Gene Information

Name : hpaE (PSEEN3094)
Accession : YP_608653.1
Strain : Pseudomonas entomophila L48
Genome accession: NC_008027
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.-
Position : 3306286 - 3307746 bp
Length : 1461 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737515, 8550403; Product type e : enzyme

DNA sequence :
ATGATCAAGCACTGGATCAACGGCCGCGAAGTCGAGAGCCGTGACACCTTCGTCAACTACAACCCGGCCACCGGCGAGGC
CATCGGCGAAGTGGCCAGCGGCGGCGCCGATGAAGTCGCCCAGGCCGTGGCCGCGGCCAAGGATGCCTTCCCGAAATGGG
CCAACACCCCCGCCAAGGAACGTGCGCGGCTGATGCGTCGCCTGGGCGAGCTGATCGACCAGAACGTGCCGCAACTGGCC
GAGCTGGAGACCCTGGACACCGGCCTGCCGATCCACCAGACGCGCAACGTGCTGATCCCCCGCGCCTCGCACAACTTCGA
TTTCTTCGCCGAAGTGTGCACACGCATGGACGGCCACAGCTACCCGGTCGACGACCAGATGCTCAACTACACCCTGTACC
AGCCGGTGGGCGTGTGCGGGCTGGTGTCGCCGTGGAACGTGCCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTG
GCGCTGGGCAACACGGCGGTGCTGAAGATGAGCGAGCTGTCGCCGCTCACCGCCAACGAGCTGGGCCGCCTGGCGGTCGA
GGCCGGCATCCCCAACGGTGTGCTGAACGTCATCCAGGGCTACGGCGCCACGGCCGGCGACGCGCTGGTGCGCCACCCGG
ACGTGCGGGCCATCTCCTTCACCGGCGGCACCGCCACCGGCAAGAAGATCATGCAGACCGCGGGCCTGAAGAAGTACTCC
ATGGAGCTGGGCGGCAAGTCGCCGGTGCTGATCTTCGAGGACGCCGACCTGGACCGCGCGCTGGACGCCGCGCTGTTCAC
CATCTTCTCGCTCAATGGCGAGCGCTGCACCGCCGGCAGCCGGATCTTCATCCAGCAGAGCGTGTACGCGCAGTTCGTCG
CCGAGTTCGCCGCCCGCGCCAAGCGCCTGATCGTGGGCGACCCGACCGACCCGAAGACCCAGGTCGGCTCGATGATCACC
CAGCAGCACTACGACAAGGTCACCGGCTACATCCGCATCGGCATCGAGGAAGGCGCGCGCCTGGTCGCGGGCGGCCTTGA
GCGGCCCGCCGGCCTGCCGGCGCACCTGGCCAAGGGGCAGTTCATCCAGCCCACCGTGTTCGCCGACGTCGACAACCGCA
TGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGCCTGCCTGATTCCGTTCAAGGACGAAGCCGAGGCGCTACAGTTG
GCCAACGACACCGAATACGGGCTGGCCTCGTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCCCGAGGCAT
CGAAGCCGGGATGGTGTTCATCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCATTTGGAGGGGTGAAGGGCTCGGGCA
CCGGACGCGAAGGTGGGCAGTACAGCTTCGAGGTGTTCGCCGAGATCAAGAACGTGTGCCTGTCCATGGGCAGTCATCAC
ATCCCGCGCTGGGGCATCTGA

Protein sequence :
MIKHWINGREVESRDTFVNYNPATGEAIGEVASGGADEVAQAVAAAKDAFPKWANTPAKERARLMRRLGELIDQNVPQLA
ELETLDTGLPIHQTRNVLIPRASHNFDFFAEVCTRMDGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLAVEAGIPNGVLNVIQGYGATAGDALVRHPDVRAISFTGGTATGKKIMQTAGLKKYS
MELGGKSPVLIFEDADLDRALDAALFTIFSLNGERCTAGSRIFIQQSVYAQFVAEFAARAKRLIVGDPTDPKTQVGSMIT
QQHYDKVTGYIRIGIEEGARLVAGGLERPAGLPAHLAKGQFIQPTVFADVDNRMRIAQEEIFGPVACLIPFKDEAEALQL
ANDTEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKGSGTGREGGQYSFEVFAEIKNVCLSMGSHH
IPRWGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-179 78
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-69 42
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 7e-63 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-65 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpaE YP_608653.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 4e-65 41