Gene Information

Name : TM1040_3606 (TM1040_3606)
Accession : YP_611835.1
Strain :
Genome accession: NC_008043
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 655964 - 657247 bp
Length : 1284 bp
Strand : +
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase: (8.3e-37); KEGG: bbr:BB2925 capsular polysaccharide biosynthesis protein, ev=1e-161, 65% identity

DNA sequence :
ATGGCAGATGGCCAGCCGAACCAAGAACAGATCTGCGTAATTGGTCTCGGCTATGTCGGGTTGCCGCTCGCCGTGGAGTT
TGGACGCAGCCGCCCTGTGATCGGCTTTGACATCGACCAGAGCCGAATAGATGAGCTGCGCCTCGGCGATGATCGCACGC
GTGAAATCGACAGGGATACACTGCAGAGTGCGCAACATTTGGCGCTGACCTCCGACATCTCCGAGATTGCGGCGGCATCG
ATCTATATCGTGACCGTTCCAACCCCGATTGATGCGACTCGTCGCCCGGATCTGCGTCCTTTGTTGTCGGCGACGCGCAC
CGTTGCGCAGGTGTTGAAGCCCGGCGATACCGTCATCTATGAGTCTACGGTCTATCCCGGCGCGACCGAAGAGGACTGCG
TACCTTTGCTCGAGGAGATCTCGGGGCTGGTGTTCAATGCGGATTTTGGGGTTGGCTACAGCCCCGAGCGGATCAATCCC
GGCGACAAGACGAGACGCCTGCCCGATATTGTCAAAGTCACGTCCGGCTCCTCTCCGGAAACCGCGGCCAAAGTCGACAG
GCTCTATGCCAGCATCGTACGCGCGGGTACGTACCCGGCGCCGAGCATTCGCGTTGCCGAGGCCGCCAAGGTGATTGAGA
ACAGCCAGCGCGACATCAATATCGCCCTGATCAATGAACTTGCGAAGATCTTCAACCGGATGGAAATCGACACTGAGGCG
GTTTTGAAGGCTGCCGGCACCAAGTGGAACTTTCTGAACTTCCGTCCGGGGCTCGTCGGGGGACATTGCATAGGCGTGGA
TCCCTATTACCTGACGCACAAGGCACAAGAAGTCGGCTACCATCCGGAAATTCTGCTCTCGGGGCGCAGGCTCAATGATG
GGATGGGGGCCTATGTGGCCCAGCAGATGATCAAGGCCATGCTGCGGCGGCGCGTGCAGGTGGTCGACTCGCGTATCCTT
GTGATGGGTTTGACCTTCAAGGAAAATTGCCCCGATTTGCGCAACACCCGCGTCGTTGATGTGATTGAGGCCCTGCGCGA
CTTTGGCGTGACGGTGGATGTCTTTGACCCCCACGCAGATCCCGAAGAGGCCTACGCGGAATACGGGCTCAGGCTTATCC
AGCACCCGGAAACTGAATGTTATGACGGGACGATCCTTGCGGTGGCCCACCAGGAGTTCAAGGACATGGGCGCTGAGGTG
CTGCGCTCCTTTGGCAAGGCAGATGCCCTTCTTTATGACCTCAAATATGTGTTGCCCGCCGAGGACGCGGATCTGCGCCT
TTAA

Protein sequence :
MADGQPNQEQICVIGLGYVGLPLAVEFGRSRPVIGFDIDQSRIDELRLGDDRTREIDRDTLQSAQHLALTSDISEIAAAS
IYIVTVPTPIDATRRPDLRPLLSATRTVAQVLKPGDTVIYESTVYPGATEEDCVPLLEEISGLVFNADFGVGYSPERINP
GDKTRRLPDIVKVTSGSSPETAAKVDRLYASIVRAGTYPAPSIRVAEAAKVIENSQRDINIALINELAKIFNRMEIDTEA
VLKAAGTKWNFLNFRPGLVGGHCIGVDPYYLTHKAQEVGYHPEILLSGRRLNDGMGAYVAQQMIKAMLRRRVQVVDSRIL
VMGLTFKENCPDLRNTRVVDVIEALRDFGVTVDVFDPHADPEEAYAEYGLRLIQHPETECYDGTILAVAHQEFKDMGAEV
LRSFGKADALLYDLKYVLPAEDADLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-130 61
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-130 61
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-107 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TM1040_3606 YP_611835.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 4e-130 61