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Name : lysS (Mmcs_2983) Accession : YP_640146.1 Strain : Mycobacterium sp. MCS Genome accession: NC_008146 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 3147661 - 3150999 bp Length : 3339 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGACGCTCACCAGTCCGCCGAGGACTCGCGCCGACTCCCGCTACTCCTGGGTTCCCGCGGCCGCCGGATGGACCGTCGG CGTCATCGCCACCCTATCGCTCATCGCGAGCGTCTCGCCGCTGGTCCGGTGGATCATCCGGGTGCCGCGAGAGTTCGTCG ACGACTACATCTTCAACTTCCCCGACACCAGCTTCGCCTGGGCGTTCGTGCTGGCGCTGCTGGCGGGCGCGCTGGCCGCC CGCAAACGCATCGCCTGGTGGATTCTGCTGCTGTACATGGTGGCCGCGGCCGGCTGGAACGTCGCCGATCTGCTGACCGG TGACGAATCGGTCGTCGACGAGATGGGCGAGGTCATCGGCCTCGCCTTCCACCTTGCAGCCGTGGCCTTCCTGTTGTTGG CCCGCCCGCTGTTCTGGGCCCGCGTGCGGCGCGGCGCCCTGTTCAAGGCGGCCGGTGTGCTGGCCGCCGGAATGGCGGTC GGCGTGCTCGTCGGCTGGGGGCTGCTCGAACTGTTCCCCGGCGACCTCGAACGCGACTACCGGTTGGCATACGCGGCGAA CCGGGTGTTCGCGTTCGCCGGAGTGGACCCCGACGCGTTCGACGGACAACACCCACACGTGGTCGTCAACGCGCTGCTCG GGTTGTTCGGCGCGCTGGCGCTGATGGCCGCGGCGATCGTGCTGTTCCAGTCGCAGCGTTCGGAGAACGCGCTCACCGGC GAAGACGAATCGGCCATCCGCGGTCTGCTCGAGCTCTACGGCAAGAACGACTCGCTGGGCTACTTCGCCACCCGGCGGGA CAAGTCCGTGGTGTTCGCACCGAACGGACGTGCCGCGATCACCTACCGGGTCGAAGTGGGGGTCTGCCTGGCCAGCGGTG ACCCGGTCGGCGACCCGAAGGCCTGGCCGCAGGCGATCGACGCGTGGCTGGCGCTGTGCGGGACGTACGGCTGGGCACCG GGCGTCATGGGTGCCAGCGTGGGCGGGGCCGAGGCGTTCCGGGCGGCCGGACTCAGCGCGATCCAACTGGGCGACGAGGC CATCCTGCTTCCGGACAGCTTCCGGCTCTCCGGGCCGGACATGCGGGCTGTGCGCCAGGCCGTCACGCGGGCCCGCCGCG CCGGGGTGACCGTGCGGATCCGCAGACACCGCGAGCTCTCACCCGAACAGATGGCCGAGGTGATCGCCCACGCCGACGCG TGGCGCGACACGGAGACAGAACGCGGCTTCTCGATGGCGCTCGGCCGCCTCGGCGATCCCGCCGACAGCGACTGTCTGCT GGTGGAGGCCGTCCAGGGCGGGAACGGCGGGCAGGAGCGAAGCGACCCGGGGGATGGCACTGTCGTGGCCATGCTGTCGT TGGTTCCGTGGGGCAGCAACGGCGCCTCCCTCGACGTGATGCGGCGTTCCCCGCAGTCACCCAACGGCACCATCGAGTTG ATGGTCAGCGAGCTGTGCATGCAGGCCGAGGACATCGGCGTCACCCGCATCTCCCTGAACTTCGCGATGTTCCGGTCGGC GTTCGAGCAGGGCGCGCAACTCGGCGCCGGACCCGTGGCCCGGCTGTGGCGCTGGCTGCTGGTCTTCTTCTCCCGGTGGT GGCAGCTGGAGACGCTGTACCGCTCGAACATGAAATACCAACCGCAGTGGGTGCCGCGCTACGCGTGCTACGAGGATGCG CGCCTCATCCCCCGCGTCGGGGTGGCGTCGGTGATCGCCGAGGGCTTCCTGGTGCTGCCGTTCTCGCGGCGCAACAAACA ACACACCGGCCACCACACGTCCGCACCGCAGGACCTGGTCGCCAGCGGCGTGCTCCACCACGACGGCACCGCACCCGACA TGTCCGGGTTGCGCACCGACACCGCCGACGACGAACCGCCCCGGTTGCCCGAGCAGGTGCGGGTCCGGATGGCGAAACTC AAGGCGCTGCAGGCCGACGGCGTCGACGCCTATCCGGTCGGTCGGCCACCGAGCCACACCGCGGCGGCTGCCGTCGACTC CCCCGACGACGTCGAACTCGATGTCGCCGGCCGGGTGCTGCGCATCCGCGACTACGGCGGTGTGCTGTTCGCCCAGTTAC GGGACTGGTCGGGTGAAGTGCAACTGCTGCTGGACAATTCGACACTCGAGCAGGGCAGCACCGCCGACTTCACCGCGGCC