Gene Information

Name : hemC (YPN_0114)
Accession : YP_646047.1
Strain : Yersinia pestis Nepal516
Genome accession: NC_008149
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 153106 - 154047 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACACGACAAAGCCCGCTCGCCTTATGGCAAGCACATTATGTTCAACATTTATT
GCAAGCCAATCACCCTGGTCTGCAAATCGAACTGGTCCCAATGGTCACCCGTGGGGATATCATTTTGGATACACCATTGG
CCAAAGTCGGTGGTAAGGGTTTATTTGTCAAAGAATTAGAGCTGGCGCTGCTGGACGGCAGAGCTGATATTGCCGTGCAT
TCGATGAAAGATGTGCCCATTGCTTTCCCCGAAGGGCTGGGTTTAGTCACGATTTGTGAACGTGAAGACCCGCGCGATGC
TTTCGTCTCGTCACATTATGCCCATCTGGATGATCTCCCTGCAGGCAGTGTTGTCGGTACCTCCAGCCTGCGCCGCCAGT
GTCAGCTACGCGAACGGCGACCAGACCTGATTATCCGCGATCTACGGGGCAACGTCGGTACCCGCCTTGCCAAACTGGAT
AATGGTGACTATCAGGCTATTATTCTGGCTGTCGCGGGTCTCAAGCGCCTCGGTCTGGAAAACCGAATTCGCTATGCCAT
GTCAGCGGAGGAGTCCCTCCCGGCTGTCGGCCAAGGTGCCGTAGGTATCGAATGCCGTCTGGATGATGACCATACCCGCC
AGTTGCTGGCTCCGTTGAACCATCGGCACACCGAATTACGGGTCTGTGCGGAGCGGGCAATGAATATTCGCCTTGAAGGG
GGTTGCCAAGTCCCGATCGGTAGCTACGCTGAACTGGAAGGTGATACTTTATGGCTACGGGCGCTGGTGGGAGCACCTGA
TGGCAGCCAAATGATCCGGGGTGAACGCCGTGGTCCGGCGGCAGAGGCTGAGCAGATGGGCATTGAACTTGCCGATGAGT
TGCTATCACGCGGCGCACGAGAAATCCTGGCGGCGGTTTATCTGGATAATCCTGCGCGATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVH
SMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLD
NGDYQAIILAVAGLKRLGLENRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEG
GCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-83 62
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-83 62