Gene Information

Name : pyk (MXAN_6299)
Accession : YP_634424.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 7774932 - 7776365 bp
Length : 1434 bp
Strand : -
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGCGAAGAGCGAAGATTGTCTGCACCCTCGGTCCCGCCAGCCAGAGCCAGGAGATGCTCGAAGCGCTCCTGGAGAACGG
CATGGACGTGGCTCGCCTGAACTTCTCCCACGGCAGCCACGAGCAGCACGCGGAGAACATCGCGAAGCTGCGCGCCGCGT
CGCTGAAGGTTCGCAAGGCGGTGGGCATCCTCGGCGACCTGCAAGGCCCGAAGATTCGCACTGGCCGTTTCGTGAAGGGC
AGCACCGAGCTGAAGGAAGGCGGCACCTTCCACATCACCACGGATGAAACGGTCCCGGGCACGGACGAAATCGTGTCCAC
GACGTACCCGTTCCTGGCCGCGGACGTGAATCCGGGGGACCGCATCCTCCTGGATGACGGCCTGCTGGAGCTGAAGGTCC
TGGAGACGGACAAGCAGAAGCTCATCCGCACGCAGGTCATCCACGGCGGCACGCTGAAGAACAACAAGGGCATCAACCTG
CCCGGCGTGGCGGTGCGCGCGGAGGCGCTGACGCCGAAGGACCGTGAGGACCTGGTGTTCGGGATCAAGGCCGGCGTGGA
TTACATCGCGCTGTCCTTCGTGCGCCAGCCGTCCGACCTGGACACCGCGCGCCAGGCCATGGCCGAGGTGGGCCGCACGG
TGCCCATCATCGCCAAGCTGGAGAAGCCGGAGGCCATTGCCCGGCTGGACGCCATCCTGGACAAGACGGACGGCGTGATG
GTGGCGCGCGGCGACCTGGGCGTGGAGATTCCCCCCGAGGAAGTGCCGGCCGTCCAGAAGGACATCATCCGGCGCTCCAA
CCTGCGCGGCCTGCCCGTCATCGTGGCCACGCAGATGCTGAACTCCATGATTGATAACCCGCGCCCCACGCGCGCCGAGG
CCAGCGACGTGGCCAACGCCGTGTTCGACGGCGCGGACGCGGTGATGCTGTCGGGCGAGACGGCCAGCGGCAAGTTCCCC
ATCGAGTCCGTGCAGATGATGGAGCGCATCATCCTGGCGGCCGAGTCCTCCGCGCGCACGACGCAGTCGCTGATGCGCGT
GCTGGAGACGCCGGTGGGGCTGCCCAACCACTTCCCGGACGTCATCGCGCGCGTGGCCTGCGAGGCGGCCAAGGCGAGCA
ACGCCTCGCTCATCGCGGCCTTCACGCTGTCGGGTGTGACGGCGCGCCTGCTGTCGCACTACCGGCCCCCGGTGCCGATT
GTCGCCTTCAGCCCCAACCAGGAAGTGCGCCGCCGGCTGTCGCTGTTGTGGGGCGTGGTGCCGCGCGTGCTGGAGCCCAC
CCAGGACACCGAGGCCATGGTGAAGCGCGTGGAGGAAGAGCTCCTGGCGCGAGGCCTGGGCCGCAAGGGCGACCGCATCG
TCATCGTGTTCGGCGCGCCCGTGGGGCAGCCGGGCAAGATCAACAGCCTGCGCCTGCACACCATCCAGGGCTGA

Protein sequence :
MRRAKIVCTLGPASQSQEMLEALLENGMDVARLNFSHGSHEQHAENIAKLRAASLKVRKAVGILGDLQGPKIRTGRFVKG
STELKEGGTFHITTDETVPGTDEIVSTTYPFLAADVNPGDRILLDDGLLELKVLETDKQKLIRTQVIHGGTLKNNKGINL
PGVAVRAEALTPKDREDLVFGIKAGVDYIALSFVRQPSDLDTARQAMAEVGRTVPIIAKLEKPEAIARLDAILDKTDGVM
VARGDLGVEIPPEEVPAVQKDIIRRSNLRGLPVIVATQMLNSMIDNPRPTRAEASDVANAVFDGADAVMLSGETASGKFP
IESVQMMERIILAAESSARTTQSLMRVLETPVGLPNHFPDVIARVACEAAKASNASLIAAFTLSGVTARLLSHYRPPVPI
VAFSPNQEVRRRLSLLWGVVPRVLEPTQDTEAMVKRVEEELLARGLGRKGDRIVIVFGAPVGQPGKINSLRLHTIQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-77 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-77 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-77 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-77 43
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-58 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_634424.1 pyruvate kinase VFG0479 Protein 1e-77 43