Gene Information

Name : hemC (HPAG1_0240)
Accession : YP_626981.1
Strain : Helicobacter pylori HPAG1
Genome accession: NC_008086
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 244115 - 245035 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
GTGGGAAATTTAGTGATTGGCTCTAGGGGGAGCGAACTAGCCTTATGGCAAGCGAATCACATTAAAGAACGCCTGAAAAA
AGAATGCTTGATAGAAAGCGAGATTCAAATCGTTAAGACTAAGGGCGATAAAATCTTAGACACCCCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAGGAATTAGAAGAATTGCTTTTAAAAGGCGAAATTGATTTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACTAAAAGGGCTGATGTGAGGGACACTTTTTTAAG
CGTGAAATTCCCTGATTTGATGAGCTTGCCCAAAGGGGCAAAGGTTGGCACGACTTCTTTAAGGCGCTCTATGCAGATCA
AACTGAAACGCCAGGATTTAGACACAGAAAGCTTAAGGGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGAGAA
TTTGACGCTATCATTTTAGCTGAAGCCGGGTTGTGCCGCCTAGAAATTCAAGGAGCGAAATACCGCAAGGCTTTTAGCGT
AAAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAACCACAAGCATTTTATTACGCTTC
AAAAACTCAACGACGAGAAAAGCGCGTTTTGCTGCCGTTTAGAAAGGGAGTTTATCAAGGGGCTTAATGGGGGGTGTCAG
ATCCCTATTGGCGTGCATGCGAGTTTAATGGGCGATAGGGTTAAAATCCAGGCGGTTTTAGGCTTGCCTAACGGGAAAGA
AGTCATCGCTAAAGAAAAACAAGGGGATAAAACTAAAGCGTTTGATTTAGTTCAAGAGCTTTTAGAAGAATTTTTGCAAA
GCGGGGCTAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGEIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQIKLKRQDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLEIQGAKYRKAFSVKEMIPSMGQGALGVEMLKNHKHFITLQKLNDEKSAFCCRLEREFIKGLNGGCQ
IPIGVHASLMGDRVKIQAVLGLPNGKEVIAKEKQGDKTKAFDLVQELLEEFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-44 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-44 46