Gene Information

Name : thyA (TM1040_1729)
Accession : YP_613724.1
Strain : Ruegeria sp. TM1040
Genome accession: NC_008044
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1825228 - 1826061 bp
Length : 834 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCAGCAGTATCATGACGCTTTGCAGCATATTCTTGATCACGGGGTCGAGACGACGGATCGTACCGGCACCGGCACTCT
GTCGTGTTTTGGAATGCAGCAACGTTATGATCTGGCCGAAGGGTTCCCTTTGGTGACGACCAAAAAGCTGCATCTGCGCT
CGATCATACATGAGCTGTTGTGGTTCCTGTCCGGGGATACAAACATAAGATATCTCAAAGAGAACGGTGTTTCGATCTGG
GACGAATGGGCGGATGAAAACGGCGATCTTGGTCCGGTCTATGGCTACCAGTGGCGCAAGTTTCCACGACTAGAGCTCGC
CGAGGGCACGCTTGGAGATGAGCCACTCTATCGGGCAGGCACGGTGGATCAGATCAGCGAGCTGCTGGATATGATCCGCA
AGAGCCCCGACAGCCGCCGTCTGATCGTCACCGCATGGAACCCCGGCGATGTGCCGGATATGGCGCTGCCGCCCTGTCAC
AGCCTGTGGCAACTGCGCATCCTGGGCGGCAAGATGCACCTGCAGCTCTACCAGCGCTCTGCGGATATGTTCCTCGGTGT
GCCGTTCAATATCGCTTCATATGCTTTGTTGTTGCACATGCTCGCCCATGTGACCGGCTATGAGGTGGGCAGTTTTGTGC
ATACGATGGGGGACGCGCATATCTATTCCAACCACATGGAACAGGTGAAACTGCAGCTCTCGCGCAGCCCCAAGTCCCTG
CCGCAGCTGCGCATTGCGCGCGATGTGTCTTCTATTTTTGATTTCAAATACGAGGATTTTGAAATCCTCGGCTATGATCC
CGACCCCGTCATCAAGGCCCCGGTCGCGGTCTAA

Protein sequence :
MQQYHDALQHILDHGVETTDRTGTGTLSCFGMQQRYDLAEGFPLVTTKKLHLRSIIHELLWFLSGDTNIRYLKENGVSIW
DEWADENGDLGPVYGYQWRKFPRLELAEGTLGDEPLYRAGTVDQISELLDMIRKSPDSRRLIVTAWNPGDVPDMALPPCH
SLWQLRILGGKMHLQLYQRSADMFLGVPFNIASYALLLHMLAHVTGYEVGSFVHTMGDAHIYSNHMEQVKLQLSRSPKSL
PQLRIARDVSSIFDFKYEDFEILGYDPDPVIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-71 57
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 7e-56 44