Gene Information

Name : guaA (Sala_0634)
Accession : YP_615688.1
Strain : Sphingopyxis alaskensis RB2256
Genome accession: NC_008048
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 643677 - 645290 bp
Length : 1614 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCGGCTTCCTTATCGGCCAGCCATGCCGACTCCCGACCCCTCCGCCGCCCCTGAATCGATCCTGATCATCGACTT
CGGATCGCAAGTCACCCAGCTCATCGCCCGTCGCGTCCGCGAGGCGGGCGTGTATAGCGAGATTGTCCCGTTCAGCGCCG
CCGAGGCGGCGCTCGCACGGATGCGGCCCAAGGGGGTGATCCTGTCAGGATCGCCCGCGTCGGTTCCCGCCGAGGGCAGC
CCGCGCGCACCCCGGTCGATCTTTGACAGCGGCCTGCCGATCCTGGGCATCTGTTACGGCCAGCAGGTGATGAGCCAGCA
GCTCGGCGGAAAAGTCGAACCCGGCGGCATCGATGGCGAACGCGACGGCGAATTCGGCCGCGCCTTCCTGACCGTCACCG
AACCCTGCGTGCTGTTCGATGGGCTGTGGCAGGTCGGCGAACGGCATCAGGTGTGGATGAGCCACGGCGACCGCGTGACC
CGGTTCGCGCCGGGTTTCCGTATCGTGGCAGTCAGCGACGGCGCGCCTTTCGCAGTCATCGCGAATGACGAGCGCCGCTA
TTATGGTACCCAATTCCACCCCGAAGTCGTCCATACCCCCGACGGCGCGAAGCTGATCGCCAATTTCGTGCGCCACGTCT
GCGGGTGCAGCGGCGACTGGACGATGGCCGAGTTTCGCACCACCAAGATCGCCGAAATCCGCGCACAGGTCGGCGACCAG
CGCGTGCTGTGCGGCCTGTCGGGCGGGGTCGACAGCGCGGTCGCCGCGGTGCTGATCCACGAAGCGATCGGCGAACAGCT
GACCTGCGTTTTCGTCGACCACGGCCTCTTGCGCATGAACGAGCGCGAACAGGTCGAACGCCTGTTCCGCGACCATTACA
ACATCCCGCTGGTCGTCGTCGACGCCGAGGAGCGCTTCATGGCGGGGCTTGCGGGCATCACCGACCCCGAACAGAAGCGC
AAGTTCATCGGCGCCGAGTTCATCAATGTGTTCGAGGAAGAGGCCAGGAAGATCGGCGGCGCCGATTTCCTCGCGCAAGG
CACGCTCTATCCCGATGTGATCGAGAGCGTCAGCTTCACCGGCGGGCCGAGCGTCACGATCAAGAGTCATCACAATGTCG
GCGGCCTGCCCGAACGCATGAACATGAAGCTCGTCGAGCCGCTGCGCGAGCTGTTCAAGGACGAGGTCCGCCTGCTCGGC
AAGGAGCTGGGCCTGCCCGACATTTTTGTCGGCCGCCACCCCTTCCCCGGCCCCGGCCTCGCGATCCGCATTCCAGGCGA
AGTCAGCAAAGAGCGCTGCGACATCCTCCGCAAGGCCGATGCGGTCTATCTCGAGGAAATCCGCAACGCCGGGCTGTACG
ATGCGATCTGGCAGGCGTTTGCGGTGCTCCTGCCGGTCAAGACGGTCGGCGTGATGGGCGACGGGCGCACTTACGACCAT
GTCTGCGCGCTGCGCGCCGTGACCTCGACCGATGGCATGACCGCCGACATCTATCCCTTCGACGCCAGCTTCCTGAGCCG
CTGCGCGACGCGCATCATCAACGAGGTGCAGGGCATCAACCGGGTGGTGTATGATTATACGTCGAAGCCGCCGGGGACGA
TCGAGTGGGAGTGA

Protein sequence :
MARLPYRPAMPTPDPSAAPESILIIDFGSQVTQLIARRVREAGVYSEIVPFSAAEAALARMRPKGVILSGSPASVPAEGS
PRAPRSIFDSGLPILGICYGQQVMSQQLGGKVEPGGIDGERDGEFGRAFLTVTEPCVLFDGLWQVGERHQVWMSHGDRVT
RFAPGFRIVAVSDGAPFAVIANDERRYYGTQFHPEVVHTPDGAKLIANFVRHVCGCSGDWTMAEFRTTKIAEIRAQVGDQ
RVLCGLSGGVDSAVAAVLIHEAIGEQLTCVFVDHGLLRMNEREQVERLFRDHYNIPLVVVDAEERFMAGLAGITDPEQKR
KFIGAEFINVFEEEARKIGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRLLG
KELGLPDIFVGRHPFPGPGLAIRIPGEVSKERCDILRKADAVYLEEIRNAGLYDAIWQAFAVLLPVKTVGVMGDGRTYDH
VCALRAVTSTDGMTADIYPFDASFLSRCATRIINEVQGINRVVYDYTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-133 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-118 52