Gene Information

Name : metB (MGAS10750_Spy0152)
Accession : YP_601646.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 164118 - 165509 bp
Length : 1392 bp
Strand : +
Note : -

DNA sequence :
GTGTTGGCAGCTTGGTCAAAGATGATAAAAGGGCTTGCAAACTTAGCTAAAGGTTGTATAATAAATGTAATCGATCTAAA
AATGATATTGTTGGAAAAATTCATTATTCATTTAAAAGGTGCCCACTACTTTTCTTATAGGTTAGCAGATCACGCTTTTT
TGAAGAGCTTTTTGGTTTGTGCAACCATTGGGGTGGGACCATTGTCTAAAAGAGAGTTCATTGGAGTTAACGCTATTGCG
GAGGTGCACGAAATGAGAGAAAATACGACCTTATTACATGGCTATACGGTTATTGACGAGTTTACAGGAGCAGCTTCAGT
TCCCATCTATCAGACTTCGACGTTCCACAATTCAGAACTGTATTGTCCTAGTCAAAAACATTTGTACACACGCTTTTCAA
ACCCAACGACTGAAGCTTTAGAAGACGGGTTAGCCTGTTTAGAAAAAGCGACTTATGCGGTGGCTTATGCATCTGGTATG
GCTGCTATTTCAACTGTTTTGATGCTCTTAAAAGCCGGAGATCATGTGATTTTCCCATTGGAGGTCTATGGAGGGACTTG
TCAATTTGCGACAGCTATTTTACCCAATTATCAGATTGAAACAAGCTTTGTAGATATGGCTGATTTAGCAACAGTAAAAG
CAAGTATCAGACCTAATACGCGTATGATTTATCTAGAGACACCGTCAAATCCGCTCTTGAAAATTTGTGATATTTCAGAG
CTTGTGCAACTCGCCAAAGCTTATGGTGTGCTAACTGTGGCTGATAATACCTTTATGACAAGTTTGTATCAAGAACCCTT
AGCTATGGGTGTGGATATTGTGGTAGAAAGTGTGACCAAATTTATCAATGGTCATAGTGATGTGGTAGCTGGTTTAGCTG
CTACCAATAATGAGGCTATCTACAACCAGCTCAAGCTTTTTCAAAAAAACTTTGGAGCAATTGTTGGGGTCGAAGACGCT
TGGCTGATTCTTCGTGGCATGAAAACTATGGGGATCCGTATGGAACAAGCGGTAAAAAATGCTCAGCAGCTCGCTAATTA
TTTAGCGAAGCACCCCAAAGTTCTTAAGGTACATTACCCTGGCTTAGACAGTCATCCTAATCACGATACCCACCTGCAAC
AAGCTAAGAATGGTGGTGCTGTTTTATCCTTTGAGTTGGCTTCTAAGGAGGAGCTGATGACCTTTACCCATCGTATTCAG
TTGCCGATTTTAGCCGTTAGTCTAGGTGGAGTAGAGTCCATTTTGTCACATCCAGCAACGATGTCTCATGCTTGTTTATC
GTCACAAGCGCGGTTGGAACAAGGGGTTGTTGATGGTTTGCTGCGCTTGTCTTGTGGTGTTGAAAATATCGAAGATTTAT
TGGCCGATTTTGAGCAAGCACTTGCTTTTTAA

Protein sequence :
MLAAWSKMIKGLANLAKGCIINVIDLKMILLEKFIIHLKGAHYFSYRLADHAFLKSFLVCATIGVGPLSKREFIGVNAIA
EVHEMRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHLYTRFSNPTTEALEDGLACLEKATYAVAYASGM
AAISTVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISE
LVQLAKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYNQLKLFQKNFGAIVGVEDA
WLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYPGLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQ
LPILAVSLGGVESILSHPATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 0.0 99
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-77 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-77 43