Gene Information

Name : nrdF (Mmcs_1828)
Accession : YP_638993.1
Strain : Mycobacterium sp. MCS
Genome accession: NC_008146
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1970128 - 1971090 bp
Length : 963 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAGCTGATTGACCGCGTCTCGGCGATCAACTGGAACCGTCTGCAGGACGACAAGGACGCCGAGGTGTGGGACCGGCT
CACGGGCAACTTCTGGCTGCCCGAGAAGGTGCCGGTGTCCAATGACATCCCGTCCTGGAACACGCTGACCGCCCACGAGA
AGCAGCTCACGATGCGGGTGTTCACCGGTCTGACGCTGCTGGACACCATCCAGGGCACCGTCGGCGCGGTCAGCCTCATC
CCCGACGCGCTCACCCCGCACGAGGAGGCGGTGTACACCAACATCGCGTTCATGGAGTCGGTGCACGCCCGCAGCTACAG
CAACATCTTCTCCACGCTGTGCTCGACGGCCGAGATCGACGATGCGTTCCGCTGGTCGGAGGAGAACCCGAACCTGCAGC
GCAAGGCCGAGATCGTCATGCAGTACTACAAGGGTGACGAACCGCTCAAGCGCAAGGTCGCCTCGACGCTGCTGGAGAGC
TTCCTGTTCTACTCGGGTTTCTACCTGCCGATGTACTGGAGCAGCCGCGCCAAGCTGACCAACACCGCCGACATGATCCG
GCTGATCATCCGCGACGAGGCCGTGCACGGCTACTACATCGGCTACAAGTTCCAGAAGGGACTGGCGCTGCAGGATCCCG
CGACCCAGGCCGAGCTCAAGGACTACACCTACGAGCTGCTCTTCGAGCTGTACGACAACGAGGTCGAATACACCCAGGAC
CTCTACGACAGCGTCGGCCTGACCGAGGACGTCAAGAAGTTCCTGCGCTACAACGCCAACAAGGCCTTGATGAACCTCGG
GTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTCAACCCGGCGATCCTGTCCGCACTGAGCCCCAACGCCGACGAGA
ATCACGACTTCTTCTCCGGTTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTGGTCACCGAGGACGAGGACTGGGACTTC
TAG

Protein sequence :
MKLIDRVSAINWNRLQDDKDAEVWDRLTGNFWLPEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTAEIDDAFRWSEENPNLQRKAEIVMQYYKGDEPLKRKVASTLLES
FLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQKGLALQDPATQAELKDYTYELLFELYDNEVEYTQD
LYDSVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDEDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-113 75