Gene Information

Name : YPA_CD0028 (YPA_CD0028)
Accession : YP_636820.1
Strain :
Genome accession: NC_008122
Putative virulence/resistance : Virulence
Product : membrane-bound Yop protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 21958 - 24072 bp
Length : 2115 bp
Strand : +
Note : -

DNA sequence :
ATGAATCCCCATGATCTTGAGTGGCTAAATCGTATTGGCGAGCGTAAAGATATCATGCTGGCAGTGCTGCTGTTAGCTGT
GGTATTCATGATGGTCTTACCACTCCCCCCCCTTGTGTTGGACATTCTGATTGCTGTTAACATGACCATTTCAGTGGTGT
TGTTAATGATAGCGATCTATATCAACTCTCCTTTACAATTTTCAGCTTTCCCTGCGGTGCTACTCGTTACCACGTTATTT
CGTCTCGCACTTTCAGTTAGCACCACCCGCATGATCCTGCTACAAGCTGATGCGGGGCAGATTGTTTACACCTTTGGTAA
TTTCGTCGTTGGCGGTAACCTCATCGTCGGGATTGTCATCTTCCTGATCATCACTATTGTGCAATTTTTAGTGATAACGA
AAGGCTCAGAACGTGTAGCAGAAGTTAGTGCCAGATTCTCTCTTGATGCGATGCCGGGTAAACAGATGAGTATCGATGGC
GATATGCGAGCCGGGGTGATCGATGTCAATGAAGCGCGTGAGCGACGCGCGACGATAGAAAAAGAAAGCCAAATGTTCGG
TTCTATGGACGGCGCCATGAAGTTCGTCAAAGGGGATGCAATAGCCGGCCTCATTATTATCTTTGTCAATATATTAGGCG
GCGTCACCATTGGTGTTACCCAAAAAGGATTAGCGGCCGCTGAGGCACTGCAACTCTATTCCATCCTCACTGTCGGGGAT
GGGATGGTTTCTCAGGTACCTGCCCTGCTGATAGCTATTACCGCGGGTATTATCGTCACCCGCGTCTCTTCAGAAGATTC
ATCAGATCTGGGTAGCGATATTGGCAAACAGGTTGTCGCTCAGCCTAAAGCCATGCTAATTGGTGGCGTACTGCTGTTGC
TCTTTGGTCTTATCCCCGGCTTCCCAACAGTCACCTTTCTGATTTTGGCGCTATTGGTAGGCTGTGGTGGTTATATGCTC
AGCCGTAAGCAGAGTCGTAATGACGAGGCTAATCAAGACCTGCAATCCATACTGACGAGCGGTTCTGGCGCCCCGGCTGC
TCGAACCAAAGCCAAAACAAGTGGGGCAAACAAGGGCCGACTAGGGGAACAAGAAGCATTTGCTATGACGGTTCCCTTGC
TGATTGATGTAGATTCAAGCCAACAGGAAGCACTGGAAGCGATAGCACTAAATGATGAGCTGGTTCGAGTGCGCCGTGCT
CTTTATCTTGATCTTGGCGTACCTTTCCCTGGGATCCATCTGCGTTTTAATGAGGGGATGGGTGAAGGCGAATATATTAT
TTCCTTGCAAGAAGTTCCAGTGGCGCGAGGTGAGCTTAAGGCAGGTTATTTACTCGTGCGTGAATCCGTCAGCCAACTCG
AATTACTGGGTATACCCTATGAAAAAGGGGAACATTTGCTACCCGATCAGGAAGCTTTCTGGGTATCGGTTGAATATGAG
GAGCGCCTGGAAAAGTCTCAACTGGAATTTTTCTCTCATTCCCAAGTTCTAACCTGGCATCTTTCTCATGTCCTACGTGA
ATATGCCGAAGATTTCATTGGTATCCAAGAAACCCGCTATCTGCTCGAACAGATGGAAGGAGGCTATGGCGAATTAATTA
AAGAAGTACAAAGAATCGTTCCCTTACAACGAATGACCGAAATATTACAACGATTAGTTGGAGAAGATATTTCTATCCGT
AATATGCGATCTATTCTTGAAGCTATGGTGGAATGGGGACAAAAAGAGAAAGACGTCGTTCAACTCACAGAATATATCCG
CAGTAGTCTAAAACGTTATATCTGCTACAAATACGCTAATGGCAACAATATATTGCCGGCTTATCTTTTCGATCAAGAAG
TAGAAGAAAAAATTCGTAGCGGTGTGCGCCAAACCAGTGCAGGGAGTTATTTGGCATTGGAGCCTGCTGTTACCGAGAGT
TTACTTGAACAAGTTCGCAAGACTATTGGCGATCTATCGCAAATCCAGAGTAAACCGGTGCTGATTGTTTCTATGGATAT
TCGTCGCTATGTGCGCAAACTGATTGAGAGCGAATACTATGGCTTGCCGGTACTTTCATACCAAGAGCTGACTCAGCAGA
TTAATATCCAACCACTTGGACGAATTTGCTTATGA

