Gene Information

Name : HPAG1_1433 (HPAG1_1433)
Accession : YP_628174.1
Strain : Helicobacter pylori HPAG1
Genome accession: NC_008086
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1489235 - 1490482 bp
Length : 1248 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGACAGAAAACTTTTATTGCAAGATTTTGACAAGGTGGCTCTTTCTTTAAAAAAGCGTAATCATGCGATGGGTGA
TGAGTTGGAGCGTTTGCGCGAAGTCATCACGCATTATAAAAAGCAGCTCATTGAATTGGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGCATCAAAATGGCTCAAAAAGTGGATACAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAATTGAATGAGCTTTCCAAAAGCGTGGGCGAATTGGAGCAACAAATTGATTTGAAACTTTCCATAATCCCTAA
TCTGGTGGATGAAAAAACCCCTTTAGGTGCAAGCGAAGAAGATAATATAGAAATTAAAAAAATATTAACCCCAAGGGTCT
TCACTTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAATGGCTGGATTGATTTTGAAAGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCTGTCATCAGGGGTTTTGGGGCTAAAATTTATCGTGCGCTCATTCATTTAATGCTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGATGTTTTCAAAATAGAAAATGAAAATTTGTATTTAATCCCCACCGCTGAAGTAACGCTCACTAATCTCTAC
AACGACACGATCATTGGCGTTGAAAATCTCCCCATTAAAATGACCGCACACACGCCTTGTTTTAGGAGCGAAGCAGGGAG
TGCGGGCAAGGACACAAGGGGGATGATAAGACAGCACCAGTTTGATAAAGTGGAGCTAGTGGCTATCACGCACTCTAAAG
AAAGCGATGCCATGCAAGAGCATATGCTAGAGAGCGCGAGCGAAATTTTAAAGGCTTTGGAATTACCGCACCGGTTTGTG
CAATTGTGCAGCGCGGATTTAGGCTTTAGCGCGAGCAACACCATAGATATTGAAGTGTGGCTGCCCGGGCAAAATTGCTA
CCGAGAAATCAGCTCGGTGTCTAACACGAGGGATTTTCAGGCTAGGCGAGCCAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGCGCACACCTTAAACGGCTCTTCTTTAGCGGTAGGCAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GAAGATGGGAGCATCCACATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDRKLLLQDFDKVALSLKKRNHAMGDELERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENN
KIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGASEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIIGVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHSKESDAMQEHMLESASEILKALELPHRFV
QLCSADLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
EDGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-76 45