Gene Information

Name : MXAN_2566 (MXAN_2566)
Accession : YP_630785.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Resistance
Product : Bcr/CflA family protein drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 2985752 - 2986987 bp
Length : 1236 bp
Strand : -
Note : identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710

DNA sequence :
GTGCCTGACTTCAAATCCCCGTCGTGGAATCACGCTGTGCCAGCAGCGCTGTTGCTGATGGCGCCCTTCGACCTCCTGGC
CTCACTGGCCATGGACATCTACCTGCCAGTCGTTCCGGCGATGCCCGGAATCCTCAACACCTCTCCCGCCATCGTCCAGC
TCACCTTGAGCCTGTACATGGCGGTGCTTGGGCTCGGCCAGATGGTGTTTGGCCCGGTCTCCGACCGCATCGGCCGGCGC
CGAGTGCTGCTGACAGGCGCCCTCCTGTTCGCGGTCACGTCCTTCCTGCTCGCGGGGGCCTCGGATGCCGCGATGTTCGT
CGGCCTTCGGCTCGTCCAAGCCATGGGGGCATCCGCGGCCCTCGTCGCCACGTTCGCGACGGTCCGCGATGTCTACGCGG
AGCGCCCCGAGAGCGCGACCCTCTACAGCCTGTTCAGCGCCATGCTGGCCTTCGTCCCCGCGCTCGGGCCCATCGCGGGG
GCGCTGCTCATGCAGCGCTGGGGATGGCGAGCCATCTTCATCACACTCGGAGTCCTGGCCACGGCGGCGCTGCTCCAAGC
CTTGCCGCGGTGGCACGAGACGCGCCCGGCGCAGGGCCTTCAGTCACGTCCCGCGTTCCGGCACATCCTGCGCAGCGCCA
CGTTCTGGACGTACACCCTGGGCTTCAGCGCGGCCATGGGCTCCTTCTTCGTGTTCTTCTCCACGGCGCCCCGGGTGCTC
ATCGGTCAGGCCGGCTTCTCCGAGCTCGGGTTCAGCCTGGCGTTCGCTACCGCCGCGCTCGCGATGATTCTGACGACCCG
CTTCGCGAAGCGCTTCGTGGGGAGTTGGGGGCTGGCGGGTAGCCTCACGCGGGGCATGGGCATGTTGCTGCTCGGGGCGG
GGCTCCTGACGGCCGGACAGCTCCTGGCAACGCCGTCGTTCTGGACGTTCGTCGCGCCGATGTGGCTCATCGCGGCCGGC
ATCGTGTTCTCCGTCTCCGTCACCGCGAATGGCGCACTCCAGGCCTTTGGCGATGTGGCGGGAACGGCGGTCGCGCTCTA
CTTCTGCATCCAGAGCCTCATCGTCGGCGTCCTCGGCACGCTGATGGTCGTCCTGCTGGACGGCGACACGGCGTGGCCCC
TGGTGGGATACGCGTCCCTGATGGCAGGGGTGACGTTGACGGCGCTTCAGCGCCTCCAGCGCCGACAACGCGTCCTGACG
AAACCCGCGATGGCGGAAAGCCCCGACGCCCCCTAG

Protein sequence :
MPDFKSPSWNHAVPAALLLMAPFDLLASLAMDIYLPVVPAMPGILNTSPAIVQLTLSLYMAVLGLGQMVFGPVSDRIGRR
RVLLTGALLFAVTSFLLAGASDAAMFVGLRLVQAMGASAALVATFATVRDVYAERPESATLYSLFSAMLAFVPALGPIAG
ALLMQRWGWRAIFITLGVLATAALLQALPRWHETRPAQGLQSRPAFRHILRSATFWTYTLGFSAAMGSFFVFFSTAPRVL
IGQAGFSELGFSLAFATAALAMILTTRFAKRFVGSWGLAGSLTRGMGMLLLGAGLLTAGQLLATPSFWTFVAPMWLIAAG
IVFSVSVTANGALQAFGDVAGTAVALYFCIQSLIVGVLGTLMVVLLDGDTAWPLVGYASLMAGVTLTALQRLQRRQRVLT
KPAMAESPDAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 8e-98 67
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 8e-98 67
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 8e-98 67
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 8e-101 67
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 8e-101 67
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 3e-97 66
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 5e-71 51
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 5e-71 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MXAN_2566 YP_630785.1 Bcr/CflA family protein drug resistance transporter DQ984668.gene.p01 Protein 3e-71 51
MXAN_2566 YP_630785.1 Bcr/CflA family protein drug resistance transporter AF156486.gene.p01 Protein 6e-70 51
MXAN_2566 YP_630785.1 Bcr/CflA family protein drug resistance transporter DQ522237.1.gene4.p01 Protein 3e-71 51
MXAN_2566 YP_630785.1 Bcr/CflA family protein drug resistance transporter NC_010410.6003586.p0 Protein 3e-71 51
MXAN_2566 YP_630785.1 Bcr/CflA family protein drug resistance transporter AF294653.1.gene4.p01 Protein 3e-71 51