Gene Information

Name : guaA (Dgeo_0598)
Accession : YP_604069.1
Strain : Deinococcus geothermalis DSM 11300
Genome accession: NC_008025
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 637520 - 639037 bp
Length : 1518 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAGTGTTGTGATTCTCGACTTCGGCAGCCAGTTTACGCGCCTGATCGCCCGGCGCCTGCGTGAACTCGGCGCATACAG
CGTGATCCTTCCGGGAACGGCGAGCCTGGAGCGCATCGCGCAGGAAAATCCCCAGGGGATTGTGCTGTCGGGCGGTCCCA
GCAGCGTGTATGACGCCAATGCCCCGCGTCCGGCGCCGGGCGTCCTGGACCTCGACGTGCCGATTTTGGGCGTGTGCTAC
GGGATGCAGTTTCTTGCGCATGAGGCAGGCGGCGCTGTGCAGCGGGCCGGGAAACGTGAGTACGGCAAGGCGGACCTCAC
CCGCTACGGCGGCCAGCTCTTCGCCGGGATTCAGGGGGAATTTGTCGCTTGGATGAGCCACAGCGATTCGGTAACGCAGC
TTCCCCAGGGCTACGAGGTGATTGCGGCAACTGAGGACACGCCCGTCGCGGGCATTGAGAACACGGTTACCCGCCGCTAC
GGCGTGCAGTTTCACCCCGAAGTCGTCCACACGCCCAAGGGCGGGCAACTCCTGGCGAACTTCCTGGAGATTTGCGGCGT
GGCCCGCGACTGGAACGCGGAACACATCGTGGACGAACTGATCGAGGACGTGCGGCGGCAGGTGGGCGCGGGGCGTGTGC
TGCTTGCGATCAGCGGCGGTGTGGACTCCTCTACGTTGGGGCTGTTGCTTGCCCGCGCCATCGGCGACCGCTTGACCGCG
GTCTTTATCGACCATGGCTTGTTGAGGCTGGGCGAGCGCGAACAGGTGGAGGCGGCCCTGCGGCCCCTAGGCGTGAATCT
CGTGACGGTGGATGCCAGTGAGGAGTTTCTGGGTGCGCTCGCAGGCGTCTCCGACCCCGAACAGAAGCGCAAGATCATCG
GGCGCGAGTTTATCCGGGCCTTTGAGCGCGAGGCCCGGAAGTACGGCCCCTTCGACTTTCTCGCACAGGGTACCCTTTAC
CCCGATGTGATTGAGTCGGCGGGTGGGGAGGGAGCCGCCAACATCAAGAGCCACCACAACGTCGGCGGCCTGCCGGAAGA
CCTGGCGTTTAAGCTGGTCGAACCCTTCCGCACGCTCTTCAAGGATGAGGTGCGGGAGATCGCCCGTCTGCTGGGCCTTC
CCGATGCGATCCGCATGCGTCACCCCTTCCCTGGCCCGGGCCTGGCGATCCGCTGCCTGGGCGAGGTGACTCGCGAGAAA
CTCGACATCCTCAAGCGGGTGGACGACATCTTCATCAGTGGCCTGCGCGAGTTCGGCCTCTATGACGGCTGCTCGCAGGC
CCTGGCGGTCCTGACGCCGATCCAGTCCGTTGGTGTCATGGGCGACGAGCGCACCTACTCCTACACCGCCGCCCTGCGCG
CCGTCACCACCGACGACTTTATGACCGCCGAGTGGGCGCGGCTGCCCTACGAGTTTTTGGCGACGATGAGTAACCGCATC
GTCAACCAGGTCCACGAGATCAACCGCGTGGTGTACGACATTACCGGCAAGCCGCCCGCAACGATCGAGTGGGAGTGA

Protein sequence :
MSVVILDFGSQFTRLIARRLRELGAYSVILPGTASLERIAQENPQGIVLSGGPSSVYDANAPRPAPGVLDLDVPILGVCY
GMQFLAHEAGGAVQRAGKREYGKADLTRYGGQLFAGIQGEFVAWMSHSDSVTQLPQGYEVIAATEDTPVAGIENTVTRRY
GVQFHPEVVHTPKGGQLLANFLEICGVARDWNAEHIVDELIEDVRRQVGAGRVLLAISGGVDSSTLGLLLARAIGDRLTA
VFIDHGLLRLGEREQVEAALRPLGVNLVTVDASEEFLGALAGVSDPEQKRKIIGREFIRAFEREARKYGPFDFLAQGTLY
PDVIESAGGEGAANIKSHHNVGGLPEDLAFKLVEPFRTLFKDEVREIARLLGLPDAIRMRHPFPGPGLAIRCLGEVTREK
LDILKRVDDIFISGLREFGLYDGCSQALAVLTPIQSVGVMGDERTYSYTAALRAVTTDDFMTAEWARLPYEFLATMSNRI
VNQVHEINRVVYDITGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-117 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-117 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-117 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-125 52