ATCGACCTCGGCGACCTCATCGCGGCGACCGGCACCATGGGCTACAGCAAGAATGGGACCCGCTCGCTGCTGGTGCGGCA CTGGCGACTCACCGGTAAATGCCTGCGTCCCCTGCCGGACAAGTGGAAGGGCCTGACCGATCAGGAGGCCCGCGTCCGGG CCCGCTACGTCGACCTGGCGGTCAACACCGAGGCGCGGGATCTGATCCGGGCCCGCAGCGGCGTGCTGCACGCGATCCGG GACACGCTGTACCACAAGGGTTTTCTCGAGGTCGAGACCCCGATCCTGCAGCAGATCCACGGCGGCGCCAACGCACGGCC GTTCCTGACCCACATCAACGCCTACGACCTGGACCTGTATCTGCGCATCGCGCCCGAGCTGTATCTCAAGCGGCTCTGCG TCGGTGGAGTGGAGCGAGTCTTCGAACTCGGCCGCGCGTTCCGCAACGAAGGCGTCGACTTCTCTCACAACCCCGAATTC ACACTGCTGGAGGCGTATCAGGCGCACGCCGACTACCACGTGTGGATCGACGGGTGCCGTGAACTCATCCAGAACGCCGC GATGGCCGCCAACGGTGAGCACGTGTTCCTCCGCCCGCGTGACGACGGCGTCCTCGAACCCGTCGACATCTCCGGACCGT GGACCGTCAAGACCGTCCACGAGGCGGTGTCCGAGGCGCTGGGCGAACACATCGACGCCGCCACGGAACTGCCGACGCTG CGCAAGCTGGCCGACGCGGCGGGCATCCCCTACCTGACCCACTGGGACGAGGGGGCGGTGGTGCTCGAGATGTACGAACA CCTGGTCGAGGACCGCACCCAGAAGCCGACCTTCTACAAGGACTTCCCGACGTCCGTATCCCCCCTGACGCGCCCGCACC GCAGCATTGCCGGCGTCGCCGAGCGGTGGGACCTCGTCGCCTGGGGTGTCGAATTGGGCACCGCCTACAGCGAACTCACC GATCCGGTGGAGCAGCGTCGTCGACTGCAGGCGCAGTCGCTGCTCGCCGCGGGCGGTGATCCCGAGGCGATGGAACTCGA CGAGGACTTCCTCCAGGCCATGGAGTACGCGATGCCGCCCACCGGTGGGCTGGGCATGGGTGTCGATCGGGTGGTCATGC TGATCACCGGCCGCAGCATCCGGGAGACGCTCCCGTTCCCGTTGGCCAGACCACGTTGA Protein sequence : MTLTSPPRTRADSRYSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVDDYIFNFPDTSFAWAFVLALLAGALAA RKRIAWWILLLYMVAAAGWNVADLLTGDESVVDEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAV GVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTG EDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAP GVMGASVGGAEAFRAAGLSAIQLGDEAILLPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADA WRDTETERGFSMALGRLGDPADSDCLLVEAVQGGNGGQERSDPGDGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIEL MVSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDA RLIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKL KALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAA IDLGDLIAATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIR DTLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEF TLLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHEAVSEALGEHIDAATELPTL RKLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTQKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELT DPVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 4e-151 | 45 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-150 | 45 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 4e-151 | 45 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 4e-151 | 45 |
