Gene Information

Name : guaA (RD1_2778)
Accession : YP_682995.1
Strain : Roseobacter denitrificans OCh 114
Genome accession: NC_008209
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2648777 - 2650345 bp
Length : 1569 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCACATCTGATCACGACCGCCTTCTTATCATTGATTTCGGCAGCCAGGTGACGCAATTGATTGCGCGTCGCCTGCG
TGAGCTGAATGTCTATTGCGAAATTCACCCCTTTAATCTGGTGGATGACGCCTTTCTGGATGCCTTCGGTGCGAAAGCCG
TGATCTTCTCGGGGGGGCCCTCTTCTGTTTTCGCCGATGGTGCTCCGATGCCCCCGGCCAGCGTCTTTGAGCGCGGTGTG
CCGATCCTGGGCATTTGCTATGGTCAGCAGGTGATGATGCACTGCCTCGGCGGCAAGGTGGAACGCGGGCATGGCACGGC
GGAGTTCGGGCGCGCCTATGTCACCCCGACCGCGCAAAAGCTGGACATGCTGCAGGGGTGGTTTGAAACCGATCAGGACC
GCGAACAGGTCTGGATGAGTCACGGCGATCACGTCAGCCAGATCGCCCCCGGTTTTGAAGTGTTCGGCACCTCGCCCAAT
GCGCCTTTTGCAATCACGGCTGATACAACACGCCATTTCTATGCGGTGCAGTTCCATCCCGAAGTCCACCACACGCCCAA
TGGGGCCAGATTATACGAAAATTTTGTGCGGCTGGCCGGTTTCAAAGGCGATTGGACCATGGGTGCCTACCGCGAGGAAG
CCATCGCAAAGATTCGCGAACAGGTTGGCAGTGGCCGGGTGATCTGCGCCCTTTCGGGCGGCGTTGACAGTTCGGTCGCC
GCCGTTCTGATCCATGAAGCCATCGGGGATCAGCTGACCTGCGTCTATGTGGATCACGGGCTCATGCGCAAAGACGAATC
GGCACAGGTCGTCGGCATGTTCCGTGAACACTACAACCTGCCGCTGATCCATGCGGATGAATCGGACCTGTTTCTGGGCA
AGCTGGAGGGCGTCAGCGACCCCGAAACCAAGCGCAAAATCATCGGCGGTTTGTTCATCGAGGTTTTCGAGAAATACGCG
AAGGAAATCGGCGGTGCCGATTTCCTGGCACAGGGCACGCTCTACCCGGATGTGATCGAATCGGTCAGCTTCTCCGGTGG
CCCTTCGGTCACGATCAAATCGCATCACAACGTCGGCGGGCTGCCGGAGCGGATGAACATGCAACTGGTCGAACCGCTGC
GCGAACTTTTCAAGGATGAGGTGCGCGCGCTGGGTCACGAGTTGGGCCTGCCTGCAAGCTTCATCGGCCGCCATCCTTTC
CCCGGGCCCGGTCTCGCCATCCGCTGCCCCGGCGAGATCACCCGCGAAAAACTCGATATCCTGCGCGAGGCCGATGCCGT
CTATATCGACCAGATCCGTAAACACGGGCTCTACGATGAAATCTGGCAGGCCTTTGTGGCGATCCTGCCCGTGCGCACCG
TGGGTGTGATGGGCGACGGGCGCACCTATGATTTCGCCTGCGCCCTGCGCGCTGTCACATCCGTGGACGGTATGACCGCT
GACTATTATCCCTTCACACATGAGTTTCTCGGAGAGACCGCAACACGCATCATCAACGAGGTGCCCGGCATCAACCGCGT
GACCTACGATATCACCTCAAAACCACCCGGCACGATCGAGTGGGAATAA

Protein sequence :
MSTSDHDRLLIIDFGSQVTQLIARRLRELNVYCEIHPFNLVDDAFLDAFGAKAVIFSGGPSSVFADGAPMPPASVFERGV
PILGICYGQQVMMHCLGGKVERGHGTAEFGRAYVTPTAQKLDMLQGWFETDQDREQVWMSHGDHVSQIAPGFEVFGTSPN
APFAITADTTRHFYAVQFHPEVHHTPNGARLYENFVRLAGFKGDWTMGAYREEAIAKIREQVGSGRVICALSGGVDSSVA
AVLIHEAIGDQLTCVYVDHGLMRKDESAQVVGMFREHYNLPLIHADESDLFLGKLEGVSDPETKRKIIGGLFIEVFEKYA
KEIGGADFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRALGHELGLPASFIGRHPF
PGPGLAIRCPGEITREKLDILREADAVYIDQIRKHGLYDEIWQAFVAILPVRTVGVMGDGRTYDFACALRAVTSVDGMTA
DYYPFTHEFLGETATRIINEVPGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-128 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-128 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-111 49