Gene Information

Name : lysS (Mmcs_4758)
Accession : YP_641918.1
Strain : Mycobacterium sp. MCS
Genome accession: NC_008146
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 5035062 - 5036600 bp
Length : 1539 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGACACCGACCGGCGGCGACAACACGCCCGAGAACAACGCGCCCGATAACGACCCTGACATCCCCGAGCAGTTCCGCAT
TCGTCAGGCCAAGCGGGAACGTCTGCTGGCCGAGGGTCGCGACCCCTACCCGGTGGACGTGGACCGCACGCACACGCTCG
CCGAAGTGCGCGCCGCTTTCCCCGACCTGCCGGTCGACTCGCAGACCGGCGAGATCGTCGGCGTCGCCGGGCGCGTCGTA
TTCGCCCGCAACTCGGGGAAGCTGTGTTTCGCGACCTTGCAGGAGGGCGACGGTACGCAACTACAGGCCATGATCAGCCT
GGCCGAGGTGGGGCAGGAATCGCTCGACAGCTGGAAAGCCGACGTCGACCTGGGTGACATCGTGTCCGTCCACGGCCAGG
TCATCAGTTCCCGTCGCGGTGAGCTCTCTGTGCTCGCCGATTCCTGGCAAATCATCTCCAAGGCGCTGCGGCCGCTTCCG
GTCGCGCACAAGGAGATGAGCGAGGAGGCACGGGTGCGGCAGCGCTACGTCGACCTCATCGTGCGTCCGGAGGCCCGCAC
CATCGCACGTCAACGCGTGGCCGTCGTGCGTGCGCTCCGCAACGCGCTCGAGCGGCGCGGCTTCCTCGAACTCGAGACGC
CGATGCTGCAGACCCTGGCCGGCGGTGCGGCGGCCAGGCCGTTCGTCACCCACTCCAATGCACTCGATGTGGACCTATAC
CTGCGTATCGCGCCGGAGCTGTTCCTCAAGCGTGCCCTGGTCGGTGGTTTCGAGAAGGTCTTCGAGCTGAATCGCAACTT
CCGAAACGAAGGTATCGATTCCACGCATTCTCCCGAATTCGCGATGCTGGAGACTTATCAGGCGTATGGCGACTACAACG
ATTCCGCGGTCGTGACGCGGGAACTAATTCAGGAAGTCGCCGACGAGGCGATCGGGACCCGTCAAGTGCCATTGGCGGAT
GGCACCGTGTACGACCTGGACGGTGAGTGGGAGTCGTTGGAAATGTACCCCTCGCTGTCCGCGGCGCTGGGTGAGGAGAT
CACCCCGCAGACCCCCGCCGACGAACTCTGGCGGATCGCCGACCGGCTCGGTGTGGAGATTCCCCGTGACCGCGGATACG
GCCACGGGAAATTGATCGAGGAACTGTGGGAGCACACCGTCGGCGAGGATCTCTGGGCGCCGACCTTCGTGCGGGACTTC
CCGGTGGAGACGACCCCGCTCACCCGGTCGCACCGCAGCGTTCCCGGCGTCACCGAGAAGTGGGATCTCTATGTCCGCAA
GTTCGAGTTGGCGACCGGCTATTCCGAACTCATCGATCCGATAATTCAGCGCGAGCGATTCGAGGAGCAGGCGCGAGCGG
CCGCTGCCGGTGACGACGAGGCAATGGTTCTCGACGAGGATTTCCTGGCGGCATTGGAGTACGGCATGCCGCCGTCCACC
GGTACCGGAATGGGCATCGACCGGTTGCTGATGGCGCTGACTGGACTGTCAATTAGAGAGACAATTCTCTTCCCGATTGT
TCGGCGGCACGGCGGCTGA

Protein sequence :
MTPTGGDNTPENNAPDNDPDIPEQFRIRQAKRERLLAEGRDPYPVDVDRTHTLAEVRAAFPDLPVDSQTGEIVGVAGRVV
FARNSGKLCFATLQEGDGTQLQAMISLAEVGQESLDSWKADVDLGDIVSVHGQVISSRRGELSVLADSWQIISKALRPLP
VAHKEMSEEARVRQRYVDLIVRPEARTIARQRVAVVRALRNALERRGFLELETPMLQTLAGGAAARPFVTHSNALDVDLY
LRIAPELFLKRALVGGFEKVFELNRNFRNEGIDSTHSPEFAMLETYQAYGDYNDSAVVTRELIQEVADEAIGTRQVPLAD
GTVYDLDGEWESLEMYPSLSAALGEEITPQTPADELWRIADRLGVEIPRDRGYGHGKLIEELWEHTVGEDLWAPTFVRDF
PVETTPLTRSHRSVPGVTEKWDLYVRKFELATGYSELIDPIIQRERFEEQARAAAAGDDEAMVLDEDFLAALEYGMPPST
GTGMGIDRLLMALTGLSIRETILFPIVRRHGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-145 64