Gene Information

Name : kdsB (PSEEN1605)
Accession : YP_607270.1
Strain : Pseudomonas entomophila L48
Genome accession: NC_008027
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1673615 - 1674379 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGCCTGGACTTCACCGTGGTGATTCCGGCCCGGCTGCGCTCCACGCGCCTGCCGGGCAAGCCGTTGCTGCCGATCGC
CGGCAAGCCGATGGTCCAGCATGTGTGGGAGCAGGCGCGTAGAAGTGGTGCCAGCCGCGTGGTCATCGCCACGGATGACG
CCAGCATCGTGGAAGCCTGCCGGGCGTTCGGCGCTGAAGTGCTGCTGACCCGCGCCGATCATGAGTCGGGTACTGATCGC
CTGGCCGAGGTCGCCGCCCAGCTGGGGCTGGCGCCCGACGCCATCGTGGTCAACGTGCAGGGTGACGAGCCACTGATTCC
GCCGGTGATCATCGATCAGGTGGCCGCCAACCTGGCGGACCATCCGGAAGCCGGCATTGCCACCCTGGCCGAGCCGATCC
ATGAGCCGGAAACCATTTTCAACCCCAACGCGGTGAAGGTAGTCAGCGACAAGCATGGCCTGGCGCTGACCTTCAGTCGC
GCACCACTGCCCTGGGCCCGGGACGCCTTCGCCAAGGACCGCAGCCAGTTGCCTGTCGGTGTGCCGTATCGTCGCCATAT
CGGCATGTATGCCTACCGCGTGGGCTTCCTCCAGGACTTCGTGGCCTGGGGCCCGTGCTGGTTGGAGCAGACCGAGTCGC
TGGAGCAATTGCGTGCCCTGTGGCACGGCGTGCGCATCCATGTCGCCGATGCCATCGAGGCGCCGGCCGTGGGTGTCGAT
ACCCCTGAAGACCTGGAGCGCGTGCGGCGCTTGCTGGAGGCCTGA

Protein sequence : 
MSLDFTVVIPARLRSTRLPGKPLLPIAGKPMVQHVWEQARRSGASRVVIATDDASIVEACRAFGAEVLLTRADHESGTDR
LAEVAAQLGLAPDAIVVNVQGDEPLIPPVIIDQVAANLADHPEAGIATLAEPIHEPETIFNPNAVKVVSDKHGLALTFSR
APLPWARDAFAKDRSQLPVGVPYRRHIGMYAYRVGFLQDFVAWGPCWLEQTESLEQLRALWHGVRIHVADAIEAPAVGVD
TPEDLERVRRLLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-40 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-40 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-40 45