Gene Information

Name : MXAN_2442 (MXAN_2442)
Accession : YP_630662.1
Strain : Myxococcus xanthus DK 1622
Genome accession: NC_008095
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 2849437 - 2850750 bp
Length : 1314 bp
Strand : +
Note : identified by similarity to SP:P23445; similarity to SP:P40290; match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546

DNA sequence :
ATGGCCATTGACCTCTCGCGGTACTTCGACCTCATCAAGGAAGCGCAGGTCGTGCGCGTGCGCGGCCGCGTCACGGAGCT
GACGGGCCTCATCATCAAGGCCAGCGTGCCCAACGTCCGCGTGGGCGAGCTGGTGCTCATCAAGAGCCGCAACCGCGGCG
CGGTGAAGGCGGAGGTGGTGGGCTTCCAGGGGGATGAGGTGATGCTCATGCCCCTGGGCGAGCTGCACGGCATCGGTCCG
GACAGCGAGGTCATCCCCACCGGCAAGCCGCTGAGCATCAAGTGCGGAGAGGCGCTGCTGGGCCGTGTGCTCAACGGAAT
CGGCGAGCCCATGGACGGCCACCCGTTGCCGGAGGAGGGCCTCATCGACTGGTCCGTGGACCGCGACTGCCCGGACCCCT
TCACCCGCCAGCGCATCGAGCGGCCACTTCCCCTGGGCGTGCGCTGCATCGATGGGCTGCTCACGGTGGGAGAGGGTCAG
CGCGTGGGCCTCTTCGCCGGCTCCGGCGTCGGCAAGTCCACGCTGATGGGGCAGATTGCCCGGAACACCAAAGCGGACCT
CTGTGTGGTGGCGCTCATCGGCGAGCGTGGCCGCGAAGTCCGTGAGTTCATCGAAGACGCCATGGGCGAGGAGGGCATGA
AGCGCTCCGTGCTGGTGTGCGCCACCTCCGACCAGCCCAGCCTCGTGCGTCTGCGCGCGGCCTATGTCGCCACCGCCATC
GCCGAGTACTTCCGCGAGCGCGGCGGCAACGTGCTCTTCATGCTGGATACGGTGACGCGTCTGGCACGTGCCCAGCGTGA
GATTGGCCTCGCCGTGGGTGAGCCCCCGGCCCGTCAAGGCTACCCGCCGAGCGTGTTCTCCATGCTGCCGCGCATCCTGG
AGCGCACGGGCAACTCGGAGAAGGGCAAGTGCACCGCCATCTACACCTGCCTCGTGGCCGGCGGTGACATGGAAGAGCCC
ATCGCCGACGAGGTCCGCGGTATTCTCGACGGCCACTTCATCCTCAACCGTGCCCTGGGTGAGCGCAACCAGTGGCCCGC
GATGGACGTGCTCGCCAGCCTCAGCCGTGTGATGAGCGGCATCGTCTCCAAGGACCACAAGAAGGCGGCGGGACGGCTCC
GAGAGCTGCTCTCCACGTATGAGAAGCAGCGCGACCTCATCCTCCTGGGGGCCTACCAGTACGGGACGGATCCCCGCACG
GATCAGGCCATCGACAAGTACGACGCCATCATCGACTTCCTCAAGCAGGACACCCACTCCAACTCCGGGTTCGAGGAGAC
GGTGGAGCAGCTGATCGCCCTGTTCGACGAGTAA

Protein sequence :
MAIDLSRYFDLIKEAQVVRVRGRVTELTGLIIKASVPNVRVGELVLIKSRNRGAVKAEVVGFQGDEVMLMPLGELHGIGP
DSEVIPTGKPLSIKCGEALLGRVLNGIGEPMDGHPLPEEGLIDWSVDRDCPDPFTRQRIERPLPLGVRCIDGLLTVGEGQ
RVGLFAGSGVGKSTLMGQIARNTKADLCVVALIGERGREVREFIEDAMGEEGMKRSVLVCATSDQPSLVRLRAAYVATAI
AEYFRERGGNVLFMLDTVTRLARAQREIGLAVGEPPARQGYPPSVFSMLPRILERTGNSEKGKCTAIYTCLVAGGDMEEP
IADEVRGILDGHFILNRALGERNQWPAMDVLASLSRVMSGIVSKDHKKAAGRLRELLSTYEKQRDLILLGAYQYGTDPRT
DQAIDKYDAIIDFLKQDTHSNSGFEETVEQLIALFDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 9e-107 55
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-103 55
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-103 55
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-102 55
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-103 55
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-103 55
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-102 55
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-104 55
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-102 54
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-102 54
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-87 50
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-84 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-79 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-80 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-81 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-80 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-81 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-81 48
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 9e-92 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-82 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-83 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-81 48
escN AAL57542.1 EscN Virulence LEE Protein 1e-84 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-84 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-84 48
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-85 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-85 48
escN AAC31513.1 L0034 Virulence LEE Protein 7e-85 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-85 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-85 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-85 48
escN AAC38383.1 EscN Virulence LEE Protein 3e-85 48
escN AAK26715.1 EscN Virulence LEE Protein 1e-84 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-81 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-84 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-75 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-85 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-85 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-77 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-85 46
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-77 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-80 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-80 46
invC AAS66861.1 InvC Not tested SSR-2 Protein 7e-70 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 8e-67 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-62 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-62 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-62 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-62 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 4e-62 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG2144 Protein 2e-113 56
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0390 Protein 2e-107 55
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0192 Protein 2e-108 55
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0048 Protein 5e-107 54
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0515 Protein 3e-81 48
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG1254 Protein 9e-91 48
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0812 Protein 4e-85 48
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0730 Protein 2e-85 48
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG2331 Protein 1e-84 45
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG2499 Protein 7e-80 44
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG2459 Protein 1e-71 43
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG1008 Protein 3e-70 42
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG0555 Protein 2e-62 41
MXAN_2442 YP_630662.1 FliI/YscN family ATPase VFG1778 Protein 6e-67 41