAAGCATGATTTGTATAATAAGGTAAGCCAAGCCTTTACGGTTTTCCTACCTG
TGAAGTCAGTAGGCGTCATGGGCGATGCACGTAAATACGATTGGGTCGTATCATTGCGTGCAGTAGAGACGATTGATTTT
ATGACCGCGCATTGGGCCCATTTACCTTACGAATTTTTGGGTAAAGTTTCCAACCGCATTATCAACGAAATAGATGGTAT
CTCGCGAGTGGTATACGACATTTCAGGTAAGCCACCCGCCACTATTGAGTGGGAATAG

Protein sequence :
MTTNIHDQRILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPNGIILSGGPESVHAKDSPRAPQYVFDAGV
PVFGICYGMQTMAEQLGGAVLGSDMREFGYAQVEVVEQMALLNNIEDHVSPNGNALLDVWMSHGDKVAAVPDGFITAAKT
DSCPFAAIVHPEKQFYGVQFHPEVTHTRQGQRMLSHFVLDICQCEKLWTPDAIIEDAVARMKKQIGDDEVILGLSGGVDS
SVVAMLLHRAIGKNLTCVFVDNGLLRLNEGQQVMDMFGDHFGLNIIKIDAEERFLSALAGTDEPEAKRKIIGRVFVEVFD
EESKKLKNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMAMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIDELHKHDLYNKVSQAFTVFLPVKSVGVMGDARKYDWVVSLRAVETIDF
MTAHWAHLPYEFLGKVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-126 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-126 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-126 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-111 47