Gene Information

Name : fliP (YPN_2303)
Accession : YP_648231.2
Strain : Yersinia pestis Nepal516
Genome accession: NC_008149
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 2584461 - 2585201 bp
Length : 741 bp
Strand : +
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :
ATGTCGGTTATCAATAAAACCACACTGGGGCTGCTCACCTTATTTTGCTCGCCTTCGGTATTGGCTCAACTGCCTGGGAT
CATCAGCCAACCGTTGGCTAATGGTGGACAGAGTTGGTCTTTACCCGTGCAAACGCTGGTGTTCATCACCACGCTGAGTT
TTTTGCCCGCGGCGTTACTGATGATGACCAGTTTTACCCGCATCATTATTGTGCTCGGGTTACTGCGTAACGCGATGGGC
ACCCCTTCGGCCCCGCCGAATCAGGTGATGCTGGGGCTGGCACTGTTTCTGACCTTTTTTATTATGTCACCGGTGTTTGA
CAAAGTGTATCAAGAGGCTTATCTGCCCTTCAGTCAGGATAAAATCAGCATGGACGTGGCGTTGGATAAAGGCTCACAAC
CGTTGCGGGAGTTTATGCTGCGCCAAACGCGGGAATCTGATCTGGCGCTGTATGCCCGGTTGGCAAACCTGCCGCCGCTG
GAAGGCCCCGAAATGGTTCCGATGCGTATTCTGCTGCCCGCCTATGTCACCAGTGAGTTGAAAACGGCATTCCAAATTGG
TTTTACCGTATTTATTCCGTTCCTGATTATCGATTTGGTGGTCGCCAGTGTGCTGATGGCGCTGGGGATGATGATGGTTC
CGCCTGCCAGTATCTCGCTACCGTTCAAGCTGATGCTATTTGTTCTGGTTGATGGCTGGCAATTGTTACTGGGTTCACTG
GCACAGAGTTTTTATAGCTGA

Protein sequence :
MSVINKTTLGLLTLFCSPSVLAQLPGIISQPLANGGQSWSLPVQTLVFITTLSFLPAALLMMTSFTRIIIVLGLLRNAMG
TPSAPPNQVMLGLALFLTFFIMSPVFDKVYQEAYLPFSQDKISMDVALDKGSQPLREFMLRQTRESDLALYARLANLPPL
EGPEMVPMRILLPAYVTSELKTAFQIGFTVFIPFLIIDLVVASVLMALGMMMVPPASISLPFKLMLFVLVDGWQLLLGSL
AQSFYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 2e-27 45
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 2e-27 45
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 2e-27 45
hrcR ABA47279.1 HrcR Virulence S-PAI Protein 6e-28 44
hrcR BAB07862.1 HrcR Virulence Hrp PAI Protein 2e-31 41
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 2e-32 41
hrcR ABQ88359.1 HrcR Virulence Hrp PAI Protein 2e-20 41
hrpW AAB05075.1 HrpW Virulence Hrp PAI Protein 2e-20 41
XC_3016 YP_244084.1 type III secretion system protein Virulence Hrp PAI Protein 8e-33 41
hrcR NP_636600.1 type III secretion system protein Virulence Hrp PAI Protein 8e-33 41
hrcR AAT96200.1 HrcR Virulence T-PAI Protein 2e-21 41
hrcR AAT96146.1 HrcR Virulence T-PAI Protein 2e-21 41
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-27 41
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_648231.2 flagellar biosynthesis protein FliP VFG2338 Protein 2e-100 97
fliP YP_648231.2 flagellar biosynthesis protein FliP VFG2494 Protein 5e-73 68
fliP YP_648231.2 flagellar biosynthesis protein FliP VFG1259 Protein 7e-61 57
fliP YP_648231.2 flagellar biosynthesis protein FliP VFG2016 Protein 2e-60 56
fliP YP_648231.2 flagellar biosynthesis protein FliP VFG0188 Protein 1e-30 43