Gene Information

Name : MGAS10750_Spy1573 (MGAS10750_Spy1573)
Accession : YP_603067.2
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : -
Position : 1502121 - 1503335 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCT
ATCATGCAATATTGTCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATGTCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCGGTCCATTATCTTTGTAATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGCACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCTCTTTATCCTAA
GGAGATTTTAGAAGACATTGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATGGTAAAGAGCATATTGCTATTGCAAGTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTGAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCCCAACAAGTTGTTCAAACTTCCTTAGGAGGCCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAAGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTCCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Protein sequence :
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCNEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-117 57
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-117 57
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 3e-117 57
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-117 57