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Name : Rxyl_1767 (Rxyl_1767) Accession : YP_644538.1 Strain : Rubrobacter xylanophilus DSM 9941 Genome accession: NC_008148 Putative virulence/resistance : Resistance Product : mercuric reductase MerA Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : - Position : 1794597 - 1796243 bp Length : 1647 bp Strand : + Note : TIGRFAM: Mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region Heavy metal transport/detoxification protein; KEGG: gka:GK3096 mercuric reductase DNA sequence : TTGAGCGGTCACAGGTCGAGGATGAAGGTCGGGGGCATGACCTGCGGCCACTGCGAGGTCGCCGTCGGGCGGGCGCTGGA GGGCGCCGGGGCCCGCGACGTCGAGGCGGACTTCCGGCGCGGGGAGGCGGTCTTCGCGCTCCCGGAGGGTGCGGGCGTGG AGGCCCTCCGCCGGGCGGTGCGGGAGGCCGGCTACGAGCCGGGGGCGGTCGAGCGGGTCGGGGGGGAGCGCGTGCGCGGC GGGGGCAGGCACGACTACGACCTGGCGATCATCGGCTCGGGCGGCGGGGCGTTCGCGGCGGCGATCCGGGCCGTCGAGAG GGGGGCGCGGGTCGCCATGATCGAGCGCGGCACCGTCGGCGGCACGTGCGTGAACGTCGGGTGCGTGCCCTCCAAGACGC TGTTGCGGGGGGCCGAGATTTACCACCGGGCCGGCCACCACCCCTTCGAGGGGGTAAGGACGAAGGCGCTCGCGGCCGAC TACGGGGCGATGGTCGCCCAGAAGGACCGGCTCGTGGGGCGCATGCGGCAGGAGAAGTACCTGGACCTCGTGGAGGAGTA CGGGTGGGAGCTCATCCGGGGCGAGGCCGCCTTCGAGGACGAGGGGACGCTGCGCGTTGAGGGCCGCAGGATAAGCGCCG CCGCCTACCTCATAGCCACGGGCGCCCGTCCCGCCGTGCCGCCCATCCCCGGTCTCGAGGAGGCCGGCTACCTCACCAGC ACCACGAACATGGAGCTCGAGGAGGCGCCGGAGTCGGTGCTCGTGATCGGGGCCGGGTACGTGGCCATCGAGCAGGGCCA GCTCCTTTCTCGCCTCGGGAGCAGGGTGACCCTCATGCAGCGCGGCCCGAGGCTGCTGCGCGAGCAGGAGCCCGAGGTCT CGGAGGCGATGATGGAGGCGCTCCGGCGCGAGGGCATCGAGGTCCTCACCGGGGTGCGCATCGAGCGCGCCGGGAAGACG GAGAAGGGCAAGAAGCGCCTCCACCTCGCCGTGGGCGGCGAGGAGCGGGTGCTGGAGGGTGAGGAGATCCTGGTCGCCGC GGGCCGCAGGCCCAACGTCGAGGAGCTTGGCCTGGAGCGGGCCGGCGTAGAGCTCGACGAGCGCGGAGCCGTGCGGGTGG ACGGGCGGCTCGGGACCACCAACCCGAGGGTGTGGGCCGCGGGCGACGTCACGCTCGGGCCGCAGTACGTCTACGTCGCG GCCTACGAGGGCGCTCTCGCCGCGGACAACGCGCTCGGCGGGGCGGGCAGGGAGGTGGACCTCAGCGCGCTCCCCGGCGT GATCTTCTCCGACCCCCAGGTCGCGAGCGTCGGGCTCACCGAGCGGAGAGCCCGGGAGAGAGGGCTCGAGGTCCAGAGCT CCGTGCTGCCGCTGGAGGCGGTGCCCCGCGCGCTCGTAAACCACGACACTCTAGGGGTCATAAAGCTCGTCGCCGAGGCG GGGACGGGGCGGCTGCTCGGGGCGCACATGGTCGCCGAGAACGCGGGGGACGTGATCTACGCCGCCACCCTCGCCGTCAG GTTCGGCCTCACCGTCTCCGACCTCGCGGAGAACTTCGCCCCCTACCTGACGATGTCCGAGGGCCTCAAGCTCGCCGCCC AGGCCTTCGGGCGCGACGTCTCCAGGCTCTCGTGCTGCGCGGCGTAA Protein sequence : MSGHRSRMKVGGMTCGHCEVAVGRALEGAGARDVEADFRRGEAVFALPEGAGVEALRRAVREAGYEPGAVERVGGERVRG GGRHDYDLAIIGSGGGAFAAAIRAVERGARVAMIERGTVGGTCVNVGCVPSKTLLRGAEIYHRAGHHPFEGVRTKALAAD YGAMVAQKDRLVGRMRQEKYLDLVEEYGWELIRGEAAFEDEGTLRVEGRRISAAAYLIATGARPAVPPIPGLEEAGYLTS TTNMELEEAPESVLVIGAGYVAIEQGQLLSRLGSRVTLMQRGPRLLREQEPEVSEAMMEALRREGIEVLTGVRIERAGKT EKGKKRLHLAVGGEERVLEGEEILVAAGRRPNVEELGLERAGVELDERGAVRVDGRLGTTNPRVWAAGDVTLGPQYVYVA AYEGALAADNALGGAGREVDLSALPGVIFSDPQVASVGLTERRARERGLEVQSSVLPLEAVPRALVNHDTLGVIKLVAEA GTGRLLGAHMVAENAGDVIYAATLAVRFGLTVSDLAENFAPYLTMSEGLKLAAQAFGRDVSRLSCCAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 4e-125 | 56 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 3e-125 | 56 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 1e-60 | 45 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 2e-62 | 45 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 2e-62 | 45 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 2e-62 | 45 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 2e-61 | 44 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 3e-59 | 44 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 2e-59 | 44 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 2e-59 | 44 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 3e-61 | 44 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 1e-63 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Rxyl_1767 | YP_644538.1 | mercuric reductase MerA | BAC0651 | Protein | 2e-125 | 56 |
| Rxyl_1767 | YP_644538.1 | mercuric reductase MerA | BAC0224 | Protein | 3e-119 | 55 |
| Rxyl_1767 | YP_644538.1 | mercuric reductase MerA | BAC0650 | Protein | 4e-60 | 45 |
| Rxyl_1767 | YP_644538.1 | mercuric reductase MerA | BAC0653 | Protein | 7e-63 | 43 |
| Rxyl_1767 | YP_644538.1 | mercuric reductase MerA | BAC0652 | Protein | 3e-63 | 43 |
