Gene Information

Name : Dgeo_0530 (Dgeo_0530)
Accession : YP_604001.1
Strain : Deinococcus geothermalis DSM 11300
Genome accession: NC_008025
Putative virulence/resistance : Resistance
Product : major facilitator superfamily transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 556750 - 557997 bp
Length : 1248 bp
Strand : +
Note : PFAM: major facilitator superfamily MFS_1: (5.4e-52); KEGG: dra:DR0472 tetracycline-efflux transporter ev=1e-158, 74% identity

DNA sequence :
ATGCGCCAGCGACCTGCGGCCCTGATCTTCATTCTGGCAACTGCCCTGATCGATGTGATGGGCATTGGCCTGATCATTCC
CGTGCTGCCGGGGCTGGTGAAGGCGCTCGCTGGGTCGGAGGCGGCGGGCGCACGCTTTATCGGCTGGCTGACGGCAGCGT
ATGCCATCATGCAGTTCCTGTGTGCGCCGATTCTGGGGACACTCTCGGATCGCTATGGGCGGCGGCCGGTGCTGCTGCTC
AGCCTGCTGGGAATGGCCCTCGACTACGTGCTGCTTTACTTCGCCCCCAGCCTGGGGTGGTTGCTGCTGGGCCGGATCAT
TGCAGGCCTGACGGGCGCGAGCCTGACAGTGGCAAACGCCTATATCGCGGATGTGTCGCCTCCTGAGGACCGGGCGAAGA
ACTTCGGCCTGCTGGGGGCGACCTTCGGGGTGGGCTTCATCCTGGGGCCGGCGCTGGGCGGCTTTCTGGGTGACCTCGGG
CTGCGCCTCCCGTTCCTGGTGGCGGCGGGCCTCACGGGGCTGAACTTCCTGTACGGCCTCTTCGTGCTGCCCGAATCGCT
GCCCGCCTCGGCGCGGGGGCAGGCGCCGAAGCGCGGTGCCCTCAACCCCTTCACGCCGCTCAGGGCCCTGGGCGAGTACG
CCATCACGCGCAACCTCGCGGGGACGTTCGTGCTGCTGGGATTGGCGGGGCAGGTGATCTTCAGCACCTGGGTGCTGTAC
ACCGAGGCGGTGTTGAACTGGTCGCCCGCGCAGAATGGGGTGGCCCTCGCGGTCTTCGGCCTGCTGACGGCAGGCGTGCA
GGCCGGACTGATTGGCCGGGCGATCGCGGTGCTGGGTGAGCGGCGCACCATCCTGCTGGGGCTGGTCATGTCCATCGGGG
AATTCCTGCTGCTGAGCGTGGCGCGCACCCCACTGCTGCTGTACCTCTCGCTGATCTTCGGGGCGCTGGGCGGCCTCGCC
AATCCCGCCATCCAGGGCCTGATCAGCCGTCAGGTGAGGGAAACCGAGCAGGGCCGCGTGATGGGCGCGATCACCAGTCT
GAACAGCCTGGTGGGCGTGGTAGGCCCGATTCTCGCCACCGCCGTCTTCGCCTACTTCAATGGAGGCGGAGCCCCCTTCC
GCCTCCCCGGCGCGGCGTTCCTGATGGGTGCGGGCTTCGCCATGCTCGGCACGCTGCTGGTGTGGGCCGTGTTGCGGCGG
ATGCCGGTGCAACGGGCGGGCGTGGCGGGTGAGGTGAGTGGGGATTAG

Protein sequence :
MRQRPAALIFILATALIDVMGIGLIIPVLPGLVKALAGSEAAGARFIGWLTAAYAIMQFLCAPILGTLSDRYGRRPVLLL
SLLGMALDYVLLYFAPSLGWLLLGRIIAGLTGASLTVANAYIADVSPPEDRAKNFGLLGATFGVGFILGPALGGFLGDLG
LRLPFLVAAGLTGLNFLYGLFVLPESLPASARGQAPKRGALNPFTPLRALGEYAITRNLAGTFVLLGLAGQVIFSTWVLY
TEAVLNWSPAQNGVALAVFGLLTAGVQAGLIGRAIAVLGERRTILLGLVMSIGEFLLLSVARTPLLLYLSLIFGALGGLA
NPAIQGLISRQVRETEQGRVMGAITSLNSLVGVVGPILATAVFAYFNGGGAPFRLPGAAFLMGAGFAMLGTLLVWAVLRR
MPVQRAGVAGEVSGD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 2e-56 45
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 2e-56 45
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 3e-56 45
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 2e-56 45
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 2e-56 45
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 2e-56 45
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 4e-40 41
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 4e-40 41
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 4e-40 41
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 4e-40 41
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 1e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AY264780.2.gene3.p01 Protein 3e-58 47
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_010410.6002597.p0 Protein 1e-56 45
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter CP001485.1.gene2821. Protein 1e-56 45
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AF534183.gene.p01 Protein 1e-56 45
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter Y19114.gene.p01 Protein 8e-50 44
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_011586.7045189.p0 Protein 8e-54 44
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter X75761.gene.p01 Protein 7e-56 44
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter Y19116.gene.p01 Protein 1e-40 43
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter L06940.gene.p01 Protein 7e-41 43
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AY743590.gene.p01 Protein 2e-48 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AF090987.gene.p01 Protein 2e-43 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_009085.4918440.p0 Protein 8e-38 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_011595.7059241.p0 Protein 3e-37 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_011586.7043399.p0 Protein 3e-37 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_010410.6003291.p0 Protein 3e-37 42
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AF121000.gene.p01 Protein 5e-49 41
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter AF133140.gene.p01 Protein 6e-41 41
Dgeo_0530 YP_604001.1 major facilitator superfamily transporter NC_010410.6002612.p0 Protein 6e-41 41