Gene Information

Name : YPN_1847 (YPN_1847)
Accession : YP_647776.1
Strain : Yersinia pestis Nepal516
Genome accession: NC_008149
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2088017 - 2089429 bp
Length : 1413 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGAAAAAGACTAAAATTGTTTGTACTATCGGTCCAAAAACCGAATCCGAAGAAATGCTGACAAACCTGCTGAATGCTGG
CATGAACGTTATGCGTTTAAACTTCTCTCACGGTGACTATGCAGAGCACGGTCAACGTATCAAAAACCTCCGGGCTGTAA
TGGCAAAAACAGGCAAAAAAGCCGCGATTTTGCTGGATACTAAAGGCCCTGAAATCCGGACCATGAAACTGGAAGGCGGC
AAAGATGCTGCGCTGGTTGCAGGTCAGACCTTCACGTTCACGACTGATCAAAGCGTTGTCGGTAACGACAAAATTGTTGC
AGTCACCTACCCAGGCTTCGCCGCTGACCTGAAAATTGGTAACACTGTTCTGGTTGACGATGGCTTGATCGGTATGGAAG
TCATTGAAGTCACTGAACACACCGTTGTCTGTAAAGTCTTGAACAGTGGTGATTTGGGTGAAAACAAAGGCGTTAACCTG
CCAGGCGTGTCGATCCAACTGCCCGCATTAGCAGAAAAAGATAAAGGCGACCTGATCTTCGGTTGCGAACAAGGCGTTGA
TTTCGTTGCCGCCTCCTTTATCCGTAAACGTTCTGATGTACTGGAAATTCGTGAACACCTGAAAGCACACGGTGGCGAAC
ATATCCAGATCATCTCTAAAATCGAAAATCAGGAAGGTCTGAATAACTTCGACGAAATCCTGGAAGCCTCTGACGGTATC
ATGGTTGCCCGTGGTGACTTAGGTGTTGAGATCCCTGTCGAAGAAGTCATCTTCGCGCAGAAGATGATGATCGAGAAATG
TAACCGCGCACGTAAAGTTGTTATTACTGCAACTCAAATGCTCGATTCCATGATCAAAAACCCACGTCCTACCCGCGCAG
AAGCCGGTGACGTTGCAAACGCCATCCTTGACGGTACCGACGCGGTCATGCTGTCCGGCGAAAGTGCTAAGGGTAAGTAC
CCATTAGAGTCTGTCACCATCATGGCGACCATCTGTGAGCGTACAGACCGTGTTATGCCTAGCCGCATTGAGTCACTGAA
CGACAACCGTAAAATGCGAATCACTGAAGCCGTTTGCCGTGGTGCTGTTGAAACCGCAGAAAAACTGGAAGCCAAAGTGA
TTGTGGTCGCAACCGGGGGGGGTAAATCTGCAAAATCTGTCCGTAAATACTTCCCTACTGCGACCATTCTGGCACTGACG
ACCAATGAAATGACAGCCCATCAGTTAATTCTGACTAAAGGCGTAATCACTCAGTTGGTAGACGAAATCGCCTCAACCGA
TGATTTCTACCGTCTCGGTAAAGAAGCGGCTCTGGCGAGCGGCCTGGCACAGAAAGGCGACGTGGTCATCATGGTTTCAG
GTGCCTTGGTACCAAGCGGTACGACCAATACCTCTTCAGTACACGTGTTATAA

Protein sequence : 
MKKTKIVCTIGPKTESEEMLTNLLNAGMNVMRLNFSHGDYAEHGQRIKNLRAVMAKTGKKAAILLDTKGPEIRTMKLEGG
KDAALVAGQTFTFTTDQSVVGNDKIVAVTYPGFAADLKIGNTVLVDDGLIGMEVIEVTEHTVVCKVLNSGDLGENKGVNL
PGVSIQLPALAEKDKGDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGEHIQIISKIENQEGLNNFDEILEASDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY
PLESVTIMATICERTDRVMPSRIESLNDNRKMRITEAVCRGAVETAEKLEAKVIVVATGGGKSAKSVRKYFPTATILALT
TNEMTAHQLILTKGVITQLVDEIASTDDFYRLGKEAALASGLAQKGDVVIMVSGALVPSGTTNTSSVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 87
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 87
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 87
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 87

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPN_1847 YP_647776.1 pyruvate kinase VFG0479 Protein 0.0 87