Gene Information

Name : Dgeo_0005 (Dgeo_0005)
Accession : YP_603478.1
Strain : Deinococcus geothermalis DSM 11300
Genome accession: NC_008025
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 4600 - 6048 bp
Length : 1449 bp
Strand : +
Note : PFAM: pyruvate kinase: (9.6e-166); KEGG: dra:DR2635 pyruvate kinase, ev=0.0, 86% identity

DNA sequence :
ATGAAACACTTTGACAGGGCAACCAAGATTGTCGCCACGATCGGCCCGGCGAGCCGAAATCCAGAGACGCTCGGGCGCAT
GATCGATGCGGGCCTGAATGTGGTCCGCATGAATTTCAGTCACGGGGACCCGGAGGACCACCGTCAGACGGTGCAGCTGG
TGCGCGAGTTGGCGGCCAAGAAGGGCGTGACCATCGGTATTCTGCAAGATCTCCAGGGTCCGAAGATCCGGGTAGGCCGC
TTCCGCGAGGGCGCCGTCAAGCTGGAGCCGGGGCAGAAGTTTACCATCACGATGGACGATGTGGAGGGTGACGAGACGCA
CGTCAGCAGCACCTACAAGGGTCTGGCACTGGATGTGCATCCCGGCATGATCCTGCTGCTCGACGACGGGAACTTGGCGC
TCAAAGTTGATCAGGTGCGCGGTCAAGAGATTCTGACGACCGTCGTGATCGGCGGAGTCCTGAAGAACAACAAGGGCATC
AATGTGCCGCAGGCCGACCTTGCTGTGCCTGCGCTCTCCGACAAGGACGTACAGGACATGGAGTTCGGCGCGCAGCTGGG
GGTGGACTGGGTGGCGCTCTCGTTTGTGCGTTCGCGTGACGACCTGCTGCTGGCCCGCCATTACCTCGCCCGCTTCGGCA
GCCGGGCCAAGCTGATGGCGAAGATCGAGAAACCGCAGGCAGTGGACCGCTTCGAGGACATCTTGCGAGAGGTGGACGGC
ATCATGGTAGCGCGCGGCGACCTGGGGGTGGAGATGCGCCCTGAGCAGGTGCCGACGATCCAGAAGCGCCTGATTCGTCT
GTGCCGCGAGGCCGGGAAGCCGGTGATCACCGCCACCCAGATGCTCGAGAGCATGATCAATCTGCCGCGCCCCACCCGTG
CCGAGGCGTCCGACGTGGCGAATGCGATCTATGACGGTACCGACGCGGTGATGCTCTCGGCCGAGTCGGCGGCGGGCCAA
TACCCGGTCGAGGCGGTGGCGATGATGGACCGCATCGCGCGCGAAGCCGAAGCCAGCGAGCACTACGAGCTGATGCAGCG
TCAGCTCGTTGTAGAAACCGAGCTGGCGCAGGATTCCATTGCCTTTGCTGCTTGCTCTATCGGCGAGAAGCTGGAAGCGT
CCGCCATTGTGACCTTTACCAGCACTGGCGGAGCAGCAATGCGTGTGGCAAAGTACCGTCCCCCCCTCGCCATCCTGGCC
CTAACCCCCAATGAGCAGACCCGCAACCAGCTCGCCCTCTCGTGGGGTGTCGTGCCGATGCTCAGCGAGGATCCACACGA
TACCGACGACATGGTGCGCATCGCCAATGACGAACTGAAGAAAAGCGGCCTCGCCGATGTAGGCGACCGGTACGTCATCA
CCGCCGGCGTGCCCTTTGGCGTGCGCGGCACCACCAACATGCTGCGTGTCGAGCGACTGCGTGAGGAAGATCTGAGCGAA
AGGGTTTAA

Protein sequence :
MKHFDRATKIVATIGPASRNPETLGRMIDAGLNVVRMNFSHGDPEDHRQTVQLVRELAAKKGVTIGILQDLQGPKIRVGR
FREGAVKLEPGQKFTITMDDVEGDETHVSSTYKGLALDVHPGMILLLDDGNLALKVDQVRGQEILTTVVIGGVLKNNKGI
NVPQADLAVPALSDKDVQDMEFGAQLGVDWVALSFVRSRDDLLLARHYLARFGSRAKLMAKIEKPQAVDRFEDILREVDG
IMVARGDLGVEMRPEQVPTIQKRLIRLCREAGKPVITATQMLESMINLPRPTRAEASDVANAIYDGTDAVMLSAESAAGQ
YPVEAVAMMDRIAREAEASEHYELMQRQLVVETELAQDSIAFAACSIGEKLEASAIVTFTSTGGAAMRVAKYRPPLAILA
LTPNEQTRNQLALSWGVVPMLSEDPHDTDDMVRIANDELKKSGLADVGDRYVITAGVPFGVRGTTNMLRVERLREEDLSE
RV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-81 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-81 46
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-81 46
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-71 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dgeo_0005 YP_603478.1 pyruvate kinase VFG0479 Protein 1e-81 46