Gene Information

Name : pyk (MXAN_3514)
Accession : YP_631708.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4094025 - 4095425 bp
Length : 1401 bp
Strand : -
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGCGCAAGGCGAAAATCATCTGCACCCTGGGCCCCGCTTCGGACACGCCCGAGGTCATCGAAGGGCTCATCCGCGCGGG
CATGAACATGGCGCGGTTGAACTTCTCGCACGGCACGCACGAGGAGCACCGCCGCCGAGTGGAAACCATCCGCAAGGTCG
CGAAGCGCCTGGGCACGCCGGTGGCCATCCTCCAGGACATCCAGGGGCCGAAGATCCGCCTGGGCCGCTTCGACGGGGGG
CAACTGCTGGTGAAGCAGGGCCAGTCCGTCACGGTGACGACGCGCAACGTCCTGGGCCAGGACGGCGTCATCCCCACCCC
CATCAAGTCGCTGGTGAAGGACGTGGCCAAGGGCCACGAAATCCTCCTGGACGACGGGCGCGTGCGGCTGCGGGTGCTGC
GCGTCCACGGGCAGGACGTGCAGTGCCGCGTGGAGGTGGGCGGCGTGCTCAAGAATCACAAGGGCCTCAACCTGCCCGGC
TCGCCCATGTCGGTGCCCACGATTACGCGCAAGGACGCGGTGGACCTGGCCTTTGGGCAGGAGGTGGGCGTGGACTACGT
GGCGCTGTCCTTCGTCCGCACGCCCGAGGACATCAAGAAGGCGCGCGCGCACGTGGCGAAGCTGAAGACGCCCCTCATCG
CGAAGATTGAAAAGCCCCAGGCGGTGGAGCGCGTGGAAGAGATTGCCGCCGTGGCGGACGGCATCATGGTGGCGCGTGGC
GACCTGGGCGTGGAGATGCCCCTGGAGCGCCTGCCGGCCATCCAGAAGCACATGGTGAGCGCGGTGAACCGCATGGGCGG
GCTCGTCATCGTCGCCACGGAGATGCTGGAGAGCATGGTGGCCAATGCGCGCCCCACCCGCGCCGAGGTGTCCGACGTGG
CCAACGCCATCCTCGACGGCGCGGACGCCGTCATGCTGTCGGGCGAGACGGCCGCGGGCAAGTACCCCGTCGAAGCGGCG
TCCACCATGGCGTGCATCGTGGAGGAGACGGAGCGCGGCGTGGTGAAGCACCAGCACCACTCCCCCTTCGAGCGCTCCGA
GGACCTGGGCACCGGCGTGGCCGCGGCGGCCGTGGCGGCGGCGACGCAACTGGGCATTGGCACCATCGTCGCCTACACGG
AGAGCGGCCACACCGCGCGCCTCATCTCCGAGTTCCGGCCCCACGCGCGCATCATCGCCCTCACGCCGAGCGAGACGGCC
GTGAATCGCATGGCGCTCTACTGGGGCGTGACGGGCATGCAGGTGGCGCGCGTGTCCACCACGGACGCCATGCTCACCCA
GGTGCGTCAGCTGTGCCGGAAGGAGAAGCTCTGCGCGCCCGGCACGCCCGTCGTGGTGGTGGCCGGTGTCCCGCTCAACG
TCCCGGGCAACACCAACCTGATGAGCATCCACCGCATCTGA

Protein sequence :
MRKAKIICTLGPASDTPEVIEGLIRAGMNMARLNFSHGTHEEHRRRVETIRKVAKRLGTPVAILQDIQGPKIRLGRFDGG
QLLVKQGQSVTVTTRNVLGQDGVIPTPIKSLVKDVAKGHEILLDDGRVRLRVLRVHGQDVQCRVEVGGVLKNHKGLNLPG
SPMSVPTITRKDAVDLAFGQEVGVDYVALSFVRTPEDIKKARAHVAKLKTPLIAKIEKPQAVERVEEIAAVADGIMVARG
DLGVEMPLERLPAIQKHMVSAVNRMGGLVIVATEMLESMVANARPTRAEVSDVANAILDGADAVMLSGETAAGKYPVEAA
STMACIVEETERGVVKHQHHSPFERSEDLGTGVAAAAVAAATQLGIGTIVAYTESGHTARLISEFRPHARIIALTPSETA
VNRMALYWGVTGMQVARVSTTDAMLTQVRQLCRKEKLCAPGTPVVVVAGVPLNVPGNTNLMSIHRI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-52 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-65 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-65 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-65 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_631708.1 pyruvate kinase VFG0479 Protein 4e-66 42