Gene Information

Name : murD (PSEEN4487)
Accession : YP_609953.1
Strain : Pseudomonas entomophila L48
Genome accession: NC_008027
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 4801198 - 4802544 bp
Length : 1347 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
GTGTCACTGATCGCTTCCGACCAATTCCGCATCGTTGTCGGCCTCGGCAAGAGCGGCATGTCCCTGGTTCGCTTCCTGGC
GAGCCGGGGCATCGCCTTTGCGGTCGCCGACACTCGCGAGCAACCGCCGGAACTGGATACCCTGCGCCGTGATTACCCGC
AGGTGGAAGTGCGCTGTGGCGAGCTGGACGTCGACTTCCTCTGCCGCGCCAACGAGCTGTACGTGAGCCCCGGCCTGGCG
CTGGCCACTCCGGCCCTGCAGCAGGCCGCGGCGCGGGGCGTGACGCTGTCCGGCGACATCGAGCTGTTCGCCCGCCACGC
CAAAGCACCGATCATCGCGATCAGTGGCTCCAACGCCAAGAGCACCGTGACCACCCTGGTCGGCGAGATGGCCGCCCAGG
CAGGCAAACGTGTGGCAGTGGGCGGCAACCTGGGCACGCCGGCGCTGGACCTGCTCGACGACAGCGTGGAGCTGTACGTG
CTCGAGCTTTCGAGCTTCCAGCTGGAGACCACCGACCAGCTCAATGCCGAAGTGGCCACCGTGCTGAACATCAGCGAGGA
CCACATGGACCGCTACAGCGGCCTGCCGGCCTATCACCTGGCCAAGCACCGGATCTTCCGCGGTGCCCGCCAGGTGGTGG
TGAACCGCCAGGATGCCCTGAGCCGTCCGCTGCCGGTCGAAGGTCGCCCGAGCTGGAGCTTTGGTCTGAATGCGCCGGAC
TTCAAGGCCTTCGGGCTGCGGGAAGTCGATGGCGAGAAGCACCTGGCCTTCGAGTTCCAGACGCTTATGCCGGTACGTGA
ATTGAAGATCCGTGGCGCTCACAACCAGAGCAATGCCCTGGCCGCGCTGGCCCTTGGCCATGCCGCCGGCCTGCCGTTCG
AGCCCATGCTCGAGGCGTTGCGCGAGTTCAAGGGCCTGGCCCATCGCTGTCAGTGGGTCCGTGAACGCAATGGCGTGAAC
TGGTACGACGATTCCAAGGCCACCAACGTCGGTGCCGCCTTGGCCGCCATCGAAGGCTTGGGTGCCGATATCGAGGGCAA
GCTGGTGCTGATCGCCGGTGGCGATGGCAAGGGCGCGGACTTCGCCGCCTTGCGCGAGCCTGTGGCCCAGCACTGCCGCG
CCGTGGTGCTGCTTGGCCGTGACGCCGAGCGCCTGGCCGAAACCTTGGGCGATACCGTGCCACAAGTGCGGGTCAAGACC
CTCGACGAAGCCGTGCAACGCTGCGCCGAACTCGCCCAGCCTGGTGATGCAGTGCTGCTGTCGCCCGCTTGCGCCAGCCT
CGACATGTTCAAGAACTTCGAAGAACGCGGGCGCCTGTTCGCCCAGGCGGCGGAGGGGTTGGCATGA

Protein sequence :
MSLIASDQFRIVVGLGKSGMSLVRFLASRGIAFAVADTREQPPELDTLRRDYPQVEVRCGELDVDFLCRANELYVSPGLA
LATPALQQAAARGVTLSGDIELFARHAKAPIIAISGSNAKSTVTTLVGEMAAQAGKRVAVGGNLGTPALDLLDDSVELYV
LELSSFQLETTDQLNAEVATVLNISEDHMDRYSGLPAYHLAKHRIFRGARQVVVNRQDALSRPLPVEGRPSWSFGLNAPD
FKAFGLREVDGEKHLAFEFQTLMPVRELKIRGAHNQSNALAALALGHAAGLPFEPMLEALREFKGLAHRCQWVRERNGVN
WYDDSKATNVGAALAAIEGLGADIEGKLVLIAGGDGKGADFAALREPVAQHCRAVVLLGRDAERLAETLGDTVPQVRVKT
LDEAVQRCAELAQPGDAVLLSPACASLDMFKNFEERGRLFAQAAEGLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 6e-83 54
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 6e-83 54