Gene Information

Name : thiC (MXAN_4235)
Accession : YP_632410.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 5194388 - 5196262 bp
Length : 1875 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCGGAGCGTCCAGAAGCCTGAAGGTCGACGGGAAGGTGCTGGAGGGAATCAGCCGGGGCCCGCTGCCAGCCTCGCG
CAAGGTGTACGTGCCCGGCGTGCTGCACCCGGACCTGCGCGTGCCCCTGCGCGAAATCAGCCAGACGCCCACGCGCCTCG
GCCACGGCCCGGACGCGAAGGAGACGGCCAACCCGCCGGTGCACGTCTACGACTCCAGCGGGCCGTATACGGATCCGGCC
GCGGAGCTCGACCTGCGGCAGGGGCTGCCCGCGCTGCGCGAGTCCTGGATCCTGGGCCGCAATGACACCGAAGCGCTGTC
CGGCGTGAGCTCCGAATACGGCCGCGCCCGTGAAGCGGACCCGCGTCTGGCGGGCCTGCGCTTCGCCCACCGCCGCTCGC
CGCGCGTGGCGAAGTCCGGCGCCAACGTCACGCAGTTGCACTACGCGCGCAAGGGCATCATCACCCCGGAGATGGAGTAC
GTGGCGCTGCGGGAGAATCTCCAGGTGGAGGCGTCGCTCGCGGCCCAGCACCCGGGCCAGTCGTGGGGCGCGGCGATTCC
GCGGGTGATTACGCCCGAGTTCGTGCGCGACGAAATCGCGCGGGGCCGCGCCATCATCCCGGCCAACATCAACCACCCGG
AGCTGGAGCCGATGATCATCGGCCGCAACTTCCTGGTGAAGATCAACGCCAACATCGGCAACTCGGCCGTCACGTCTTCC
ATCGAGGAAGAGGTGGAGAAGATGGTGTGGTCCATCCGCTGGGGCGCGGACACGGTGATGGACCTGTCCACCGGCCGAAA
CATCCACGAGACGCGCGAGTGGATCCTCCGCAACGCGCCGGTGCCCATCGGCACCGTGCCCATCTACCAGGCGCTGGAGA
AGGTGGGCGGCAAGGCGGAGGACCTCACCTGGGAGCTGTACCGCGACACGCTCATCGAGCAGTGCGAGCAGGGCGTGGAT
TACTTCACCATCCACGCGGGCGTGCTGCTGCGCTACGTGCCGTGGACGGCGAAGCGCCTGACCGGCATCGTCAGCCGTGG
CGGCTCCATCATGGCCAAGTGGTGCCTCGCCCACCACCGGGAGAACTTCCTCTACACGCACTTCGAGGAAATCTGCGAAA
TCATGAAGGCGTACGACGTCAGCTTCAGCCTGGGAGACGGGCTGCGGCCGGGCTCCATCGCGGATGCCAACGACGCGGCG
CAGTTCGGTGAGCTGGAGACGCTGGGCGAGCTCACCCAGATTGCCTGGAAGCACGACGTGCAGGTGATGATTGAAGGCCC
GGGCCACGTGCCCATGCACCTCATCCAGGAGAACATGACGAAGCAGCTGGCCGTGTGCGGCGAGGCGCCGTTCTACACGC
TGGGGCCTCTCACCACGGACATCGCGCCGGGCTACGACCACTTCACCAGCGGCATCGGCGCGGCGATGATCGGCTGGTTC
GGCACGGCGATGCTCTGCTACGTGACGCCCAAGGAGCACCTGGGCCTGCCGGATCGGGACGACGTGAAGGAAGGCGTCAT
CACGTACAAGATTGCCGCCCACGCCGCGGACCTGGCCAAGGGGCATCCAGGGGCCCAGGCCCGGGACAACGCGCTGTCCA
AGGCCCGCTTCGAGTTCCGTTGGGAGGACCAGTTCAACCTGTCGCTGGACCCCGAGCGCGCCCGCGCCTTCCACGACGAG
ACGCTTCCGGCGGAAGGCGCGAAGGTGGCGCACTTCTGCTCCATGTGCGGTCCGCAGTTCTGCTCCATGAAGATCACGCA
AGAGGTGCGTGACTTCGCGGCGAAGCAGGGCGTGAGCGACGACACCGCGCTTCAGTCCGCGCTCGATGAGAAGAGCGCGG
AATTCAAGAAGGCTGGGAGCCAGTTGTACCGCTAG

Protein sequence :
MSGASRSLKVDGKVLEGISRGPLPASRKVYVPGVLHPDLRVPLREISQTPTRLGHGPDAKETANPPVHVYDSSGPYTDPA
AELDLRQGLPALRESWILGRNDTEALSGVSSEYGRAREADPRLAGLRFAHRRSPRVAKSGANVTQLHYARKGIITPEMEY
VALRENLQVEASLAAQHPGQSWGAAIPRVITPEFVRDEIARGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSS
IEEEVEKMVWSIRWGADTVMDLSTGRNIHETREWILRNAPVPIGTVPIYQALEKVGGKAEDLTWELYRDTLIEQCEQGVD
YFTIHAGVLLRYVPWTAKRLTGIVSRGGSIMAKWCLAHHRENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAA
QFGELETLGELTQIAWKHDVQVMIEGPGHVPMHLIQENMTKQLAVCGEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWF
GTAMLCYVTPKEHLGLPDRDDVKEGVITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWEDQFNLSLDPERARAFHDE
TLPAEGAKVAHFCSMCGPQFCSMKITQEVRDFAAKQGVSDDTALQSALDEKSAEFKKAGSQLYR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 73
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 73