Gene Information

Name : fhuA (MGAS10750_Spy0318)
Accession : YP_601812.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Virulence
Product : ferrichrome transport ATP-binding protein fhuC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 328076 - 328858 bp
Length : 783 bp
Strand : -
Note : -

DNA sequence : 
ATGACAACAATTAGTGCTGAAGACCTCACAATTGCCTATGGACAGCGTACCATCATCGATAAATTATCGTTTTATATTCC
TGAAGGTAAAATTACGACCATTATTGGCGCCAATGGCTGTGGGAAGTCTAGTTTATTAAAAGCACTGACAAGATTATTAC
CACCAAAACAGGGAATTGTGTATTTAAATGGGCAAAACATTGCCACATTAGAAACTAAAGAGGTTGCTAAAAAACTAGCT
CTTTTACCTCAAGTTCAAGAAGCAACTAACGGCATAACTGTTTACGAATTGGTTTCTTACGGACGTTTTCCCCATCAATC
TTACTTTGGAAATCTTAGTCCAGCTGACAAAAAAGCCATTCATTGGGCTATGCAAGCCACCAATGTCATGGCCTATGCTG
ATCAACCTGTTGATGCTCTTTCTGGGGGGCAACGTCAAAGGGTTTGGCTTGCAATGGCATTAGCCCAAGGCACTGATACT
ATTTTTTTAGATGAGCCAACTACTTATTTAGATTTAAATCATCAACTAGAAATCCTAGAGCTCGTTAAATCCCTAAATAA
GGATGCCGGCAAGACTATTGTTATGGTTCTTCACGACCTCAATCTTTCAGCCCGCTATTCGGATCATCTGATTGCTATGA
AACATGGCAAGATCCATTATACTGGTACTATAGCAGATGTTATGACTTCACCTATCATTCAAGACATCTTCCTAATCAAA
CCGGTACTGGTTGATGATCCTATCCACAACTGTCCTATAGTGCTGACTTATCAGCTTCAATAA

Protein sequence : 
MTTISAEDLTIAYGQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGIVYLNGQNIATLETKEVAKKLA
LLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFLIK
PVLVDDPIHNCPIVLTYQLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 6e-59 47
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-57 47
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 2e-57 47
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-57 47
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-57 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 1e-52 45
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 1e-52 45
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 1e-52 45
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-50 45
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-51 44
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-51 44
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-51 44
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-51 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuA YP_601812.1 ferrichrome transport ATP-binding protein fhuC BAC0164 Protein 7e-53 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuA YP_601812.1 ferrichrome transport ATP-binding protein fhuC VFG0925 Protein 2e-58 47
fhuA YP_601812.1 ferrichrome transport ATP-binding protein fhuC VFG1042 Protein 7e-53 45