Gene Information

Name : guaA (MXAN_3775)
Accession : YP_631957.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4494778 - 4496331 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGACCTGCACGCCGAAAAAATCCTGATCCTCGATTTCGGGAGCCAGTACACCCAGCTCATCGCCCGGCGCGTCCGCGA
GCTGGGCGTCTATTGCGAAATCCACCGCCCGGACCTCCCGGCGGAGGACATCCGCAAGTACGCTCCCCGCGGCATCATCC
TCTCTGGCGGACCGGCGTCCGTGGAGGCCCCGGACTCCCCCCGGTGCGACCCGTTCGTCTTCGAAGCCGGCGTCCCCGTG
CTGGGCATCTGCTACGGCCTCCAGCTCACCGCCAAGCTGCTGGGCGGCAAGATTGACCGGAGCGCCCACCGCGAGTTCGG
CAACGCGGAGGTGGAGGTGCTGGCCCGCCGCGGCCCCTTCGCCGAATTCACCCCCGGGGACAGGGTCCAGGTCTGGATGA
GCCACGGCGACCGGGTGGAGGCGCTGCCCCCCGGCTTCGAGGCCATTGGCCGCAGCGGCAATTCGCCCTTCGCCGCCACC
GCCCACGCGACGAAGCCCTGGTTCGGCGTCCAGTTCCACCCGGAGGTGGTCCACACGCCGCAGGGCAAGGCCATGCTGCG
CGCCTTCGTCTTCAACGAGTGCAAGGTCAGCGGCTCGTGGACGATGAAGGGCTTCATCGACGAGGCCGTGGGCACCATCC
GCCGCCAGGTGGGTGAGCACGGCCGGGTCATCTGCGCGCTGTCGGGCGGCGTGGACAGCTCCGTGGCCGCGCTGCTGCTG
CACCGGGCCATTGGCCCCCGGCTCCAGTGCATCTTCGTGGACAACGGGGTGCTGCGGCAGAACGAGCGCGCCCAGGTGGA
GGCGCTCTTCGTGGACCGCTTCCACGTCCCGCTGAAGACGGTGGATGCCCGCCAGCGCTTCCTGGACAAGCTGGCCGGAG
TGACGGACCCGGAGAAGAAGCGGAAGATCATCGGCCGCGAGTTCATCGCCGTGTTCGAGGAGGCCGCGCGCGACGTGCAG
GACGCGGAGTTCCTGGCCCAGGGCACGCTGTACCCGGACGTCATCGAGTCCGTGTCGTACAAGGGCCCCTCCGTCACCAT
CAAGAGCCACCACAACGTGGGCGGCCTGCCGGAGACGATGAAGCTCAAGCTGGTGGAGCCACTGCGCGAGCTCTTCAAGG
ACGAGGTCCGCGCCCTGGGCCGCGAGCTGGGGCTGCCGGATGAGATGGTGTCCCGCCAGCCGTTCCCCGGCCCGGGTCTG
GCCATCCGCGTCCTGGGCGAAGTCACCGAGCAGCGCCTGGAGCTGGTGCGGCGCGCGGATGCCATCGTCCAGGAGGAGAT
TCGCAGCGCCGGCCTCTACAAGGAGGTCTGGCAGGCCTTCGCGGTGCTGCTGCCGGTGCAGAGCGTGGGCGTCATGGGCG
ACGAGCGCACCTACGAGTCCACCTGCGTGCTGCGCGCCGTCACCAGCGTGGACGGCATGACGGCGGACTGGGCCCGGCTG
CCGTTCCCCGTGCTGGAGCGCATCTCCACGCGCATCACGAACGAGGTGCGCGGCATCAACCGCGTCGCCTACGACATCTC
GTCCAAGCCCCCCGCGACCATCGAATGGGAGTAG

Protein sequence :
MDLHAEKILILDFGSQYTQLIARRVRELGVYCEIHRPDLPAEDIRKYAPRGIILSGGPASVEAPDSPRCDPFVFEAGVPV
LGICYGLQLTAKLLGGKIDRSAHREFGNAEVEVLARRGPFAEFTPGDRVQVWMSHGDRVEALPPGFEAIGRSGNSPFAAT
AHATKPWFGVQFHPEVVHTPQGKAMLRAFVFNECKVSGSWTMKGFIDEAVGTIRRQVGEHGRVICALSGGVDSSVAALLL
HRAIGPRLQCIFVDNGVLRQNERAQVEALFVDRFHVPLKTVDARQRFLDKLAGVTDPEKKRKIIGREFIAVFEEAARDVQ
DAEFLAQGTLYPDVIESVSYKGPSVTIKSHHNVGGLPETMKLKLVEPLRELFKDEVRALGRELGLPDEMVSRQPFPGPGL
AIRVLGEVTEQRLELVRRADAIVQEEIRSAGLYKEVWQAFAVLLPVQSVGVMGDERTYESTCVLRAVTSVDGMTADWARL
PFPVLERISTRITNEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-142 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-142 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-143 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-128 53