Gene Information

Name : Sala_2370 (Sala_2370)
Accession : YP_617412.1
Strain : Sphingopyxis alaskensis RB2256
Genome accession: NC_008048
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2492752 - 2494644 bp
Length : 1893 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGCCGACATCGACAGCCGCCTCGACACGACGCAAGCCACCCCCATCGGCGTCACCACCGGGCCGATCCGCGGCAGCCG
CAAGATCCACGTCGCCAGCCCCACCGGCAGCGGCATCCGCGTCGCGATGCGCGAGATCCTGCTCGAACCCTCATCGGGCG
AACCGCCGGTGCGCGTCTACGACACCAGCGGGCCTTATACGGACCCCGATGCGACGATCGACATCGCCCAGGGCCTCCCC
GAACTGCGGGCAAGCTGGATCCGCGCCCGCGGCGACGTCGAAGAGGTGGCCCAGCGCGAGGTTCGGCCGGAGGACAACGG
CCAGCTCGGCCCCGACCGTTCGGGCGGCGTCCCCGCCTTCCCCAATGTCCGCAAGAAAGTGCTGCGCGCCAAGCCCGGCG
CGAACGTCAGCCAGATGCACTATGCCCGCCGCGGCATCATCACGCCCGAGATGGAATATGTCGCGACGCGCGAGAATCTC
GGCCGCGAACGGCTCGCCGAATATGTCCGCGACGGGCAGGACTGGGGCGCCAGCATCCCCGACTATGTCACCCCCGAATT
CGTCCGCGACGAGGTCGCGCGCGGCCGCGCGATCATCCCCAGCAACATCAACCACCCCGAAAGCGAGCCGATGGCGATCG
GCCGCAACTTCCTCGTCAAGATCAACGCCAATATCGGCAACAGCGCGGTCGCCAGCGACGTCGCGGCCGAGGTCGACAAG
ATGGTCTGGTCGATCCGCTGGGGCGCCGACACCGTCATGGACCTGTCGACCGGGCGCAACATCCACGACACGCGCGAATG
GATCCTCCGCAACTCGCCCGTCCCGATCGGCACCGTCCCCATCTATCAGGCGCTCGAAAAGGTCGGCGGCATCGCCGAGG
AACTGACGTGGGAAATCTTCCGCGACACGCTGATCGAACAGGCCGAACAGGGCGTCGACTATTTCACCATCCATGCGGGT
GTCCGTCTGCCTTACGTGCCCCTCGCCGCGAAGCGCGTCACCGGCATCGTCAGCCGCGGCGGCAGCATCATGGCGAAATG
GTGCCTCGCGCATCACAGGGAAAGCTTCCTCTACGACCATTTCGACGAGATTACCGAGATCATGAAGGCCTATGACATCG
CCTACAGCCTCGGCGACGGCCTGCGCCCCGGCAGCATCGCCGACGCGAATGACGAGGCGCAGTTTGCCGAGCTCTACACG
CTGGGCGAGCTTACCAGGCGCGCGTGGGCACAGGATGTGCAGGTGATGATCGAGGGACCGGGGCATGTTCCCATGCACAA
GATCAAGGAGAATATGGACAAGCAGCTCGAGGCCTGCGGCGAGGCGCCCTTCTACACCCTGGGGCCGCTCACCACCGACA
TCGCGCCCGGCTACGACCATATCACCAGCGGCATCGGCGCCGCGATGATCGGCTGGTACGGCACCGCGATGCTTTGCTAC
GTCACGCCCAAGGAGCATCTGGGCCTGCCCGACCGCGACGATGTGAAGGTCGGCGTCGTCACCTACAAGCTCGCCGCCCA
CGCCGCCGACCTCGCCAAGGGCCACCCCGCCGCGCAGGTCCGCGACGATGCGCTGTCAAAGGCGCGCTTCGAGTTCCGCT
GGCGCGACCAGTTCAACCTGTCGCTCGACCCCGACACCGCCGAGCAATATCACGACCAGACCCTCCCCGCCGAGGGCGCC
AAGACCGCGCATTTCTGCAGCATGTGCGGGCCGAAGTTCTGCTCGATGAAGATCAGCCAGGAGGTGCGCGAGTTCGCGAA
GCTGCAAAATCAGGACAGCGCCGGTTTCATCGCGGCAGAAGAGGCCGAAAAGGGCATGGCGGAAATGAGTCAGGTCTATG
AGGACACGGGGCGCGAGCTGTATATGGGCGCTGGTGGGCGCGAGCATGATTGA

Protein sequence :
MADIDSRLDTTQATPIGVTTGPIRGSRKIHVASPTGSGIRVAMREILLEPSSGEPPVRVYDTSGPYTDPDATIDIAQGLP
ELRASWIRARGDVEEVAQREVRPEDNGQLGPDRSGGVPAFPNVRKKVLRAKPGANVSQMHYARRGIITPEMEYVATRENL
GRERLAEYVRDGQDWGASIPDYVTPEFVRDEVARGRAIIPSNINHPESEPMAIGRNFLVKINANIGNSAVASDVAAEVDK
MVWSIRWGADTVMDLSTGRNIHDTREWILRNSPVPIGTVPIYQALEKVGGIAEELTWEIFRDTLIEQAEQGVDYFTIHAG
VRLPYVPLAAKRVTGIVSRGGSIMAKWCLAHHRESFLYDHFDEITEIMKAYDIAYSLGDGLRPGSIADANDEAQFAELYT
LGELTRRAWAQDVQVMIEGPGHVPMHKIKENMDKQLEACGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGTAMLCY
VTPKEHLGLPDRDDVKVGVVTYKLAAHAADLAKGHPAAQVRDDALSKARFEFRWRDQFNLSLDPDTAEQYHDQTLPAEGA
KTAHFCSMCGPKFCSMKISQEVREFAKLQNQDSAGFIAAEEAEKGMAEMSQVYEDTGRELYMGAGGREHD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 69
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 68