Gene Information

Name : MGAS10750_Spy1696 (MGAS10750_Spy1696)
Accession : YP_603190.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1637352 - 1639085 bp
Length : 1734 bp
Strand : +
Note : -

DNA sequence :
ATGGAGGTATTAATGAAGTTAGTAATAGCAGAAAAGCCAAGTGTAGCAGTTACAATTGCAAAAATAATTGGAGCAAGAAC
AAGAAAAAACGGATATTATGAGGGGAATGGATACATTGTTTCTTGGTGTGTAGGTCATTTAATTCAAATGGCAAGTCCCG
ATAAGATAGACGAAAAATGGAAGAAATGGACAATAGAAAACCTTCCTATAATTCCAGAAGAATATATTTATGAAGTATCT
AAAAGTACTAAAAAACAATATGGAGTTTTAAAGAAACTTTTAAACGATAAGAACATCAACATAGTTATAAATGCTTGTGA
TGCTGGAAGAGAGGGAGAACTTATTTTTAGGCTTGTATATAATCAAGCTAAATGTAAGAAGAAGATTCAAAGACTTTGGA
TATCTTCAATGGAAAACGAAGCTATTGAAGATGGATTTAGAAATCTTAAAGACGGAGAAAAATTTGAAGACTTATATAGA
TCAGCAAGTGCAAGAGCAATTGCGGATTGGCTGGTGGGAATGAATTTAAGTAGGCTTTATTCTTGCATTTACAAGGAAAC
ATATTCAGTTGGTAGAGTACAAACACCAACTCTATATTTAATAGCTAAAAGGGATAGCGAAATAAACCTATTTAAGAAGC
AAAAATATTATACAGTTGACCTATCTTATGGAGGATTGAAACTTGTATCAGATAGGATTGATAGAATTGAAGTTGCAGAA
CAACTATTAAATCTACTAGAAGATGAAATAGTTATTACAGAGGTAGAAGATAAAGAGGTAAGCACAAAACCAGATAAGCC
TTATGATCTCACTACCTTACAAAGAGAAGCAAATAAATATTTTGGATATTCAGCAAATGACACTTTAAATCTAGCACAAG
CTTTGTATGAAAAAAAGCTAATCACATATCCAAGAACAGATAGCAGGTATTTAACCGATGACATGGTTAATACTATGAAA
GAATTATTAGAAGGACTTGAAGAAGATTTTAAACTCAACAAATCAAACTTTAAGTCTATTTTTAATTCATCTAAGGTTAC
AGACCACTATGCAATTATTCCTACTATATCAGGTATTGGAAAAGCCAAAGATTTATCTGATAAAGAAAGCAAAGTCTATA
ATCTAATTAAGGATAAACTACTTGCTTCATGTTCGGATAACTTAAAGGAATCTAGTAGAAAAATCAGATATGAATATGAT
AAATTTAACTTCAATGCAAGTGGAAAGACTATAATCGATGAAGGTTATACCAAGTATCTAAAGGCTTATGGAAAAGAAAA
GCAAGAAAATGAATTACCAGATGTAAAGACTGGAGATAAAATTAAGCTAACTTCTAAAAATATATCGGAGAAATTTACAA
AAGCTCCAAGTCATTATAATGAAGATACACTTTTAAAGGCTATGGAAAATGCAGGAGTAGAATCCTTGGATAAAGACATA
GAAGTGGAGAGAAAAGGCTTAGGAACGCCAGCTACGAGAGCAGGAATTATTGAAAATCTTATCCATAAGGAACTCATAAG
AAGAGATAAGAAAAATTTACTTGTAACAGAAAAAGGCAATAGGCTTGTATCTATTGTAGAGGATAAGTTTAAATCAGCAG
AAACAACATCTGAATGGGAAATGAAACTTGCGAAGATTAACTCTGGCGAAGTAGATAAAGAAGACTTTTTAAGAGAAATA
GAAGATAGTATAAGGGAGCTTGTAGATAGGTACAAGAATAATCTAAATGAATAA

Protein sequence :
MEVLMKLVIAEKPSVAVTIAKIIGARTRKNGYYEGNGYIVSWCVGHLIQMASPDKIDEKWKKWTIENLPIIPEEYIYEVS
KSTKKQYGVLKKLLNDKNINIVINACDAGREGELIFRLVYNQAKCKKKIQRLWISSMENEAIEDGFRNLKDGEKFEDLYR
SASARAIADWLVGMNLSRLYSCIYKETYSVGRVQTPTLYLIAKRDSEINLFKKQKYYTVDLSYGGLKLVSDRIDRIEVAE
QLLNLLEDEIVITEVEDKEVSTKPDKPYDLTTLQREANKYFGYSANDTLNLAQALYEKKLITYPRTDSRYLTDDMVNTMK
ELLEGLEEDFKLNKSNFKSIFNSSKVTDHYAIIPTISGIGKAKDLSDKESKVYNLIKDKLLASCSDNLKESSRKIRYEYD
KFNFNASGKTIIDEGYTKYLKAYGKEKQENELPDVKTGDKIKLTSKNISEKFTKAPSHYNEDTLLKAMENAGVESLDKDI
EVERKGLGTPATRAGIIENLIHKELIRRDKKNLLVTEKGNRLVSIVEDKFKSAETTSEWEMKLAKINSGEVDKEDFLREI
EDSIRELVDRYKNNLNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EFAU085_00720 YP_008394244.1 DNA topoisomerase III Not tested Not named Protein 2e-109 45
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 4e-114 42