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Name : YPN_3413 (YPN_3413) Accession : YP_649340.1 Strain : Yersinia pestis Nepal516 Genome accession: NC_008149 Putative virulence/resistance : Virulence Product : two-component sensor/regulator Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0642 EC number : - Position : 3886412 - 3889231 bp Length : 2820 bp Strand : + Note : - DNA sequence : ATGGGCAAAGCATCATCACTTGTCACTCGATTGACATTATTAATGGGCGTCACACTAACTGTTATTTGGTTAATATTAAT CGCAACAACGGCATTCTTTTCATATGAAAATACACGTCAAATATTAATCAATGAGTTAACACATATGGCATCGATGCGGG CGGACTTAAGTAATCACCAGTTTGAAGGAGCTGAACGTGATGCCGCCTCGTTAATAAGCCGACGAGAAAGCCTCCAGAGC ACCTCACCGTTGCCTGAAATATCGATAAAACATTATGATAGCTACTATATTCCCTTTAATCTGGATAGCTGTAATATTAA CCAACATAAAAATGATCTGTGGATAATTCAAGCGTATGGCACCGCCGGACAAACTTATTATCTCGACAGTTTTATTATCA AACAAAAAGAGGGGATTGTGTTATTCCCACCCCAAAAATCATCGAGTGATTACCTAAATCAACGGCGCAAAGATTTACTT TTGCTCCCCAAATTTCCTACTCACAATAATATCTATTGGGGAGCCCCCACCTATACGCCTCAAGGTGGCTGGCATGTTTC TGTCGCGGTGTGTGATAAAGTGGGCACCTTAGCTGGCTTCGCCTTAAAACTGAATGATCTCATCGCCTATAATCACCCTG TCGAGCAAAGAGACATTAATTTATTGTTGGATAAGAATGGTGAATTATTGCCTATTTCCCAGCAAGCAACATCATCAAAT CAACTGCATGAAATTCTTAACCAACTCAAAAACAGTAAATTACACGATGGCTGGCAGCAAACTCCCGACTATTTGGTATT ACGCACCCAATTGAAAGGGCCGGGTTGGCAGCAATTAGTTATTTATCCGCGAATGGGCTTTGCCTGGGAGGCACTGAAAC CCGCCTTATATCAACTCCCTTTCGCTCTGGCTATTTTACTGTTGCTCACGTCAGTACTGTCACTGCTGCTGCGATATTAT CTGGCGATCCCTTTGTGGAATTTCATCAATATCATTGGCGCTACCGGGCCACAGGCAATGGAACCCCGACTTCCCATAAA CCGAATAGATGAATTAGGGCATATTGCCCGCGCTTATAACAACTTACTGGATACGTTGAACGAACAATATGACACCTTAG AAATGAAAGTGAAGGAGCGCACTCTGGCTCTGGCGGAAGCCAAGCGAGCGGCTGAGCAGGCTAACCGCCGTAAAAGCGAC CATCTGACCACGATCAGCCATGAAATCCGTACACCGCTCAACGGGGCGTTGGGGGCGGTTGAATTATTACAAAATACACC ACTGGATGCTGGCCAAATGAGGTTAGCGGAAACGGCCCACCAATGTTCGTTGTCACTGCTCGCGATCATTAACAACCTGT TAGATTTTTCACGTATTGAATCAGGGCAGATGACACTGTCGCTGGAGAAAACGGCCCTACTGCCTTTACTGGATCAGGCG ATGTTAACCATTCATAGCCAGGCACTGAGTAAGTCATTAGCGCTGTCCACGTTTATCAGTGCCAATATCCCGCTGGAACT TGAGCTGGATACACTGCGCTTAAGACAGATTCTGGTTAATTTATTAGGTAATGCCGTTAAATTCACACCACAGGGCCGTA TTCAACTCAGGGTCAGGCGTCAAAACCAAACGCTTTGTTTTACCGTTGAGGACACCGGTTGTGGTATTGACGTGCAACAC CAACAAACAATATTCCAACCTTTTATGCAGACCAGTGACCATGAACAAGGAACGGGTTTGGGGCTGGCTATCGCAGATAA TCTGGCCAAAATGATGGGAGGGCACCTGACAGTATTCAGTGAACCGGGTCAAGGTAGCTGTTTTTCATTATGCCTCCCCT TCAATGCAATCACCCCGCCAATGCCTTTTCATGGCGAGCTATTCGCACCACAACGCTTACACGCCCAATTATCAGCCTGG GGCATGACCTGCCAGCCAGAATTAGCTAATCAGCCATCACGGCACTTTGTGGATAACGCATTGTGTTACTTACCCGGCCG GTTATACGCCAAGCTGAAACAATATCTACAAGGTGCTGAGACTGAAGCGCTAAAGAGCCTTCCGCTGCAACCTTGGCAGA TGCACATTCTATTGGTTGATGACTCCGAAACTAATCGCGATATTACCGGAATGATGTTGCAGCAACTGGGGCATCAGGTC