Gene Information

Name : guaA (TM1040_1375)
Accession : YP_613370.1
Strain : Ruegeria sp. TM1040
Genome accession: NC_008044
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1468257 - 1469819 bp
Length : 1563 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCGAGACAGCCCATGACCGCCTTTTAATTATAGACTTCGGCAGCCAGGTAACGCAGCTGATTGCGCGCCGCCTGCG
CGAGTTGAACGTCTATTGTGAAATCCACCCCTATCAGAATGTCACCATGGACTTCGTGCGCGAGTTCGCGCCCAAGGCGG
TGATCTTCTCTGGTGGTCCCGACAGCGTGACGCGCGAAGGCTCTCCCCGCGCGCCGCAAGAGATTTTTGACTACGGCGTG
CCGATCCTTGGCATCTGTTATGGCCAGCAAGTGATGATGCATCAGCTTGGCGGCACTGTTCAATCCGGCCATGGAACCGC
CGAATTTGGCCGCGCCTATGTGACACCCACCGAAGAGCGCATCGACATGCTCAGCGGCTGGTTCCTGGATCAGACGGAAC
AGGTCTGGATGAGCCACGGCGACCATGTCTCTGAAATCGCACCCGGTTTCAAGGTCTACGGCACCTCGCCCAACGCGCCA
TTTGCGATCACGGCGGATCTGGAGCGCAACTTCTACGCTGTTCAGTTCCACCCCGAGGTTCATCACACTCCCAACGGCAA
GACGCTCTATGAAAACTTCGTGCGTCTGGCCGGGTTCAGCGGTGACTGGACCATGGGCGCCTATCGCGAGCAGATGGTCG
AAACCATCCGCGAGCAGGTCGGCGACAAGAAAGTCATCTGTGCCCTTTCGGGTGGCGTCGACAGTTCCGTTGCGGCGGCT
CTGATCCACGAGGCGATCGGCGATCAGCTGACCTGTGTGTTTGTGGACCATGGTCTTCTGCGCAAGAACGAGGCGGAAGA
AGTCGTCGGCATGTTCCGCGACCACATGAACCTGCAGGTCATCCACGCGGATGAGACCGAGCTCTTTCTCGGTGAGCTAG
AAGGTCAGTCCGACCCCGAAACCAAGCGCAAGATTATCGGCAAGCTGTTCATCGACGTGTTCCAGAAATACGCCGATCAG
ATCGAAGGCGCGGAGTTCCTGGCCCAAGGTACGCTCTACCCGGATGTCATCGAGTCGGTCTCGTTCTCTGGTGGCCCTTC
GGTGACGATCAAGTCGCACCACAACGTCGGTGGTCTGCCCGAAAAAATGGGCCTGAAACTGGTGGAGCCGCTGCGCGAGC
TCTTCAAGGACGAAGTGCGCGCGCTCGGGCGTGAACTTGGCCTGCCCGACAGCTTTATTGGACGGCACCCCTTCCCCGGA
CCGGGTCTGGCGATCCGTTGCCCCGGCGAGATCACCCGCGACAAGCTGGACATCCTGCGCGAAGCGGATGCCATCTATAT
CGACCAGATCCGCAAACACGGTCTTTATGATGAGATCTGGCAGGCCTTTGTGGCGATCCTGCCGGTGCGCACCGTGGGCG
TGATGGGCGACGGTCGCACCTATGACTACGCCTGTGCCCTGCGCGCGGTCACCTCGGTCGATGGGATGACGGCGGATTAC
TACCCGTTCAGCCATGAGTTCCTTGGTGAGACCGCAACGCGGATCATCAATGAAGTCAAAGGCATCAACCGTTGCACCTA
TGACATCACCTCAAAGCCTCCGGGCACGATCGAGTGGGAATGA

Protein sequence :
MTETAHDRLLIIDFGSQVTQLIARRLRELNVYCEIHPYQNVTMDFVREFAPKAVIFSGGPDSVTREGSPRAPQEIFDYGV
PILGICYGQQVMMHQLGGTVQSGHGTAEFGRAYVTPTEERIDMLSGWFLDQTEQVWMSHGDHVSEIAPGFKVYGTSPNAP
FAITADLERNFYAVQFHPEVHHTPNGKTLYENFVRLAGFSGDWTMGAYREQMVETIREQVGDKKVICALSGGVDSSVAAA
LIHEAIGDQLTCVFVDHGLLRKNEAEEVVGMFRDHMNLQVIHADETELFLGELEGQSDPETKRKIIGKLFIDVFQKYADQ
IEGAEFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPEKMGLKLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPG
PGLAIRCPGEITRDKLDILREADAIYIDQIRKHGLYDEIWQAFVAILPVRTVGVMGDGRTYDYACALRAVTSVDGMTADY
YPFSHEFLGETATRIINEVKGINRCTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-126 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-126 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-126 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-113 49