Gene Information

Name : lysS (Dgeo_0903)
Accession : YP_604374.1
Strain : Deinococcus geothermalis DSM 11300
Genome accession: NC_008025
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 963577 - 965115 bp
Length : 1539 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCGCTGATCACATCCCCGATTCCCGCCGTGCGGGTCTGCATGAGCAGACCATCAGCCGCCTGAACAACCAGGACGC
GCTGCGTGCGGCGGGTTTTGAGACTCATCCCTACAGCTACCCGCAGACGCACCACAGCCGTGACGTGCTGGCCGCGCATC
CGGACGCCGAGCCGGGCCAGGAGTGGCCGGAGGAAACCTATGCGCTGGCGGGCCGCGTGACGTTGCTGCGGCACATGGGC
AAGGCGGCCTTTGCCGACCTCACCGACGAACAGGGGCGTATCCAGCTCCACTTCTCCAAGCAGGACACTGAGCACTTCAA
CGCCACGAAAAAGATCGACCTGGGTGACATCATCGGGGTCACCGGTTTTCCCTTCGTGACGAAGACCGGCCAACTCACCC
TGCGGGTCAAGTCCTGGCAGCCCCTGGTCAAGAGCCTGCACCCCCTTCCCAGCAAGTTCCATGGCCTGCAAGACGAGGAA
CTGCGCGCCCGCCGCCGATATCTGGACCTGATGGTGACGGCAGGCGTGCGGCAGAAGTTCCAGGCCCGCAGCCGCATCAT
CCGTTATCTGCGCAATGAACTGGACCGGCGGGGCTTTATGGAGGTCGAGGGGCCGACCCTCCAGGTGACGGCAGGCGGTG
CCGAGGCCCGGCCCTTTATGACGCATCACAACGCGCTCTCGCACGATTTTAAGCTGCGCATCAGCCTGGAACTGTACCTC
AAGCGGCTGCTGGTGGGCGGCTTTGAGCGGATCTACGAGATCGGTCGGGTGTACCGCAATGAGGGCATTGACCGCACCCA
CAACCCCGAGTTCACGATGCTGGAGCTGTACTGGGCCTATGTGGACTACACCGAGATTGCCCGGCTGGTCGAGGAACTGC
TCAGTGGGTTGGCGCAGGAGCTGCACGGCTCGTACACCTTCGAGTATCAGGGCCGCACGCTGGACTTCACGCCGCCTTTC
GCGCGGGTGGACTACGTGGGCGCGCTGCGCGAACACGTCCCGGGCCTGGATTTTGATCCTCTCGACCTTGACCGCCTGCG
CCAGTTCAGTGACGCGCGCTTTCCGCAGTGGAAGGACGTTCCGTCCTACAAGCTGCTTGACAAGCTGTTTGGTGAATTCG
TGGAACCGCTGCTCACGAACCCGACCTTCGTGATGGATCACCCGGCGGTGATCAGCCCGCTCGCCAAGCGGCACCGCACC
CGTCCCGGCCTGACCGAACGCTTTGAGGTCTTCTGCTCCGGCTTCGAGCTAGCCAATGCTTTTTCTGAGCTGAATGATGC
CTTCGATCAGCGTGCTCGCTTTGAGGCGCAGTCACAGCGGCGCGAGGCCGGAGACGAGGAGGCCCATGCCCAGGACGAGG
ATTTCCTGTTGGCGCTGGAATATGGGATGCCCCCCGCCGGGGGCCTGGGCATCGGGATCGACCGGCTCGTCATGCTGCTG
ACGGACAGTGATTCCATCCGCGACGTGCTGCTCTTTCCGCTGCTGCGCCCCGAGGGTCAGAGCCAGGCCGCAGAAGAGCG
TGCGGAGGCAACCCGTTAG

Protein sequence :
MSADHIPDSRRAGLHEQTISRLNNQDALRAAGFETHPYSYPQTHHSRDVLAAHPDAEPGQEWPEETYALAGRVTLLRHMG
KAAFADLTDEQGRIQLHFSKQDTEHFNATKKIDLGDIIGVTGFPFVTKTGQLTLRVKSWQPLVKSLHPLPSKFHGLQDEE
LRARRRYLDLMVTAGVRQKFQARSRIIRYLRNELDRRGFMEVEGPTLQVTAGGAEARPFMTHHNALSHDFKLRISLELYL
KRLLVGGFERIYEIGRVYRNEGIDRTHNPEFTMLELYWAYVDYTEIARLVEELLSGLAQELHGSYTFEYQGRTLDFTPPF
ARVDYVGALREHVPGLDFDPLDLDRLRQFSDARFPQWKDVPSYKLLDKLFGEFVEPLLTNPTFVMDHPAVISPLAKRHRT
RPGLTERFEVFCSGFELANAFSELNDAFDQRARFEAQSQRREAGDEEAHAQDEDFLLALEYGMPPAGGLGIGIDRLVMLL
TDSDSIRDVLLFPLLRPEGQSQAAEERAEATR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-88 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_604374.1 lysyl-tRNA synthetase VFG1668 Protein 2e-88 48