Gene Information

Name : YPN_2508 (YPN_2508)
Accession : YP_648436.1
Strain : Yersinia pestis Nepal516
Genome accession: NC_008149
Putative virulence/resistance : Virulence
Product : ATPase subunit of ATP-dependent protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2817901 - 2820543 bp
Length : 2643 bp
Strand : -
Note : -

DNA sequence :
ATGACAACGCATTCAGCACACTTATTACGTCGGTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCCGCCACCCTGTG
TCAGACCCGCGCCCATGCTGAGATCACTGTCGAACACTGGTTGTTAAAATTGCTGGAGCAGGGCGAAGGCGATATTACAG
TCATTGCCCGGCGTTATGAGTGGGACATGGACAGCCTGTGGCAGGGATTACTGTCCCATCTGGACACCTTGCCGCGCACG
GTACAGGGCAAACCTCAGTTGTCCGCCGCGTTACAGCAACTGATCAAAAACGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATTGCCACGCCGTCATTATTGGTCGCCGAGGCCGCCTGGC
CGTTGCTCAGCCTGAGCACCACTCAGCTACAGCGCCTGTTACCGCTGCTGGACAACCAGTCCGACGAACGCCCTGAGGTG
CAGCAGGCTGCGGCACTGGCCGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTCACCCTCGACGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ACCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTCTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCGCTGGTTGAAGGGCTGGCACTGCGGATTGCCGACGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGGGCTGGGGTGAAAGGCGAATTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCTGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAG
TGGACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCAT
ATTCTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTTCTGACCGGTCGCCAACTGCCGGACAAAGCGGT
GGATCTTCTCGACACCGCAGGTGCGCGCGTGCGCATGAGCATCGACACCTTGCCGACTGCGTTGATGGAGATTAACGCCG
AACTGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACTTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTA
CCTGAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAGAAGCGGTT
GACCACCCTGATTATTGAGGCGCGTCAGGACATCGCCAACGCAGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGA
TTCAGGGCAATGCGCCGCTGTTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGTGTG
CCGCTGGGCAGTTTACTCAAAGACGAACAAACCAACTTGCTGTCACTGGAAAATCGTCTGGGTGAGCGAGTGATTGGGCA
GGATGCGGCATTAGGTGCGCTGGCGCAACGGCTGCGGGCCGCCAAAACCGGCCTGACATCAGAGAATGGCCCGCTGGGGG
TGTTCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGTTGGCACTGGCCGACAGCCTGTTCGGCGGGGAA
AAATCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCGCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCGGGTTA
TGTCGGTTACGGACAGGGCGGCGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGG
AAAAAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAA
ATTGATTTCCGCAACACGGTCATTGTGATGACCGCCAATCTGGGCAGTGATCATCTGATGCAGTTGCTGGATGAGCAACC
GGACGCGCCGGACAGCACCCTGCATGAACTGCTGCGGCCGATCCTACGCGACCACTTCCAGCCCGCGCTGCTGGCCCGCT
TCCAGACCTTGATTTACCGCCCGCTTCAGGTGGATGCGCTCAAACGCATTGTGGCGATAAAACTGAATCAGGTGGCGCAA
CGCCTGCACTGTCACTACGGCCTGAGCTGCCAGATTGAAGACAGCCTGACCGACACACTGGTCGCCGCCTGCCTGCTGCC
GGACACCGGCGCACGCAACATCGACAGCCTGCTCAATCAGCAGATTTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCA
TGAGCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGCATGAAGAAGATGGCATCACGCTGACATTTGAGGGCGAA
TAA

Protein sequence :
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLSHLDTLPRT
VQGKPQLSAALQQLIKNAWLDASLQENADAVRSVHLMAALIATPSLLVAEAAWPLLSLSTTQLQRLLPLLDNQSDERPEV
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIADGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMEINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANAAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLGSLLKDEQTNLLSLENRLGERVIGQDAALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVIVMTANLGSDHLMQLLDEQPDAPDSTLHELLRPILRDHFQPALLARFQTLIYRPLQVDALKRIVAIKLNQVAQ
RLHCHYGLSCQIEDSLTDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWHEEDGITLTFEGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-130 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPN_2508 YP_648436.1 ATPase subunit of ATP-dependent protease VFG2076 Protein 7e-147 44
YPN_2508 YP_648436.1 ATPase subunit of ATP-dependent protease VFG2084 Protein 4e-130 43