Gene Information

Name : guaA (PSEEN4392)
Accession : YP_609860.1
Strain : Pseudomonas entomophila L48
Genome accession: NC_008027
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4691527 - 4693104 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCTCGACATTCACGCTCACCGCATCCTGATCCTCGATTTCGGTTCCCAGTACACCCAGCTGATCGCCCGCCGCGT
GCGCGAAATCGGTGTGTACTGCGAGCTGCACCCGTTCGACATGGACGATGAAGCGATCCGCGAATTCAACCCGCGCGGCA
TCATCCTGGCCGGTGGCCCCGAGTCGGTCCACGAAGCCAACAGCCCACGCGCCCCGCAGGCCGTGTTCGACCTGAAGGTC
CCGGTGCTGGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTCGAAGGTTCCGACCTGCGCGA
GTTCGGCTACGCCCGCGTCGACGTGGTCGGCAAGAGCCGCCTGCTCGACGGCATCGAAGACCACGTCGACGATGACGGCG
TGCTGGGCCTGGACGTGTGGATGAGCCACGGCGACAAGGTCACCCAGATGCCAGGCAACTTCAGCGTGCTGGCCAGCACC
CCGAGCTGCCCGATCGCCGGCATGTACGACGATGCCCTGGGCTACTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CAAGCAGGGCGGTCGCATCCTGTCGCGCTTCGTCCAGGACATCTGCGGCTGTGAAGCCCTGTGGACGGCTTCGAACATCG
TCGAAGACGCCATCGCCCAGGTACGCGCACAGGTTGGTTCGGCCAACGTCCTGCTGGGCCTGTCCGGCGGCGTTGACAGC
TCGGTGGTTGCCGCGCTGCTGCACCGCGCCATCGGCGACCAGCTGACCTGCGTGTTCGTTGACAACGGCCTGCTGCGCCT
GCACGAAGGTGACCAGGTGATGGCCATGTTCAAGGAGAACATGGGCGTCAAGGTGATCCGCGCCGACGCTGAAAAGCAGT
TCCTCGACAACCTGGAAGGCGAAGCGGACCCTGAGAAGAAGCGCAAGATCATCGGCCGCACCTTCATCGACGTGTTCGAT
GCCGAAGCCAGCAAGCTGGAGAACATCCAGTTCCTCGCCCAAGGCACCATCTACCCTGACGTGATCGAGTCGGCCGGCGC
CAAGAGCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTCGGTGGCCTGCCGGAGGAGATGAACCTCAAGCTGGTCG
AGCCGTTGCGCGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCGTACGACATGGTCTACCGC
CACCCGTTCCCGGGCCCGGGCCTGGGGGTGCGCATCCTGGGTGAAGTGAAGAAAGAGTACGCCGATATCCTGCGTCGCGC
CGACCACATCTTCATCGAAGAGCTGCGCAAGGCCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCGG
TCAAGTCGGTCGGCGTCGTCGGCGACGGCCGTCGCTACGCCTGGGTCGTGGCCCTGCGTGCCGTCGAGACCGTGGACTTC
ATGACCGCGCGCTGGGCGCACCTGCCGTACGAGCTGCTGGAAACCGTCAGCGGCCGTATCATCAACGAAATCGACGGCAT
CTCCCGCGTCACCTACGACGTGTCGAGCAAGCCGCCGGCCACTATCGAGTGGGAATGA

Protein sequence :
MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLKV
PVLGICYGMQTMAEQMGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDDDGVLGLDVWMSHGDKVTQMPGNFSVLAST
PSCPIAGMYDDALGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTASNIVEDAIAQVRAQVGSANVLLGLSGGVDS
SVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLEGEADPEKKRKIIGRTFIDVFD
AEASKLENIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDF
MTARWAHLPYELLETVSGRIINEIDGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-126 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-126 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-126 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-110 48