Gene Information

Name : MXAN_3645 (MXAN_3645)
Accession : YP_631832.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 4347103 - 4348749 bp
Length : 1647 bp
Strand : -
Note : identified by similarity to SP:P40871; match to protein family HMM PF00501; match to protein family HMM TIGR02275

DNA sequence : 
ATGACGTCCCCCGCCCTCCCTGGCTGCCCCACCTGGCCGGAGGCCTACGCCGCCCGCTACCGCGAGGCTGGCTACTGGCG
CAGTGAAACGTTCGGCCAGCTCCTCCACGAACGCGCCCAGCGTCACGGCGAGCGGACCGCACTGGTGGCCGGAGAGCGTC
GCCTCACCTACGCCAACCTGGACGCCCGCGTCAGCCAGCTGGCCGCCGGCTTCCATGCCCTGGGCATCCAGGCTCGGGAC
CGGGTGGTGGTGCAGCTGCCCAACGTGGCCGAGTTCTTCGAGGTCATCTTCGCCCTCTTCCGACTGGGCGCGCTGCCGGT
GTTCGCGCTTCCCGCGCACCGCGCTTCGGAGATTGGCTACTTCTGCGCCTTCACGGAGGCGGTGGCCTACGTCATCGCGG
ACAAGCAGGCCGGCTTCGACTACCGCACCCTGGCTGAGCAGGTGCGCGGCACCTGCCCGACGCTGAAACACGTCATCGTC
GCCGGTGACGCAGGCCCCTTCACGGCACTGAGCAGCCTGTACGCCGCGCCCACGGCGCTGCCGCCAGGGCCCGCGCCCAG
CGACGTGGCCTTCTTCCAGCTCTCCGGCGGAAGCACGGGCGTGCCCAAGCTCATCCCGCGCACGCACGACGACTACATCT
ACAGCCTGCGCGGCAGCGTGGACATCTGCCAGCTCGACGAGACGAGCGTGTACCTGTGCGCGCTGCCCGCGGCGCACAAC
TTTCCGCTCAGCTCGCCGGGCGTGCTGGGCACCTTCTACGCGGGCGGCACGGCGGTGCTGGCGCCCAACTCCAGCCCGGA
CACGGTGTTCCCGATCATCGAGCGTGAGCGCGTCACCATCACCGCGGTGGTGCCACCACTGGCCATGGTCTGGATGGACG
CGGCCAAGACGCGCCGGCACCAGCTCGCCAGCCTGCGGGTGCTCCAGGTCGGTGGCGCGCGCCTCAGCACCGAGGCGGCC
ATGCGGGTGAAGCCCACGCTGGGCTGCACGCTCCAGCAGGTGTTCGGCATGGCCGAGGGCCTGGTCAACTACACGCGCCT
GGATGACCCCGAGGACGTCATCGTCAGCACCCAGGGCCGGCCCATCTCCCCGGACGACGAAATCCGGGTGGTGGACGAGG
ACGGCGAAGACGTAGCGCCGGGCGAGACGGGCCAGTTGCTGACGCGCGGGCCGTACACCATCCGCGGCTACTACAAGGCG
GAGGCCCACAACGCGAAGGCCTTCACCGACGACGGCTTCTACCACACCGGTGACGTGGTCCGCGTGACGCCCCAGGGCTA
CCTGGTGGTGGAGGGCCGCGCCAAGGATCAGATCAACCGGGGCGGCGACAAGGTCGCGGCCGAGGAGGTGGAAAACCATC
TGCTGGCCCACCCCGACGTGCACGACGCCGCGGTGGTCGCCGTTCCGGACGCGTTCCTCGGCGAGCGCACCTGCGCCTTC
GTCATCGCGCGCGGCACGCCGCCAGCGCCCAATGTGCTCACGGCCTTCCTGCGCCAGCGTGGTCTGGCCGCCTTCAAGAT
TCCCGACCGGGTCGAGTTCGTCGAGGCGTTCCCCAAGACGGGCGTCGGCAAGGTCAGCAAGAAGGCGCTGCGCGACGTGC
TCGCCGGCGCTCCCTCCCCCACTCCGGTTTCGCGCGCGACGCGCTGA

Protein sequence : 
MTSPALPGCPTWPEAYAARYREAGYWRSETFGQLLHERAQRHGERTALVAGERRLTYANLDARVSQLAAGFHALGIQARD
RVVVQLPNVAEFFEVIFALFRLGALPVFALPAHRASEIGYFCAFTEAVAYVIADKQAGFDYRTLAEQVRGTCPTLKHVIV
AGDAGPFTALSSLYAAPTALPPGPAPSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVDICQLDETSVYLCALPAAHN
FPLSSPGVLGTFYAGGTAVLAPNSSPDTVFPIIERERVTITAVVPPLAMVWMDAAKTRRHQLASLRVLQVGGARLSTEAA
MRVKPTLGCTLQQVFGMAEGLVNYTRLDDPEDVIVSTQGRPISPDDEIRVVDEDGEDVAPGETGQLLTRGPYTIRGYYKA
EAHNAKAFTDDGFYHTGDVVRVTPQGYLVVEGRAKDQINRGGDKVAAEEVENHLLAHPDVHDAAVVAVPDAFLGERTCAF
VIARGTPPAPNVLTAFLRQRGLAAFKIPDRVEFVEAFPKTGVGKVSKKALRDVLAGAPSPTPVSRATR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-113 52
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-113 52
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-113 52
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-113 52
ybtE CAA21394.1 - Virulence HPI Protein 3e-113 52
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-113 52
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-112 51
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-112 51
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-113 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MXAN_3645 YP_631832.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-136 55
MXAN_3645 YP_631832.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 7e-111 47
MXAN_3645 YP_631832.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-111 47