Gene Information

Name : leuS (Ldb1570)
Accession : YP_619369.1
Strain : Lactobacillus delbrueckii ATCC 11842
Genome accession: NC_008054
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1348308 - 1350722 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTACAACCATAAAGTTGTCGAAAAGAAGTGGCAAAAGTACTGGCTGGAAAACAAGACTTTTAAGACCGGGACTGACCC
GGAAAAGCCAAAGTACTACGTTCTTGACATGTTCCCTTACCCATCTGGCAAGGGCCTGCACGTTGGTCACCCGGAAGGTT
ACACCGCTACTGACATCATGGCCAGAATGAAGCGGGCCCAAGGCTACAATGTCTTGCACCCAATGGGTTGGGATGCCTTC
GGTCTGCCGGCAGAACAATACGCCCTGCAAACTGGTAACGACCCGGCAACTTTCACCGACGAAAACATTGCCCACTTCAA
GAAGCAGCTGCAAGCTTTGGGCTTCTCCTATGACTGGGACCGGGAAATCAAGACTACTGACCCGAACTACTACAAGTGGA
CCCAGTGGATTTTTGAACAAATGTACAAGATGGGCCTGGCCTATGAAGCTGAAGTACCGGTTAACTGGTCACCAGACCTG
GGCACGGTTGTCGCTAACGAAGAAGTTATCGACGGCAAGACTGAACGGGGCGGCTACCCGGTTTACCGGCGCAAGATGCG
GCAATGGATGCTGAAGATCACTGCTTATGCTGACCGTTTGCTGGACGACCTGGACGACTTGGACTGGCCAGAACCGATCA
AGGAAATGCAAAGAAACTGGATCGGCCGCTCAGTTGGGGCCCAGGTAACCTTCAAGATCAAGGACTCAGACAAGAGCTTT
GCCGTCTTCACTACCCGGCCGGACACCCTCTTTGGCTGCTCATACACGGTTTTGGCCCCGGAAAACGAACTGGTTAAGGA
AATCACCAGTCCAGAGCAAAAGGAAGCCGTTGACGCCTACATCAAGTCCATTGAATCCAAGTCTGACCTGGAAAGAACTG
ACTTGAACAAGGACAAGACCGGGGTCTTCACTGGTGCTTACGCTATCAACCCGGTTAACGGGGAAGAAGTGCCAGTCTGG
ATTTCTGACTACGTTTTGGCAACTTACGGGACCGGGGCAGTTATGGCCGTTCCAGCCCATGACGAAAGAGACTACGCTTT
TGCCACTAAGTTCGACCTGCCAATCAAGGAAGTCGTTGAAGGCGGCGACATCAGCAAGGAAGCCTTTGCCGGTGACGGGG
TCCACGTCAACTCAGACTTTTTGAACGGCCTGCACAATGAAGAAGCCAAGGCCAAGATGGTTGACTGGCTGACTGAAAAG
GGCGTCGGCGAAAAGAAGGTCAACTACAAGATGCGGGACTGGAACTTCTCCCGTCAGCGCTACTGGGGTGAACCAATCCC
GGTCATCCACTGGGAAGACGGGGAAACCACTTTGGTGCCAGAAGACGAACTGCCGCTGCGCCTGCCTAAGGAAAGCAACA
TCAAGCCGTCCGGCACTCCGGAAAGTCCGCTGGCCAACTTGACTGACTGGGTCAACGTTGTTGACGAAAACGGCCGGAAG
GGCAAGCGGGAAACCAACACCATGCCCCAATGGGCTGGTTCAAGCTGGTACTTCCTGCGCTACATTGACCCGCACAACGA
CAAGGCCCTGGCTGACCCGGAACTCTTGAAGAAGTGGATGCCAGTTGACCTTTACATCGGCGGGGCAGAACACGCGACCT
TGCACCTGCTTTACGCTAGATTCTGGCACAAGGTTCTTTACGACTTGGGCGTCGTTCCAACCAAGGAACCGTTCCAAAAG
CTCTACAACCAGGGCTTGATCTTGAAGAACCATGAAAAGATGTCCAAGTCCCGGGGCAACGTGGTTAACCCAGACGACGT
CGTTGACGAATACGGTGCCGACAGCCTGCGGACTTACGAAATGTTCATGGGGCCTTTGAACGCGTCTATTGACTGGGATG
ACAACGGTCCTTCCGGTGTTAAGAAGTTCCTTGACCGGGTATGGCGGACTTTTGTCAATGACTTAGACCTGGATCCGATC
CCATCTGAAAAGATCACTGACAAAAACGACGGCAAGCTGGACAAGATCTACAATGAAACGGTCAAGACTGTTACGGAACA
CTTTGAAGAACTGCGCTTCAACACGGCTATTTCCCAAATGATGGTCTTCATGAACGCCTGCCAAAAGGTCGACAAGATTC
CGCGGGAATACGCTGAAGGCTTCGTGAAGCTGATGGCTCCGGTTGCTCCGCACATGATGGAAGAAATCTGGCATGTCTTC
GGCCACGACGAAAGCGTGCAGTTTGCTGCCTGGCCAACTTACGACGCAAGCAAGCTGGTTGAAAGCACGGTTGAAATGGC
GGTTACGGTCAACGGCAAGAAGCGGGGCAACTTCCAAATAGCCAAGGACGCAAGCAGAGAAGAAGCCCAAGCTGCCGCAA
CCGCTCTGACGCACGTAAAGGAATTTTTGGAAGGCAAGGAGATCAAGAAGGTCATTGTCGTGCCAAACAAGATCGTGAAC
ATTGTTGCCAAATAA

Protein sequence :
MYNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMARMKRAQGYNVLHPMGWDAF
GLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDREIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDL
GTVVANEEVIDGKTERGGYPVYRRKMRQWMLKITAYADRLLDDLDDLDWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSF
AVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKTGVFTGAYAINPVNGEEVPVW
ISDYVLATYGTGAVMAVPAHDERDYAFATKFDLPIKEVVEGGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEK
GVGEKKVNYKMRDWNFSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRK
GKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYARFWHKVLYDLGVVPTKEPFQK
LYNQGLILKNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDRVWRTFVNDLDLDPI
PSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNACQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVF
GHDESVQFAAWPTYDASKLVESTVEMAVTVNGKKRGNFQIAKDASREEAQAAATALTHVKEFLEGKEIKKVIVVPNKIVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65