Protein sequence :
MNPHDLEWLNRIGERKDIMLAVLLLAVVFMMVLPLPPLVLDILIAVNMTISVVLLMIAIYINSPLQFSAFPAVLLVTTLF
RLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLIVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDG
DMRAGVIDVNEARERRATIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGLAAAEALQLYSILTVGD
GMVSQVPALLIAITAGIIVTRVSSEDSSDLGSDIGKQVVAQPKAMLIGGVLLLLFGLIPGFPTVTFLILALLVGCGGYML
SRKQSRNDEANQDLQSILTSGSGAPAARTKAKTSGANKGRLGEQEAFAMTVPLLIDVDSSQQEALEAIALNDELVRVRRA
LYLDLGVPFPGIHLRFNEGMGEGEYIISLQEVPVARGELKAGYLLVRESVSQLELLGIPYEKGEHLLPDQEAFWVSVEYE
ERLEKSQLEFFSHSQVLTWHLSHVLREYAEDFIGIQETRYLLEQMEGGYGELIKEVQRIVPLQRMTEILQRLVGEDISIR
NMRSILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLFDQEVEEKIRSGVRQTSAGSYLALEPAVTES
LLEQVRKTIGDLSQIQSKPVLIVSMDIRRYVRKLIESEYYGLPVLSYQELTQQINIQPLGRICL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 0.0 82
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 2e-104 44
hrcV AAT96256.1 HrcV Virulence S-PAI Protein 4e-100 44
hrcV AAT96297.1 HrcV Virulence S-PAI Protein 2e-100 44
hrcV AAT96337.1 HrcV Virulence S-PAI Protein 8e-101 44
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 7e-100 43
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 6e-100 43
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-103 43
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 2e-97 43
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 2e-98 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 2e-98 42
escV AAC31514.1 L0035 Virulence LEE Protein 2e-98 42
escV ACU09459.1 EscV protein Virulence LEE Protein 2e-98 42
escV AAC38382.1 EscV Virulence LEE Protein 5e-99 42
escV NP_290269.1 hypothetical protein Virulence LEE Protein 2e-98 42
unnamed AAL06368.1 EscV Virulence LEE Protein 1e-97 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 6e-99 42
escV YP_003223476.1 translocator EscV Virulence LEE Protein 6e-99 42
escV CAC81861.1 EscV protein Virulence LEE II Protein 7e-99 42
escV AAK26714.1 EscV Virulence LEE Protein 5e-99 42
escV AAL57541.1 EscV Virulence LEE Protein 5e-99 42
escV CAI43875.1 EscV protein Virulence LEE Protein 5e-99 42
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 5e-105 42
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 5e-105 42
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 5e-105 42
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 5e-105 42
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 6e-80 41
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 6e-80 41
invA AAS66860.1 InvA Not tested SSR-2 Protein 7e-97 41
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-96 41
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 5e-93 41
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 7e-95 41
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 5e-95 41
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 1e-100 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0384 Protein 0.0 100
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0198 Protein 0.0 80
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0064 Protein 2e-178 59
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG2126 Protein 4e-129 46
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG2461 Protein 8e-98 43
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0813 Protein 1e-98 42
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0729 Protein 3e-99 42
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG0557 Protein 2e-105 42
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG1006 Protein 3e-98 41
YPA_CD0028 YP_636820.1 membrane-bound Yop protein VFG1780 Protein 1e-94 41