Gene Information

Name : serS (HQ3138A)
Accession : YP_658834.1
Strain : Haloquadratum walsbyi DSM 16790
Genome accession: NC_008212
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2461328 - 2462710 bp
Length : 1383 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATCGGCAACTGCTTCGTAAAAACCCTGATGCAATCCGGGGAGCCCTTGATGAAAAAGGGGTGACAGACGTCAA
TCTTGATCAGATTCTCACTCTTGATCAAGAATGGCGCGAACGTAAAGCTCGCGGGGATGAACTCCGACATGAGCGAAATC
AAATTTCGTCGAAGATTGGCAAACTAAAAGCTGCTGGTGATGAAGACGCCGCATCAGAAGCAATCGCGCAGTCACAAGAA
TTAAAAAATGAACTTGAGGAGATCGAGCGCGAAGCCGACAAATTAAAATCTGAACTCGATACGGCAATGCTCAAGATCCC
ACAAGTGCCAGATGATGCGGTTCCAGTTGGAACAGATGAATCGGAGAACGTTGAGCGGCGGCGTGAGGGGTTTGATTCGC
TCCGCTCGCTGCCTGATACTGTTATTCCGCATTATGACCTTGGCGAAGAATTAGAAATACTTGATTTCGAGCGAGGCGCC
AAAGTGACAGGCGGTGGGTTCTATTTCGCGAAAGGCGATGGTGCCCGACTTGAGCATGCTCTTGTGCAATTCATGCTTGA
TATTCACCGTGAACAAGGATATCAAGATGTTTTCCCGCCAATCCCGGTCAATTCACAATCAATGGTTGGAACCGGACAGT
TCCCAAAATTCACTGAGGATGCTTACCGTATTGGTGAGACAAATGATGAACCGTGGGATAATGATGATTTATGGCTCTGT
CCAACGGCTGAAGTCCCAGTCACGAACATGTATCGTGATGAGATTTTGTTAGACGATGATCTACCGGTGAAAATACAGGC
ATACACCCCAAACTTCCGTCGGGAAGCAGGAGAGCATGGAACCGAGACCCGTGGTATTGTTCGTGTTCATCAATTTAATA
AGGTCGAATTAGTGAATTTTGTTCGCCCGGAAGATAGCGCTGAGCGATTTGATGGACTGCTCACGGAAGCCGAGGTTGTG
CTCCAACGGCTTGGACTACCATATCGGATTCTTGAGATGTGTACAGGTGATTTAGGCTTCACACAGCGGAAAAAATACGA
TATTGAAGTCTGGGCACCAGGTGACGATATGGCGACCGGTCCAGACATTGGTGGTCGGTGGCTTGAGGTATCATCTGTGT
CAAACTTCGGTGCATTTCAATCACGGCGAGCAGGACTTCGATATCGACCTGAACGACATGAATCAGCCTCATATCTCCAT
ACACTGAATGGCTCAGGGGTTGCTGTTCCTCGTGTAATGGTTGCAATTATGGAGTATTATCAGAATGATGATGGCACAAT
TACCATTCCAGAACCACTTCAACCATACATGAACGGTCTAAGTGTAATTGAGGGACATGACCCAGTTGGCGAGGCAGCGG
TTGGTGCTGGAAAGCGTGAGTAA

Protein sequence :
MIDRQLLRKNPDAIRGALDEKGVTDVNLDQILTLDQEWRERKARGDELRHERNQISSKIGKLKAAGDEDAASEAIAQSQE
LKNELEEIEREADKLKSELDTAMLKIPQVPDDAVPVGTDESENVERRREGFDSLRSLPDTVIPHYDLGEELEILDFERGA
KVTGGGFYFAKGDGARLEHALVQFMLDIHREQGYQDVFPPIPVNSQSMVGTGQFPKFTEDAYRIGETNDEPWDNDDLWLC
PTAEVPVTNMYRDEILLDDDLPVKIQAYTPNFRREAGEHGTETRGIVRVHQFNKVELVNFVRPEDSAERFDGLLTEAEVV
LQRLGLPYRILEMCTGDLGFTQRKKYDIEVWAPGDDMATGPDIGGRWLEVSSVSNFGAFQSRRAGLRYRPERHESASYLH
TLNGSGVAVPRVMVAIMEYYQNDDGTITIPEPLQPYMNGLSVIEGHDPVGEAAVGAGKRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-80 45