Gene Information

Name : slo (MGAS10750_Spy0147)
Accession : YP_601641.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Virulence
Product : streptolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 160041 - 161765 bp
Length : 1725 bp
Strand : +
Note : -

DNA sequence :
ATGAAGGACATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTGACGGCAGCTCTTATCATTGG
TAATCTTGTTACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAA
AGCCAGAAAGTAGTGAGCTAACTACTGAAAAAGCAGGTCAGAAAACGGATGATATGCTTAACTCTAACGATATGATTAAG
CTTGCTCCCAAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGA
TCACACTGAAGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCA
TTGAAAATTTTGCTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAAC
ACTACACCAGTCGATATTTCCATCATTGACTCTGTCACTGATAGGACCTATCCAGCAGCCCTTCAGCTGGCTAATAAAGG
TTTTACCGAAAACAAACCAGACGCGGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAG
ACAAAGCAACGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTATTAACCAATGGCAT
GATAATTATTCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAGTCACAGATTGA
AGCAGCTCTAAATGTTAATAGTAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGA
AGGTGATGATTGCAGCATACAAGCAAATTTTTTACACTGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGCT
AAATCAGTGACCTTTAAAGAGTTGCAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAATGTAGCCTA
TGGTCGAACTGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAG
GAACAGATGTTAAAACTAATGGAAAATATTCTGATATCTTAGAAAATAGCTCATTTACAGCTGTCGTTTTAGGAGGAGAT
GCTGCAGAGCACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGACAATGCTACCTTCAGTAG
AAAAAACCCAGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAACTG
AATACGTTGAAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCATCAAGGCGCGTATGTTGCTCAATAT
GAAATCCTTTGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGACAACAACTGGTA
TAGTAAGACATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATACGTATCATGGCTAGAGAGTGCA
CCGGCTTAGCTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATCAATGTCAACATC
TCAGGATCAACCCTGAGCCCATATGGTTCGATTACTTATAAATAG

Protein sequence :
MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTTEKAGQKTDDMLNSNDMIK
LAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFAPKEGVKKADKFIVIERKKKNIN
TTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLINQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFA
KSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGD
AAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHQGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNI
SGSTLSPYGSITYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 0.0 99
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-93 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
slo YP_601641.1 streptolysin O VFG0976 Protein 0.0 99
slo YP_601641.1 streptolysin O VFG2275 Protein 3e-149 66
slo YP_601641.1 streptolysin O VFG1363 Protein 3e-91 43
slo YP_601641.1 streptolysin O VFG0074 Protein 2e-93 42