Gene Information

Name : ulaA (MGAS10750_Spy1756)
Accession : YP_603250.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Virulence
Product : PTS system ascorbate-specific transporter subunit IIC
Function : -
COG functional category : S : Function unknown
COG ID : COG3037
EC number : -
Position : 1703926 - 1705305 bp
Length : 1380 bp
Strand : -
Note : membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr

DNA sequence :
ATGGAAGCATTATTATCATTTATTCGAGATATTTTAAAAGAACCTGCATTTTTAATGGGCTTGATTGCCTTTGCAGGGTT
GGTGGCTTTGAAAACACCTGCTCATAAGGTGTTGACAGGAACCTTGGGGCCGATTTTGGGATACCTTATGCTTGCTGCAG
GGGCGGGTGTTATTGTGGCCAATCTGGACCCTCTTGCCAAACTCATTGAGCACGGTTTTAGCATCACTGGCGTAGTGCCA
AATAATGAAGCCGTCACTTCTGTCGCTCAAAAGATTCTGGGTGTGGAAACCATGTCCATCTTGGTGGTTGGGTTATTGCT
CAATTTGGCTTTTGCTCGTTTTACCCGCTTCAAATACATTTTCTTAACAGGACATCACAGCTTCTTTATGGCTTGTCTCT
TGTCCGCCGTGCTTGGAGCTGTTGGTTTCAAAGGAAGTCTTTTGATTATCTTAGGTGGGTTCCTCTTGGGAGCTTGGTCA
GCTATTTCGCCAGCCATTGGTCGACAGTATACGTTGAAAGTGACTGACGGAGATGAAATCGCCATGGGACACTTTGGTAG
TTTGGGCTATTACCTTTCTGCCTGGTTTGGTAGCAAGGTTGGCAAAGACAGTAAAGATACCGAGGACCTTCAGATTTCTG
AAAAATGGAGTTTCTTACGCAACACCACCATTTCAACAGGGCTTATCATGGTGATTTTCTACTTGGTGGCAACAGTGGCT
TCTGTTTTGAGGAATGCTTCAGTAACAGAAGAATTAGCAGCAGGTCAAAACCCATTTATCTTTGCTATTAAGAGTGGTCT
TACCTTTGCGGTTGGTGTGGCAATTGTCTACGCCGGTGTTCGCATGATTTTGGCTGACTTGATTCCAGCCTTCCAAGGTA
TTGCTAACAAATTAATTCCAAATGCTATTCCAGCTGTAGACTGTGCGGTATTCTTCCCTTATGCGCCAACCGCTGTTATC
ATCGGTTTTGCGTCAAGTTTCGTTGGTGGCTTACTTGGGATGTTGATTTTAGGAGTTGCAGGTGGTGTCCTGATTATCCC
AGGTATGGTGCCTCATTTCTTCTGCGGTGCAACAGCAGGGATTTTTGGAAATTCAACAGGTGGTCGTCGCGGTGCAATGA
TTGGTGCTTTCGCTAATGGCTTATTACTCGCCTTCTTGCCAGCCATGCTTCTACCTGTACTTGGTAAACTTGGTTTTTCA
AACACGACCTTTGGAGATGTGGATTTCGGTGTTTTAGGGATTTTACTGGGCCGCTTAGGAACGTCGATTGGTCAAATCGG
TATTTACTTGGTGGTTGCTGTGCTTGCTATTGTATTGGTGCTTCCAAACTTTCTGTCAAAATCTCAAGAAGCCATCAATA
ATGTTTCAGAAGAAATCTAA

Protein sequence :
MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGPILGYLMLAAGAGVIVANLDPLAKLIEHGFSITGVVP
NNEAVTSVAQKILGVETMSILVVGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
AISPAIGRQYTLKVTDGDEIAMGHFGSLGYYLSAWFGSKVGKDSKDTEDLQISEKWSFLRNTTISTGLIMVIFYLVATVA
SVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIVYAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVI
IGFASSFVGGLLGMLILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLPVLGKLGFS
NTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQEAINNVSEEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF8 AAK27335.1 unknown Not tested PAI-I AL862 Protein 2e-74 50
unnamed CAC39291.1 hypothetical protein Not tested LPA Protein 1e-74 50
vpeC ADD91725.1 putative PTS system-specific IIC component VpeC Virulence PAI-I AL862 Protein 1e-74 50