Gene Information

Name : apbA (MGAS10750_Spy0750)
Accession : YP_602244.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : -
Position : 727465 - 728388 bp
Length : 924 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGTTAGTTTATATTGCTGGCTCAGGAGCCATGGGGTGCCGTTTTGGTTACCAAATTTCAAAAACAAATAACGATGTGAT
TTTGTTAGATAACTGGGAAGATCATATCAATGCCATTAAAGAAAACGGGTTGATTGTAACAGGTGATGTGGAAGAAACAG
TTAAGCTTCCTATTATGAAATCGACTGAAGCCACTCAAGAAGCCGATTTGATTATCTTGTTTACAAAAGCAATGCAGTTG
CCACAAATGCTTCAAGACATTAAAGGCATTATTGGAAAAGAAACCAAAGTGCTTTGCCTTTTAAATGGTCTTGGACACGA
AGACGTTATTCGTCAGTACATTCCAGAGCACAACATTTTGATGGGGGTCACTGTCTGGACTGCTGGTCTAGAAGGACCAG
GTCGTGCTCATCTTCAAGGAGTTGGTGCTCTTAACTTACAAAGTATGGATCCAAACAATCAAGATGCGGGACATCAAGTG
GCTGACTTGCTAAATAAAGCTAACTTAAATGCGACTTATGATGAGAATGTTGTGCCAAACATCTGGCGAAAAGCTTGCGT
GAATGGTACCATGAATTCGACTTGTGCTCTTTTAGATTGTACGATTGGCGAATTATTTGCCAGTGAAGATGGTCTCAAAA
TGGTAAAAGAAATCATCCATGAGTTTGTTATCGTTGGTCAAGCAGAAGGTGTCGAACTAAACGAAGAAGAAATCACACAA
TATGTAATGGATACATCTGTTAAAGCTGCTCACCATTACCCATCAATGCACCAAGACCTTGTGCAAAATCACCGATTGAC
TGAAATTGATTTTATCAATGGTGCAGTCAATACCAAAGGTGAAAAGCTTGGTATCAATACTCCATACTGCCGTATGATTA
CAGAGCTAGTTCACGCTAAAGAAGCAGTGTTGAACATCCAATAA

Protein sequence :
MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLIVTGDVEETVKLPIMKSTEATQEADLIILFTKAMQL
PQMLQDIKGIIGKETKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQ
YVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAKEAVLNIQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 4e-72 50
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 3e-72 50