ACGCGGGCAGACAGTGGCACAACCGCATTGGCGATTGGCCGCCAACACCGTTTCGATTTAGTGCTAATGGATATTCGAAT GCCTGTCCTGGACGGGCTGGCCACCACAGCACGCTGGCGTCATGATCCGGCGAACATTGATAGCCACTGCATGATCACCG CCCTGAGCGCCAATGCCAGCCCGGATGAGCAAATCAAAACCAGTCAGGCGGGGATGAATCACTACCTTTCCAAGCCTGTC ACCCTCGGCCAATTGGCTGAAATGTTAGATCTGACCGCACAATTCCAGCTTGAGCGTGGGGTCGATCTATCACCACAACT CTCCGAGCCTCAGCCATTACTGGATCTCGCGGACAGCGCGTTGTCCCTGAAACTTTATCAATCACTGCAAGTATTAATTC AACAGGCCAAAGACGCTATTGAGAACTTGCCCGTATTATCCCATACGCTTCACACCATAAAAGGCTGTGCCGGGCAAGCT GGGCTAATTGAATTACAAGATGCGGTCATTCAATTAGAACACGCTCTCGATACTCATGAAACGCTGACACAGCAAGAGAT CATTCAACTTGATGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCC AGTCCCTTATGGTTAAATAA Protein sequence : MGKASSLVTRLTLLMGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQS TSPLPEISIKHYDSYYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYLDSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLL LLPKFPTHNNIYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVEQRDINLLLDKNGELLPISQQATSSN QLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRMGFAWEALKPALYQLPFALAILLLLTSVLSLLLRYY LAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAEAKRAAEQANRRKSD HLTTISHEIRTPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQA MLTIHSQALSKSLALSTFISANIPLELELDTLRLRQILVNLLGNAVKFTPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQH QQTIFQPFMQTSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFNAITPPMPFHGELFAPQRLHAQLSAW GMTCQPELANQPSRHFVDNALCYLPGRLYAKLKQYLQGAETEALKSLPLQPWQMHILLVDDSETNRDITGMMLQQLGHQV TRADSGTTALAIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDSHCMITALSANASPDEQIKTSQAGMNHYLSKPV TLGQLAEMLDLTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQSLQVLIQQAKDAIENLPVLSHTLHTIKGCAGQA GLIELQDAVIQLEHALDTHETLTQQEIIQLDEIIHVLLQPPTTCESTFIISQGQSLMVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| YPO0256 | YP_002345336.1 | two-component sensor/regulator | Not tested | Not named | Protein | 0.0 | 100 |
| spiR | AAC44299.1 | SpiR | Virulence | SPI-2 | Protein | 3e-145 | 47 |
| ssrA | NP_456136.1 | putative two-component sensor kinase | Virulence | SPI-2 | Protein | 7e-153 | 45 |
| ssrA | NP_805063.1 | two-component sensor kinase | Virulence | SPI-2 | Protein | 2e-153 | 45 |
| ssrA | NP_460357.1 | sensor kinase | Virulence | SPI-2 | Protein | 4e-152 | 45 |
| ssrA | YP_216400.1 | secretion system regulator:sensor component | Virulence | SPI-2 | Protein | 6e-153 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| YPN_3413 | YP_649340.1 | two-component sensor/regulator | VFG0493 | Protein | 2e-152 | 45 |
